Supplementary Online Data
The Biochemical Journal publishes
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Volume 452
Ebola virus VP35 induces high-level production of recombinant TPL-2–ABIN-2–NF-κB1 p105 complex in co-transfected HEK-293 cells
Thorsten Gantke, Sabrina Boussouf, Julia Janzen, Nicholas A. Morrice, Steven Howell, Elke Mühlberger and Steven C. Ley..........359‑365
Published as BJ Immediate Publication 4 April 2013, doi:10.1042/BJ20121873
Crystal structures of glycoside hydrolase family 3 β-glucosidase 1 from Aspergillus aculeatus
Kentaro Suzuki, Jun‑Ichi Sumitani, Young‑Woo Nam, Toru Nishimaki, Shuji Tani, Takayoshi Wakagi, Takashi Kawaguchi and Shinya Fushinobu..........211‑221
Published as BJ Immediate Publication 28 March 2013, doi:10.1042/BJ20130054

Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing
Judith Reeks, Richard D. Sokolowski, Shirley Graham, Huanting Liu, James H. Naismith and Malcolm F. White..........223‑230
Published as BJ Immediate Publication 25 March 2013, doi:10.1042/BJ20130269
Mitochondrial respiratory chain complex I is inactivated by NADPH oxidase Nox4
Rafał Kozieł, Haymo Pircher, Manuela Kratochwil, Barbara Lener, Martin Hermann, Norbert A. Dencher and Pidder Jansen‑Dürr..........231‑239
Published as BJ Immediate Publication 20 March 2013, doi:10.1042/BJ20121778
Single-strand promoter traps for bacterial RNA polymerase
Danil Pupov, Daria Esyunina, Andrey Feklistov and Andrey Kulbachinskiy..........241‑248
Published as BJ Immediate Publication 22 March 2013, doi:10.1042/BJ20130069
TgrC1 mediates cell–cell adhesion by interacting with TgrB1 via mutual IPT/TIG domains during development of Dictyostelium discoideum
Gong Chen, Jun Wang, Xiaoqun Xu, Xiangfu Wu, Ruihan Piao and Chi‑Hung Siu..........259‑269
Published as BJ Immediate Publication 12 March 2013, doi:10.1042/BJ20121674
Proteolytic activation of prochemerin by kallikrein 7 breaks an ionic linkage and results in C-terminal rearrangement
Stephan Schultz, Anja Saalbach, John T. Heiker, Rene Meier, Tristan Zellmann, Jan C. Simon and Annette G. Beck‑Sickinger..........271‑280
Published as BJ Immediate Publication 18 March 2013, doi:10.1042/BJ20121880
microRNA-138 plays a role in hypoxic pulmonary vascular remodelling by targeting Mst1
Shanshan Li, Yajuan Ran, Dandan Zhang, Jianguo Chen, Shuzhen Li and Daling Zhu..........281‑291
Published as BJ Immediate Publication 13 March 2013, doi:10.1042/BJ20120680
The muscarinic M3 acetylcholine receptor exists as two differently sized complexes at the plasma membrane
Suparna Patowary, Elisa Alvarez‑Curto, Tian‑Rui Xu, Jessica D. Holz, Julie A. Oliver, Graeme Milligan and Valerică Raicu..........303‑312
Published as BJ Immediate Publication 25 March 2013, doi:10.1042/BJ20121902
A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation
Carolyn Bentley, Stefanie S. Jurinka, Noelyn M. Kljavin, Steffan Vartanian, Sree R. Ramani, Lino C. Gonzalez, Kebing Yu, Zora Modrusan, Pan Du, Richard Bourgon, Richard M. Neve and David Stokoe..........313‑320
Published as BJ Immediate Publication 18 March 2013, doi:10.1042/BJ20121578
The COUP-TFII variant lacking a DNA-binding domain inhibits the activation of the Cyp7a1 promoter through physical interaction with COUP-TFII
Tomoko Yamazaki, Jun‑ichi Suehiro, Hideki Miyazaki, Takashi Minami, Tatsuhiki Kodama, Kohei Miyazono and Tetsuro Watabe..........345‑357
Published as BJ Immediate Publication 5 March 2013, doi:10.1042/BJ20121200
Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits
Naeem Shafqat, Joao R. C. Muniz, Ewa S. Pilka, Evangelos Papagrigoriou, Frank von Delft, Udo Oppermann and Wyatt W. Yue..........27‑36
Published as BJ Immediate Publication 20 February 2013, doi:10.1042/BJ20121580
Seipin differentially regulates lipogenesis and adipogenesis through a conserved core sequence and an evolutionarily acquired C-terminus
Wulin Yang, Shermaine Thein, Xiangxiang Guo, Feng Xu, Byrappa Venkatesh, Shigeki Sugii, George K. Radda and Weiping Han..........37‑44
Published as BJ Immediate Publication 4 March 2013, doi:10.1042/BJ20121870
mRNA encoding WAVE–Arp2/3-associated proteins is co-localized with foci of active protein synthesis at the leading edge of MRC5 fibroblasts during cell migration
Mark Willett, Michele Brocard, Hilary J. Pollard and Simon J. Morley..........45‑55
Published as BJ Immediate Publication 4 March 2013, doi:10.1042/BJ20121803

Characterization of a pre-export enzyme–chaperone complex on the twin-arginine transport pathway
Jennifer M. Dow, Frank Gabel, Frank Sargent and Tracy Palmer..........57‑66
Published as BJ Immediate Publication 1 March 2013, doi:10.1042/BJ20121832
