Table 1 Selective inhibition of COX enzymes

IC50 values were determined as the concentration of the compound required to inhibit 50% of the PGE2 production.

IC50 (μM)
AdditiveCOX1COX2
DHA13.5>50
B18.0>500
B2>5009.7
C1>5003.3
Indomethacin0.630.99
Nimesulide19.04.9
sc-5600.134.4