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Editorial Board
Chair
PR Shepherd - Auckland

Vice Chair, The Americas
G Salvesen - La Jolla, CA

Vice Chair, Asia-Pacific
T Xu - Beijing

Vice Chair, Europe
DR Alessi - Dundee

Vice Chair, Reviews
A Toker - Boston, MA

Deputy Chairs
M Blatt - Glasgow
L Goodyear - Boston, MA
SV Graham - Glasgow
D Hoekstra - Groningen
S Huber - Urbana, IL
J Ladbury - Houston, TX
M Lemmon - Philadelphia, PA
C MacKintosh - Dundee
KH Mayo - Minneapolis, MN
M Murphy - Cambridge
S Roberts - Buffalo, NY
M Schwartz - Charlottesville, VA
D Tosh - Bath
B Vanhaesebroeck - London
HM Wallace - Aberdeen

Latest Reviews

Forthcoming Reviews | Current Reviews | Reviews archive |

Volume 427

Wnt signalling and the control of cellular metabolism
J. K. Sethi and A. Vidal‑Puig..........1‑17
Published on the Internet 15 March 2010, doi:10.1042/BJ20091866
Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Animation

Volume 426

The consequences of mitochondrial amyloid β-peptide in Alzheimer's disease
K. E. A. Muirhead, E. Borger, L. Aitken, S. J. Conway and F. J. Gunn‑Moore..........255‑270
Published on the Internet 24 February 2010, doi:10.1042/BJ20091941
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Rho GTPases: regulation of cell polarity and growth in yeasts
P. Perez and S. A. Rincón..........243‑253
Published on the Internet 24 February 2010, doi:10.1042/BJ20091823
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Reflections on studies of gene expression in aneuploids
J. A. Birchler..........119‑123
Published on the Internet 9 February 2010, doi:10.1042/BJ20091617
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Poly(A)-binding protein (PABP): a common viral target
R. W. P. Smith and N. K. Gray..........1‑12
Published on the Internet 27 January 2010, doi:10.1042/BJ20091571
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Volume 425

Taking the plunge: integrating structural, enzymatic and computational insights into a unified model for membrane-immersed rhomboid proteolysis
S. Urban..........501‑512
Published on the Internet 15 January 2010, doi:10.1042/BJ20090861
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Structure and function of the GINS complex, a key component of the eukaryotic replisome
S. A. MacNeill..........489‑500
Published on the Internet 15 January 2010, doi:10.1042/BJ20091531
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Two-step and one-step secretion mechanisms in Gram-negative bacteria: contrasting the type IV secretion system and the chaperone-usher pathway of pilus biogenesis
A. T. Rêgo, V. Chandran and G. Waksman..........475‑488
Published on the Internet 15 January 2010, doi:10.1042/BJ20091518
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The emerging importance of group II PAKs
C. M. Wells and G. E. Jones..........465‑473
Published on the Internet 15 January 2010, doi:10.1042/BJ20091173
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Towards the molecular mechanism of respiratory complex I
J. Hirst..........327‑339
Published on the Internet 23 December 2009, doi:10.1042/BJ20091382
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Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling
A. G. Cox, C. C. Winterbourn and M. B. Hampton..........313‑325
Published on the Internet 23 December 2009, doi:10.1042/BJ20091541
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The N-terminal RASSF family: a new group of Ras-association-domain-containing proteins, with emerging links to cancer formation
V. Sherwood, A. Recino, A. Jeffries, A. Ward and A. D. Chalmers..........303‑311
Published on the Internet 23 December 2009, doi:10.1042/BJ20091318
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The author has paid for access to this article to be freely availableRegulation of mRNA cap methylation
V. H. Cowling..........295‑302
Published on the Internet 23 December 2009, doi:10.1042/BJ20091352
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Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation
P. Cohen..........53‑54
Published on the Internet 14 December 2009, doi:10.1042/BJ20091428
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Transcriptional and post-translational regulation of adiponectin
M. Liu and F. Liu..........41‑52
Published on the Internet 14 December 2009, doi:10.1042/BJ20091045
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Breaking the code: Ca2+ sensors in plant signalling
T. A. DeFalco, K. W. Bender and W. A. Snedden..........27‑40
Published on the Internet 14 December 2009, doi:10.1042/BJ20091147
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Molecular mechanisms of metabolic regulation by insulin in Drosophila
A. A. Teleman..........13‑26
Published on the Internet 14 December 2009, doi:10.1042/BJ20091181
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‘Unknown’ proteins and ‘orphan’ enzymes: the missing half of the engineering parts list – and how to find it
A. D. Hanson, A. Pribat, J. C. Waller and  V. de Crécy‑Lagard..........1‑11
Published on the Internet 14 December 2009, doi:10.1042/BJ20091328
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Volume 424