Nuclear export factor 3 is involved in regulating the expression of TGF-β3 in an mRNA export activity-independent manner in mouse Sertoli cells
Yimeng Yin, Guishuan Wang, Ning Liang, Huijuan Zhang, Zhimin Liu, Wenqing Li and Fei Sun..........67‑78
Published as BJ Immediate Publication 25 February 2013, doi:10.1042/BJ20121006
FSL-61 is a 6-nitroquinolone fluorogenic probe for one-electron reductases in hypoxic cells
Jiechuang Su, Christopher P. Guise and William R. Wilson..........79‑86
Published as BJ Immediate Publication 12 March 2013, doi:10.1042/BJ20121695
Proteomic analysis and molecular modelling characterize the iron-regulatory protein haemojuvelin/repulsive guidance molecule c
Mahta Nili, Larry David, Johannes Elferich, Ujwal Shinde and Peter Rotwein..........87‑95
Published as BJ Immediate Publication 6 March 2013, doi:10.1042/BJ20121845
ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins
Camilla Fröhlich, Marie Klitgaard, Julie B. Noer, Alexander Kotzsch, Camilla Nehammer, Pauliina Kronqvist, Jens Berthelsen, Carl Blobel, Marie Kveiborg, Reidar Albrechtsen and Ulla M. Wewer..........97‑109
Published as BJ Immediate Publication 5 March 2013, doi:10.1042/BJ20121558
BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins
Levi J. Beverly, Lauren A. Howell, Maria Hernandez‑Corbacho, Lavona Casson, Jerry E. Chipuk and Leah J. Siskind..........111‑119
Published as BJ Immediate Publication 12 March 2013, doi:10.1042/BJ20130147
Pyrvinium pamoate does not activate protein kinase CK1, but promotes Akt/PKB down-regulation and GSK3 activation
Andrea Venerando, Cristina Girardi, Maria Ruzzene and Lorenzo A. Pinna..........131‑137
Published as BJ Immediate Publication 26 February 2013, doi:10.1042/BJ20121140
FGF-2 prevents cancer cells from ER stress-mediated apoptosis via enhancing proteasome-mediated Nck degradation
Bin Li, Zhenjun Pi, Lei Liu, Bi Zhang, Xiang Huang, Ping Hu, Eric Chevet, Ping Yi and Jianfeng Liu..........139‑145
Published as BJ Immediate Publication 1 March 2013, doi:10.1042/BJ20121671
Protein recognition of the S23906-1–DNA adduct by nuclear proteins: direct involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
Gaëlle Lenglet, Sabine Depauw, Denise Mendy and Marie‑Hélène David‑Cordonnier..........147‑159
Published as BJ Immediate Publication 14 February 2013, doi:10.1042/BJ20120860
Protein disulfide-isomerase interacts with soluble guanylyl cyclase via a redox-based mechanism and modulates its activity
Erin J. Heckler, Pierre‑Antoine Crassous, Padmamalini Baskaran and Annie Beuve..........161‑169
Published as BJ Immediate Publication 11 March 2013, doi:10.1042/BJ20130298
Volume 451

Exploring the structure and function of
Thermotoga maritima CorA reveals the mechanism of gating and ion selectivity in Co
2+/Mg
2+ transport
Nurhuda Nordin, Albert Guskov, Terri Phua, Newsha Sahaf, Yu Xia, Siyan Lu, Hojjat Eshaghi and Said Eshaghi..........365‑374
Published as BJ Immediate Publication 21 February 2013, doi:10.1042/BJ20121745
PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress
Joshua K. Salabei, Timothy D. Cummins, Mahavir Singh, Steven P. Jones, Aruni Bhatnagar and Bradford G. Hill..........375‑388
Published as BJ Immediate Publication 20 February 2013, doi:10.1042/BJ20121344
Unexpected weak magnetic exchange coupling between haem and non-haem iron in the catalytic site of nitric oxide reductase (NorBC) from Paracoccus denitrificans
Jessica H. Van Wonderen, Vasily S. Oganesyan, Nicholas J. Watmough, David J. Richardson, Andrew J. Thomson and Myles R. Cheesman..........389‑394
Published as BJ Immediate Publication 20 February 2013, doi:10.1042/BJ20121406
ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours
M. Luisa Campos, Víctor J. Sánchez‑Arévalo Lobo, Annie Rodolosse, Cara J. Gottardi, Andrea Mafficini, Stefania Beghelli, Maria Scardoni, Claudio Bassi, Aldo Scarpa and Francisco X. Real..........395‑405
Published as BJ Immediate Publication 22 January 2013, doi:10.1042/BJ20120873
Structure–function analysis of full-length midkine reveals novel residues important for heparin binding and zebrafish embryogenesis
Jackwee Lim, Sheng Yao, Martin Graf, Christoph Winkler and Daiwen Yang..........407‑415
Published as BJ Immediate Publication 18 February 2013, doi:10.1042/BJ20121622
Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency
Jian‑Xu Li, Xin Fang, Qin Zhao, Ju‑Xin Ruan, Chang‑Qing Yang, Ling‑Jian Wang, David J. Miller, Juan A. Faraldos, Rudolf K. Allemann, Xiao‑Ya Chen and Peng Zhang..........417‑426
Published as BJ Immediate Publication 26 February 2013, doi:10.1042/BJ20130041
