Table 2 Comparisons of subunit rotation angles and tetramer fits among different M2PYK crystal structures

4FXJ: A published crystal structure with M2PYK-R489A and ligand phenylalanine.

4B2D: A published crystal structure with M2PYK/FBP/Ser.

4FXF: A published crystal structure with M2PYK/FBP.

3SRF: A published crystal structure with M1PYK.

AlaPheTrpSer4FXJ4B2D4FXF3SRF
Ala 3.233.669.13.569.259.199.29
Phe1.450.4711.280.3811.2311.1211.76
Trp1.580.26 11.520.5911.5311.3712.05
Ser3.654.684.7611.500.651.081.66
4FXJ1.490.380.604.68 11.4011.2511.99
4B2D3.704.694.790.424.680.971.99
4FXF3.334.234.330.934.240.93 2.71
3SRF3.885.005.100.955.011.061.55

Italics: RMS fit (Å) (tetramer–tetramer best fit, calculated with Cα atoms). Bold: subunit rotation angles (°) (calculated based on the tetramer–tetramer RMS best fit).