The author has paid for access to this article to be freely availableCalling International Rescue: knowledge lost in literature and data landslide!
T. K. Attwood, D. B. Kell, P. McDermott, J. Marsh, S. R. Pettifer and D. Thorne..........317‑333
Published on the Internet 10 December 2009, doi:10.1042/BJ20091474
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Volume 423

The hepatitis C virus and its hepatic environment: a toxic but finely tuned partnership
M. Perrault and E.‑I. Pécheur..........303‑314
Published on the Internet 12 October 2009, doi:10.1042/BJ20091000
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Mechanisms of double-strand break repair in somatic mammalian cells
A. J. Hartlerode and R. Scully..........157‑168
Published on the Internet 25 September 2009, doi:10.1042/BJ20090942
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The plant endoplasmic reticulum: a cell-wide web
I. A. Sparkes, L. Frigerio, N. Tolley and C. Hawes..........145‑155
Published on the Internet 25 September 2009, doi:10.1042/BJ20091113
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The author has paid for access to this article to be freely availableRole of plant glyoxylate reductases during stress: a hypothesis
W. L. Allan, S. M. Clark, G. J. Hoover and B. J. Shelp..........15‑22
Published on the Internet 14 September 2009, doi:10.1042/BJ20090826
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Cholesterol, regulated exocytosis and the physiological fusion machine
M. A. Churchward and J. R. Coorssen..........1‑14
Published on the Internet 14 September 2009, doi:10.1042/BJ20090969
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Volume 422

Molecular biology, genetics and biochemistry of the repulsive guidance molecule family
C. J. Severyn, U. Shinde and P. Rotwein..........393‑403
Published on the Internet 27 August 2009, doi:10.1042/BJ20090978
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Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: a cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation
V. I. Bunik and A. R. Fernie..........405‑421
Published on the Internet 27 August 2009, doi:10.1042/BJ20090722
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Use of single-molecule spectroscopy to tackle fundamental problems in biochemistry: using studies on purple bacterial antenna complexes as an example
R. J. Cogdell and J.  Köhler..........193‑205
Published on the Internet 13 August 2009, doi:10.1042/BJ20090674
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Regulation and function of selenoproteins in human disease
F. P. Bellinger, A. V. Raman, M. A. Reeves and M. J. Berry..........11‑22
Published on the Internet 29 July 2009, doi:10.1042/BJ20090219
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Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins
S. Carpenter and L. A. J. O'Neill..........1‑10
Published on the Internet 29 July 2009, doi:10.1042/BJ20090616
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Volume 421

Polyamine catabolism and disease
R. A. Casero and A. E. Pegg..........323‑338
Published on the Internet 15 July 2009, doi:10.1042/BJ20090598
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The author has paid for access to this article to be freely availableFunction and regulation of phospholipid signalling in plants
H. W. Xue, X. Chen and Y. Mei..........145‑156
Published on the Internet 26 June 2009, doi:10.1042/BJ20090300
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At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis
R. T. Youker, U. Shinde, R. Day and G. Thomas..........1‑15
Published on the Internet 12 June 2009, doi:10.1042/BJ20081016
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Volume 420

Anaplastic lymphoma kinase: signalling in development and disease
R. H. Palmer, E. Vernersson, C. Grabbe and B. Hallberg..........345‑361
Published on the Internet 27 May 2009, doi:10.1042/BJ20090387
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Lateral organization of membrane proteins: tetraspanins spin their web
S. Charrin, F. le Naour, O. Silvie, Pierre‑E. Milhiet, C. Boucheix and E. Rubinstein..........133‑154
Published on the Internet 13 May 2009, doi:10.1042/BJ20082422
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Pathogen recognition in the innate immune response
H. Kumar, T. Kawai and S. Akira..........1–16
Published on the Internet 28 April 2009, doi:10.1042/BJ20090272
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Volume 419