The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system
Sam Strickson, David G. Campbell, Christoph H. Emmerich, Axel Knebel, Lorna Plater, Maria Stella Ritorto, Natalia Shpiro and Philip Cohen..........427‑437
Published as BJ Immediate Publication 27 February 2013, doi:10.1042/BJ20121651
Prediction of hammerhead ribozyme intracellular activity with the catalytic core fingerprint
Marta Magdalena Gabryelska, Eliza Wyszko, Maciej Szymański, Mariusz Popenda and Jan Barciszewski..........439‑451
Published as BJ Immediate Publication 19 February 2013, doi:10.1042/BJ20121761

DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbα
Claudia C. S. Chini, Carlos Escande, Veronica Nin and Eduardo N. Chini..........453‑461
Published as BJ Immediate Publication 12 February 2013, doi:10.1042/BJ20121085
Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels
Pilar de la Peña, Angeles Machín, Jorge Fernández‑Trillo, Pedro Domínguez and Francisco Barros..........463‑474
Published as BJ Immediate Publication 18 February 2013, doi:10.1042/BJ20121717
Zinc-dependent lysosomal enlargement in TRPML1-deficient cells involves MTF-1 transcription factor and ZnT4 (Slc30a4) transporter
Ira Kukic, Jeffrey K. Lee, Jessica Coblentz, Shannon L. Kelleher and Kirill Kiselyov..........155‑163
Published as BJ Immediate Publication 1 February 2013, doi:10.1042/BJ20121506
Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1
Nicholas T. Redpath, Yibin Xu, Nicholas J. Wilson, Louis J. Fabri, Manuel Baca, Arna E. Andrews, Hal Braley, Ping Lu, Cheryl Ireland, Robin E. Ernst, Andrea Woods, Gail Forrest, Zhiqiang An, Dennis M. Zaller, William R. Strohl, Cindy S. Luo, Peter E. Czabotar, Thomas P. J. Garrett, Douglas J. Hilton, Andrew D. Nash, Jian‑Guo Zhang and Nicos A. Nicola..........165‑175
Published as BJ Immediate Publication 6 February 2013, doi:10.1042/BJ20121819

Subtype-selective regulation of IP
3 receptors by thimerosal via cysteine residues within the IP
3-binding core and suppressor domain
Samir A. Khan, Ana M. Rossi, Andrew M. Riley, Barry V. L. Potter and Colin W. Taylor..........177‑184
Published as BJ Immediate Publication 2 January 2013, doi:10.1042/BJ20121600

The P-body component USP52/PAN2 is a novel regulator of
HIF1A mRNA stability
John S. Bett, Adel F. M. Ibrahim, Amit K. Garg, Van Kelly, Patrick Pedrioli, Sonia Rocha and Ronald T. Hay..........185‑194
Published as BJ Immediate Publication 11 February 2013, doi:10.1042/BJ20130026
Interaction of NuMA protein with the kinesin Eg5: its possible role in bipolar spindle assembly and chromosome alignment
Yuko Iwakiri, Sachiko Kamakura, Junya Hayase and Hideki Sumimoto..........195‑204
Published as BJ Immediate Publication 1 February 2013, doi:10.1042/BJ20121447
Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity
Emily Golden, Rachel Paterson, Wan Jun Tie, Anandhi Anandan, Gavin Flematti, Gianluca Molla, Elena Rosini, Loredano Pollegioni and Alice Vrielink..........217‑226
Published as BJ Immediate Publication 4 February 2013, doi:10.1042/BJ20121715
Incretin-stimulated interaction between β-cell Kv1.5 and Kvβ2 channel proteins involves acetylation/deacetylation by CBP/SirT1
Su‑Jin Kim, Ziliang Ao, Garth Warnock and Christopher H. S. McIntosh..........227‑234
Published as BJ Immediate Publication 7 February 2013, doi:10.1042/BJ20121669

V101L of human formyl peptide receptor 1 (FPR1) increases receptor affinity and augments the antagonism mediated by cyclosporins
Caihong Zhou, Yan Zhou, Jia Wang, Yang Feng, Haonan Wang, Jinglun Xue, Yani Chen, Richard D. Ye and Ming‑Wei Wang..........245‑255
Published as BJ Immediate Publication 4 February 2013, doi:10.1042/BJ20121839
Eukaryotic initiation factor 5A dephosphorylation is required for translational arrest in stationary phase cells
Janete Chung, Antonio A. Rocha, Renata R. Tonelli, Beatriz A. Castilho and Sergio Schenkman..........257‑267
Published as BJ Immediate Publication 31 January 2013, doi:10.1042/BJ20121553
Entamoeba histolytica: identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example
Sarah Schlosser, David Leitsch and Michael Duchêne..........277‑288
Published as BJ Immediate Publication 11 February 2013, doi:10.1042/BJ20121798
Solution structure, dynamics and binding studies of a family 11 carbohydrate-binding module from Clostridium thermocellum (CtCBM11)
Aldino Viegas, João Sardinha, Filipe Freire, Daniel F. Duarte, Ana L. Carvalho, Carlos M. G. A. Fontes, Maria J. Romão, Anjos L. Macedo and Eurico J. Cabrita..........289‑300
Published as BJ Immediate Publication 29 January 2013, doi:10.1042/BJ20120627
Prohepcidin binds to the HAMP promoter and autoregulates its own expression
