TableĀ 2 Cardiac diseases which have been modelled in vitro using iPSC-CMs. Many drugs have been tested using disease state iPSC-CMs
DiseaseTested drug(s)
LQT1Propranolol [77], isoprenaline [78]
LQT2Nifedipine [38], propranolol [79], allele-specific siRNA [80], cisapride [81]
LQT8Roscovitine [39]
CPTV1Isoprenaline, forskolin [35]
DCMMetoprolol, norepinephrine [82]
HCMPropranolol, verapamil, nifedipine [36]
ARVCNifedipine [83], isoproterenol [84]