The intracellular interactions of the L1 family of cell adhesion molecules
L.R. Herron, M. Hill, F. Davey and F.J. Gunn-Moore..........519–531
Published on the Internet 14 April 2009, doi:10.1042/BJ20082284
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Connexin43 phosphorylation: structural changes and biological effects
J.L. Solan and P.D. Lampe..........261–272
Published on the Internet 27 March 2009, doi:10.1042/BJ20082319
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Snf1-related protein kinases (SnRKs) act within an intricate network that links metabolic and stress signalling in plants
N.G. Halford and S.J. Hey..........247–259
Published on the Internet 27 March 2009, doi:10.1042/BJ20082408
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The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease
L.M. Ooms, K.A. Horan, P. Rahman, G. Seaton, R. Gurung, D.S. Kethesparan and C.A. Mitchell..........29–49
Published on the Internet 13 March 2009, doi:10.1042/BJ20081673
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Genomic and structural aspects of protein evolution
C. Chothia and J. Gough..........15–28
Published on the Internet 13 March 2009, doi:10.1042/BJ20090122
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Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function
S.K. Dove, K. Dong, T. Kobayashi, F.K. Williams and R.H. Michell..........1–13
Published on the Internet 13 March 2009, doi:10.1042/BJ20081950
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Volume 418

Signal co-operation between integrins and other receptor systems
C.H. Streuli and N. Akhtar..........491–506
Published on the Internet 25 February 2009, doi:10.1042/BJ20081948
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Dual-specificity phosphatases: critical regulators with diverse cellular targets
K.I. Patterson, T. Brummer, P.M. O'Brien and R.J. Daly..........475–489
Published on the Internet 25 February 2009, doi:10.1042/BJ20082234
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AMPK and the biochemistry of exercise: implications for human health and disease
E.A. Richter and N.B. Ruderman..........261–275
Published on the Internet 11 February 2009, doi:10.1042/BJ20082055
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Out, in and back again: PtdIns(4,5)P2 regulates cadherin trafficking in epithelial morphogenesis
N.J. Schill and R.A. Anderson..........247–260
Published on the Internet 11 February 2009, doi:10.1042/BJ20081844
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Phosphatidylinositol metabolism and membrane fusion
D. Poccia and B. Larijani..........233–246
Published on the Internet 11 February 2009, doi:10.1042/BJ20082105
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The second green revolution? Production of plant-based biodegradable plastics
B.P. Mooney..........219–232
Published on the Internet 11 February 2009, doi:10.1042/BJ20081769
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Mechanisms of chemokine and antigen-dependent T-lymphocyte navigation
S.G. Ward and F.M. Marelli-Berg..........13–27
Published on the Internet 28 January 2009, doi:10.1042/BJ20081969
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Insulin/IGF-like signalling, the central nervous system and aging
S. Broughton and L. Partridge..........1–12
Published on the Internet 28 January 2009, doi:10.1042/BJ20082102
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Volume 417

Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum
M. Michalak, J. Groenendyk, E. Szabo, L.I. Gold and M. Opas..........651–666
Published on the Internet 16 January 2009, doi:10.1042/BJ20081847
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Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
B.L. Mahaney, K. Meek and S.P. Lees-Miller..........639–650
Published on the Internet 16 January 2009, doi:10.1042/BJ20080413
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The origin, evolution and structure of the protein world
G. Caetano-Anollés, M. Wang, D. Caetano-Anollés and J.E. Mittenthal..........621–637
Published on the Internet 16 January 2009, doi:10.1042/BJ20082063
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Bicarbonate transport in cell physiology and disease
E. Cordat and J.R. Casey..........423–439
Published on the Internet 23 December 2008, doi:10.1042/BJ20081634
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The TGF-β, PI3K/Akt and PTEN pathways: established and proposed biochemical integration in prostate cancer
S.J. Assinder, Q. Dong, Z. Kovacevic and D.R. Richardson..........411–421
Published on the Internet 23 December 2008, doi:10.1042/BJ20081610
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Evolution of protein phosphatases in plants and animals
G.B.G. Moorhead, V. De Wever, G. Templeton and D. Kerk..........401–409
Published on the Internet 23 December 2008, doi:10.1042/BJ20081986
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Darwin, Dover, ‘Intelligent Design’ and textbooks
K. Padian and N. Matzke..........29–42
Published on the Internet 12 December 2008, doi:10.1042/BJ20081534
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The SR protein family of splicing factors: master regulators of gene expression
J.C. Long and J.F. Caceres..........15–27
Published on the Internet 12 December 2008, doi:10.1042/BJ20081501
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The author has paid for access to this article to be freely availbleHow mitochondria produce reactive oxygen species
M.P. Murphy..........1–13
Published on the Internet 12 December 2008, doi:10.1042/BJ20081386
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