Edina Pandur, Katalin Sipos, László Grama, Judit Nagy, Viktor S. Poór, György Sétáló, Attila Miseta and Zsuzsanna Fekete..........301‑311
Published as BJ Immediate Publication 7 February 2013, doi:10.1042/BJ20121466
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery
Yinghong Gao, Stephen P. Davies, Martin Augustin, Anna Woodward, Umesh A. Patel, Robert Kovelman and Kevin J. Harvey..........313‑328
Published as BJ Immediate Publication 12 February 2013, doi:10.1042/BJ20121418
Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes
Svend Kjær, Mark Linch, Andrew Purkiss, Brenda Kostelecky, Phillip P. Knowles, Carine Rosse, Philippe Riou, Christelle Soudy, Sarah Kaye, Bhavisha Patel, Erika Soriano, Judith Murray‑Rust, Caroline Barton, Christian Dillon, Jon Roffey, Peter J. Parker and Neil Q. McDonald..........329‑342
Published as BJ Immediate Publication 18 February 2013, doi:10.1042/BJ20121871
The CUL3–KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction
- Akihito Ohta, Frances‑Rose Schumacher, Youcef Mehellou, Clare Johnson, Axel Knebel, Thomas J. Macartney, Nicola T. Wood, Dario R. Alessi and Thimo Kurz..........111‑122
- Published as BJ Immediate Publication 6 February 2013, doi:10.1042/BJ20121903
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Abstract | Full text HTML | Full text PDF | Online Data
Saltatory formation, sliding and dissolution of ER–PM junctions in migrating cancer cells
- Hayley Dingsdale, Emmanuel Okeke, Muhammad Awais, Lee Haynes, David N. Criddle, Robert Sutton and Alexei V. Tepikin..........25‑32
- Published as BJ Immediate Publication 16 January 2013, doi:10.1042/BJ20121864
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Abstract | Full text HTML | Full text PDF | Online Data | Multimedia
- Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ)
- Ghazi M. Rahman, Sreejesh Shanker, Nancy E. Lewin, Noemi Kedei, Colin S. Hill, B. V. Venkataram Prasad, Peter M. Blumberg and Joydip Das..........33‑44
- Published as BJ Immediate Publication 4 January 2013, doi:10.1042/BJ20121307
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Abstract | Full text HTML | Full text PDF | Online Data
- The serine/threonine phosphatase PPM1B (PP2Cβ) selectively modulates PPARγ activity
- Ismayil Tasdelen, Olivier van Beekum, Olena Gorbenko, Veerle Fleskens, Niels J. F. van den Broek, Arjen Koppen, Nicole Hamers, Ruud Berger, Paul J. Coffer, Arjan B. Brenkman and Eric Kalkhoven..........45‑53
- Published as BJ Immediate Publication 15 January 2013, doi:10.1042/BJ20121113
-
Abstract | Full text HTML | Full text PDF | Online Data
- Mechanistic studies of FosB: a divalent-metal-dependent bacillithiol-S-transferase that mediates fosfomycin resistance in Staphylococcus aureus
- Alexandra A. Roberts, Sunil V. Sharma, Andrew W. Strankman, Shayla R. Duran, Mamta Rawat and Chris J. Hamilton..........69‑79
- Published as BJ Immediate Publication 21 December 2012, doi:10.1042/BJ20121541
-
Abstract | Full text HTML | Full text PDF | Online Data
- AdE-1, a new inotropic Na+ channel toxin from Aiptasia diaphana, is similar to, yet distinct from, known anemone Na+ channel toxins
- Nir Nesher, Eli Shapira, Daniel Sher, Yehu Moran, Liora Tsveyer, Ana Luiza Turchetti‑Maia, Michal Horowitz, Binyamin Hochner and Eliahu Zlotkin..........81‑90
- Published as BJ Immediate Publication 28 January 2013, doi:10.1042/BJ20121623
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Abstract | Full text HTML | Full text PDF | Online Data
The mannose 6-phosphate-binding sites of M6P/IGF2R determine its capacity to suppress matrix invasion by squamous cell carcinoma cells
- Olivia C. Probst, Evren Karayel, Nicole Schida, Elisabeth Nimmerfall, Elisabeth Hehenberger, Verena Puxbaum and Lukas Mach..........91‑99
- Published as BJ Immediate Publication 25 January 2013, doi:10.1042/BJ20121422
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Abstract | Full text HTML | Full text PDF | Online Data
- HER2 stabilizes survivin while concomitantly down-regulating survivin gene transcription by suppressing Notch cleavage
- Ji‑hyun Ju, Wonseok Yang, Sunhwa Oh, KeeSoo Nam, Kyung‑min Lee, Dong‑young Noh and Incheol Shin..........123‑134
- Published as BJ Immediate Publication 17 January 2013, doi:10.1042/BJ20121716
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Abstract | Full text HTML | Full text PDF | Online Data
Volume 450
Exploring the sequence–structure relationship for amyloid peptides
- Kyle L. Morris, Alison Rodger, Matthew R. Hicks, Maya Debulpaep, Joost Schymkowitz, Frederic Rousseau and Louise C. Serpell..........275‑283
