Table 2 Summary of bacterial FAS regulation
EffectorTargetLigandConsequence
Acyl-ACPACC-FAS inhibition
Acyl-ACPFabH-FAS inhibition
Acyl-ACPFabI-FAS inhibition
PpGppPlsB-PlsB inhibition
SpoTppGpp synthesisAcyl-ACPFAS inhibition
Transcription level regulation
FabTFAS genesAcyl-ACPFAS inhibition
FapRFAS genesMalonyl-CoA or- ACPFAS activation
FadRfabA, fabBAcyl-CoAActivation
FabRfabA, fabBSaturated acyl-CoA or -ACPActivation
FabRfabA, fabBUnsaturated acyl-CoA or -ACPRepression