- Published as BJ Immediate Publication 20 December 2012, doi:10.1042/BJ20121773
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Abstract | Full text HTML | Full text PDF | Online Data
- The BH3 mimetic ABT-263 synergizes with the MEK1/2 inhibitor selumetinib/AZD6244 to promote BIM-dependent tumour cell death and inhibit acquired resistance
- Matthew J. Sale and Simon J. Cook..........285‑294
- Published as BJ Immediate Publication 13 December 2012, doi:10.1042/BJ20121212
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Abstract | Full text HTML | Full text PDF | Online Data
- Autoimmune disorder phenotypes in Hvcn1-deficient mice
- Mari Sasaki, Akihiro Tojo, Yoshifumi Okochi, Nana Miyawaki, Daisuke Kamimura, Akihito Yamaguchi, Masaaki Murakami and Yasushi Okamura..........295‑301
- Published as BJ Immediate Publication 12 December 2012, doi:10.1042/BJ20121188
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Abstract | Full text HTML | Full text PDF | Online Data
High-resolution NMR studies of structure and dynamics of human ERp27 indicate extensive interdomain flexibility
- Nader T. Amin, A. Katrine Wallis, Stephen A. Wells, Michelle L. Rowe, Richard A. Williamson, Mark J. Howard and Robert B. Freedman..........321‑332
- Published as BJ Immediate Publication 12 December 2012, doi:10.1042/BJ20121635
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Abstract | Full text HTML | Full text PDF | Online Data
- Pathogenic mutations causing LBSL affect mitochondrial aspartyl-tRNA synthetase in diverse ways
- Laura van Berge, Josta Kevenaar, Emiel Polder, Agnès Gaudry, Catherine Florentz, Marie Sissler, Marjo S. van der Knaap and Gert C. Scheper..........345‑350
- Published as BJ Immediate Publication 10 December 2012, doi:10.1042/BJ20121564
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Abstract | Full text HTML | Full text PDF | Online Data
p90 Ribosomal S6 kinases play a significant role in early gene regulation in the cardiomyocyte response to Gq-protein-coupled receptor stimuli, endothelin-1 and α1-adrenergic receptor agonists
- Emre Amirak, Stephen J. Fuller, Peter H. Sugden and Angela Clerk..........351‑363
- Published as BJ Immediate Publication 10 December 2012, doi:10.1042/BJ20121371
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Abstract | Full text HTML | Full text PDF | Online Data
- Extracellular calcium influx activates adenylate cyclase 1 and potentiates insulin secretion in MIN6 cells
- Tetsuya Kitaguchi, Manami Oya, Yoshiko Wada, Takashi Tsuboi and Atsushi Miyawaki..........365‑373
- Published as BJ Immediate Publication 3 January 2013, doi:10.1042/BJ20121022
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Abstract | Full text HTML | Full text PDF | Online Data
- Misprocessing and functional arrest of microRNAs by miR-Pirate: roles of miR-378 and miR-17
- Zhaoqun Deng, Xiangling Yang, Ling Fang, Zina J. Rutnam and Burton B. Yang..........375‑386
- Published as BJ Immediate Publication 5 December 2012, doi:10.1042/BJ20120722
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Abstract | Full text HTML | Full text PDF | Online Data
- Effects of the lipid environment, cholesterol and bile acids on the function of the purified and reconstituted human ABCG2 protein
- Ágnes Telbisz, Csilla Özvegy‑Laczka, Tamás Hegedűs, András Váradi and Balázs Sarkadi..........387‑395
- Published as BJ Immediate Publication 3 December 2012, doi:10.1042/BJ20121485
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Abstract | Full text HTML | Full text PDF | Online Data
- Identification of an 8-vinyl reductase involved in bacteriochlorophyll biosynthesis in Rhodobacter sphaeroides and evidence for the existence of a third distinct class of the enzyme
- Daniel P. Canniffe, Philip J. Jackson, Sarah Hollingshead, Mark J. Dickman and C. Neil Hunter..........397‑405
- Published as BJ Immediate Publication 19 December 2012, doi:10.1042/BJ20121723
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Abstract | Full text HTML | Full text PDF | Online Data
- Proteomic analysis of Mesembryanthemum crystallinum leaf microsomal fractions finds an imbalance in V-ATPase stoichiometry during the salt-induced transition from C3 to CAM
- Cristian Cosentino, Dario Di Silvestre, Elke Fischer‑Schliebs, Ulrike Homann, Antonella De Palma, Claudio Comunian, Pier Luigi Mauri and Gerhard Thiel..........407‑415
- Published as BJ Immediate Publication 20 December 2012, doi:10.1042/BJ20121087
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Abstract | Full text HTML | Full text PDF | Online Data
Structure and mechanism of the PilF DNA transformation ATPase from Thermus thermophilus
- Richard F. Collins, Darin Hassan, Vijaykumar Karuppiah, Angela Thistlethwaite and Jeremy P. Derrick..........417‑425
- Published as BJ Immediate Publication 20 December 2012, doi:10.1042/BJ20121599
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Abstract | Full text HTML | Full text PDF | Online Data | Multimedia
- Novel configuration of a myosin II transient intermediate analogue revealed by quick-freeze deep-etch replica electron microscopy
- Yoshitaka Kimori, Norio Baba and Eisaku Katayama..........23‑35
- Published as BJ Immediate Publication 5 December 2012, doi:10.1042/BJ20120412
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Abstract | Full text HTML | Full text PDF | Online Data
- Kinetic analysis of Arabidopsis glucosyltransferase UGT74B1 illustrates a general mechanism by which enzymes can escape product inhibition
- Jakub Kopycki, Elizabeth Wieduwild, Janine Kohlschmidt, Wolfgang Brandt, Anna N. Stepanova, Jose M. Alonso, M. Soledade C. Pedras, Steffen Abel and C. Douglas Grubb..........37‑46
- Published as BJ Immediate Publication 15 November 2012, doi:10.1042/BJ20121403
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Abstract | Full text HTML | Full text PDF | Online Data
- Parkinson's disease-associated human P5B-ATPase ATP13A2 increases spermidine uptake
- Diego P. De La Hera, Gerardo R. Corradi, Hugo P. Adamo and Felicitas De Tezanos Pinto..........47‑53
- Published as BJ Immediate Publication 3 December 2012, doi:10.1042/BJ20120739
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Abstract | Full text HTML | Full text PDF | Online Data
- A novel small-molecule screening strategy identifies mitoxantrone as a RhoGTPase inhibitor
- Aurélien Bidaud‑Meynard, Daniela Arma, Said Taouji, Michel Laguerre, Jean Dessolin, Jean Rosenbaum, Eric Chevet and Violaine Moreau..........55‑62
- Published as BJ Immediate Publication 27 November 2012, doi:10.1042/BJ20120572
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Abstract | Full text HTML | Full text PDF | Online Data
- Probing the origins of glutathione biosynthesis through biochemical analysis of glutamate-cysteine ligase and glutathione synthetase from a model photosynthetic prokaryote
- William B. Musgrave, Hankuil Yi, Dustin Kline, Jeffrey C. Cameron, Jonathan Wignes, Sanghamitra Dey, Himadri B. Pakrasi and Joseph M. Jez..........63‑72
- Published as BJ Immediate Publication 21 November 2012, doi:10.1042/BJ20121332
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Abstract | Full text HTML | Full text PDF | Online Data
- Interaction of amphiphysins with AP-1 clathrin adaptors at the membrane
- Sonja Huser, Gregor Suri, Pascal Crottet and Martin Spiess..........73‑83
- Published as BJ Immediate Publication 29 November 2012, doi:10.1042/BJ20121373
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Abstract | Full text HTML | Full text PDF | Online Data
Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region
- Deshun Gong, Fan Yang, Fudong Li, Dandan Qian, Minhao Wu, Zhenhua Shao, Mian Wu, Jihui Wu and Yunyu Shi..........85‑94
- Published as BJ Immediate Publication 28 November 2012, doi:10.1042/BJ20121382
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Abstract | Full text HTML | Full text PDF | Online Data
- The structure and properties of septin 3: a possible missing link in septin filament formation
- Joci N. A. Macedo, Napoleão F. Valadares, Ivo A. Marques, Frederico M. Ferreira, Julio C. P. Damalio, Humberto M. Pereira, Richard C. Garratt and Ana P. U. Araujo..........95‑105
- Published as BJ Immediate Publication 19 November 2012, doi:10.1042/BJ20120851
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- Tumour cells can employ extracellular Ins(1,2,3,4,5,6)P6 and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation
- Sabine Windhorst, Hongying Lin, Christine Blechner, Werner Fanick, Laura Brandt, Maria A. Brehm and Georg W. Mayr..........115‑125
- Published as BJ Immediate Publication 28 November 2012, doi:10.1042/BJ20121524
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Abstract | Full text HTML | Full text PDF | Online Data
- Crystal structure of hexanoyl-CoA bound to β-ketoacyl reductase FabG4 of Mycobacterium tuberculosis
- Debajyoti Dutta, Sudipta Bhattacharyya, Amlan Roychowdhury, Rupam Biswas and Amit Kumar Das..........127‑139
- Published as BJ Immediate Publication 19 November 2012, doi:10.1042/BJ20121107
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- Metal insertion into the molybdenum cofactor: product–substrate channelling demonstrates the functional origin of domain fusion in gephyrin
- Abdel A. Belaidi and Guenter Schwarz..........149‑157
- Published as BJ Immediate Publication 20 November 2012, doi:10.1042/BJ20121078
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- Biochemical characterization of Plasmodium falciparum CTP:phosphoethanolamine cytidylyltransferase shows that only one of the two cytidylyltransferase domains is active
- Sweta Maheshwari, Marina Lavigne, Alicia Contet, Blandine Alberge, Emilie Pihan, Clemens Kocken, Kai Wengelnik, Dominique Douguet, Henri Vial and Rachel Cerdan..........159‑167
- Published as BJ Immediate Publication 30 November 2012, doi:10.1042/BJ20121480
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Abstract | Full text HTML | Full text PDF | Online Data
- The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function
- Veena Coothankandaswamy, Selvakumar Elangovan, Nagendra Singh, Puttur D. Prasad, Muthusamy Thangaraju and Vadivel Ganapathy..........169‑178
- Published as BJ Immediate Publication 20 November 2012, doi:10.1042/BJ20121248
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Abstract | Full text HTML | Full text PDF | Online Data
- Identification and properties of a novel variant of NBC4 (Na+/HCO3− co-transporter 4) that is predominantly expressed in the choroid plexus
- Hidekazu Fukuda, Taku Hirata, Nobuhiro Nakamura, Akira Kato, Katsumasa Kawahara, Shigeo Wakabayashi, Min‑Hwang Chang, Michael F. Romero and Shigehisa Hirose..........179‑187
- Published as BJ Immediate Publication 4 December 2012, doi:10.1042/BJ20121515
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- Differential configurations involving binding of USF transcription factors and Twist1 regulate Alx3 promoter activity in mesenchymal and pancreatic cells
- Patricia García‑Sanz, Antonio Fernández‑Pérez and Mario Vallejo..........199‑208
- Published as BJ Immediate Publication 27 November 2012, doi:10.1042/BJ20120962
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Abstract | Full text HTML | Full text PDF | Online Data
- Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes
- Zoran Radić, Trevor Dale, Zrinka Kovarik, Suzana Berend, Edzna Garcia, Limin Zhang, Gabriel Amitai, Carol Green, Božica Radić, Brendan M. Duggan, Dariush Ajami, Julius Rebek and Palmer Taylor..........231‑242
- Published as BJ Immediate Publication 6 December 2012, doi:10.1042/BJ20121612
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- Human cytoplasmic ProX edits mischarged tRNAPro with amino acid but not tRNA specificity
- Liang‑Liang Ruan, Xiao‑Long Zhou, Min Tan and En‑Duo Wang..........243‑252
- Published as BJ Immediate Publication 5 December 2012, doi:10.1042/BJ20121493
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Volume 449
- Regulation of adipogenesis by cytoskeleton remodelling is facilitated by acetyltransferase MEC-17-dependent acetylation of α-tubulin
- Wulin Yang, Xiangxiang Guo, Shermaine Thein, Feng Xu, Shigeki Sugii, Peter W. Baas, George K. Radda and Weiping Han..........605‑612
- Published as BJ Immediate Publication 5 November 2012, doi:10.1042/BJ20121121
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Abstract | Full text HTML | Full text PDF | Online Data | Multimedia
- The CARD plays a critical role in ASC foci formation and inflammasome signalling
- Martina Proell, Motti Gerlic, Peter D. Mace, John C. Reed and Stefan J. Riedl..........613‑621
- Published as BJ Immediate Publication 31 October 2012, doi:10.1042/BJ20121198
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- ADP-ribose polymer depletion leads to nuclear Ctcf re-localization and chromatin rearrangement1
- Tiziana Guastafierro, Angela Catizone, Roberta Calabrese, Michele Zampieri, Oliviano Martella, Maria Giulia Bacalini, Anna Reale, Maria Di Girolamo, Margherita Miccheli, Dawn Farrar, Elena Klenova, Fabio Ciccarone and Paola Caiafa..........623‑630
- Published as BJ Immediate Publication 2 November 2012, doi:10.1042/BJ20121429
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- Structure and function of the PorB porin from disseminating Neisseria gonorrhoeae
- Kornelius Zeth, Vera Kozjak‑Pavlovic, Michaela Faulstich, Martin Fraunholz, Robert Hurwitz, Oliver Kepp and Thomas Rudel..........631‑642
- Published as BJ Immediate Publication 25 October 2012, doi:10.1042/BJ20121025
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Abstract | Full text HTML | Full text PDF | Online Data
- Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins
- Tamara D. Skene‑Arnold, Hue Anh Luu, R. Glen Uhrig, Veerle De Wever, Mhairi Nimick, Jason Maynes, Andrea Fong, Michael N. G. James, Laura Trinkle‑Mulcahy, Greg B. Moorhead and Charles F. B. Holmes..........649‑659
- Published as BJ Immediate Publication 23 October 2012, doi:10.1042/BJ20120506
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Abstract | Full text HTML | Full text PDF | Online Data
- Sphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteins
- K. Alexa Orr Gandy, Daniel Canals, Mohamad Adada, Masayuki Wada, Patrick Roddy, Ashley J. Snider, Yusuf A. Hannun and Lina M. Obeid..........661‑672
- Published as BJ Immediate Publication 29 October 2012, doi:10.1042/BJ20120213
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Rfa2 is specifically dephosphorylated by Pph3 in Candida albicans
- Haitao Wang, Jiaxin Gao, Ada Hang‑Heng Wong, Kangdi Hu, Wanjie Li, Yue Wang and Jianli Sang..........673‑681
- Published as BJ Immediate Publication 9 November 2012, doi:10.1042/BJ20120952
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- Structural and functional characterization of the Staphylococcus aureus virulence factor and vaccine candidate FhuD2
- Paolo Mariotti, Enrico Malito, Marco Biancucci, Paola Lo Surdo, Ravi P. N. Mishra, Vincenzo Nardi‑Dei, Silvana Savino, Mikkel Nissum, Glen Spraggon, Guido Grandi, Fabio Bagnoli and Matthew J. Bottomley..........683‑693
- Published as BJ Immediate Publication 31 October 2012, doi:10.1042/BJ20121426
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- The dynamic action of SecA during the initiation of protein translocation
- Vicki A. M. Gold, Sarah Whitehouse, Alice Robson and Ian Collinson..........695‑705
- Published as BJ Immediate Publication 5 November 2012, doi:10.1042/BJ20121314
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- DNA-binding regulates site-specific ubiquitination of IRF-1
- Vivien Landré, Emmanuelle Pion, Vikram Narayan, Dimitris P. Xirodimas and Kathryn L. Ball..........707‑717
- Published as BJ Immediate Publication 8 November 2012, doi:10.1042/BJ20121076
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- Functional characterization of long-chain prenyl diphosphate synthases from tomato
- Matthew O. Jones, Laura Perez‑Fons, Francesca P. Robertson, Peter M. Bramley and Paul D. Fraser..........729‑740
- Published as BJ Immediate Publication 5 November 2012, doi:10.1042/BJ20120988
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- N-Myristoylation is essential for protein phosphatases PPM1A and PPM1B to dephosphorylate their physiological substrates in cells
- Toko Chida, Masakatsu Ando, Tasuku Matsuki, Yutaro Masu, Yuko Nagaura, Teruko Takano‑Yamamoto, Shinri Tamura and Takayasu Kobayashi..........741‑749
- Published as BJ Immediate Publication 22 October 2012, doi:10.1042/BJ20121201
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- A novel transcriptional regulator, Sll1130, negatively regulates heat-responsive genes in Synechocystis sp. PCC6803
- Pilla Sankara Krishna, Balaga Radha Rani, M. Karthik Mohan, Iwane Suzuki, Sisinthy Shivaji and Jogadhenu S. S. Prakash..........751‑760
- Published as BJ Immediate Publication 22 October 2012, doi:10.1042/BJ20120928
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- Redox-dependent stability of the γ-glutamylcysteine synthetase enzyme of Escherichia coli: a novel means of redox regulation
- Shailesh Kumar, Neha Kasturia, Amit Sharma, Manish Datt and Anand K. Bachhawat..........783‑794
- Published as BJ Immediate Publication 5 November 2012, doi:10.1042/BJ20120204
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- Identification of a pathway by which glucose regulates β-catenin signalling via the cAMP/protein kinase A pathway in β-cell models
- Emmanuelle Cognard, Coralie G. Dargaville, Deborah L. Hay and Peter R. Shepherd..........803‑811
- Published as BJ Immediate Publication 3 December 2012, doi:10.1042/BJ20121454
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Abstract | Full text HTML | Full text PDF | Online Data
- Temperature-dependence of the DnaA–DNA interaction and its effect on the autoregulation of dnaA expression
- Chiara Saggioro, Anne Olliver and Bianca Sclavi..........333‑341
- Published as BJ Immediate Publication 23 October 2012, doi:10.1042/BJ20120876
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Abstract | Full text HTML | Full text PDF | Online Data
- An unusual antithrombin-binding heparin octasaccharide with an additional 3-O-sulfated glucosamine in the active pentasaccharide sequence
- Marco Guerrini, Stefano Elli, Pierre Mourier, Timothy R. Rudd, Davide Gaudesi, Benito Casu, Christian Boudier, Giangiacomo Torri and Christian Viskov..........343‑351
- Published as BJ Immediate Publication 22 October 2012, doi:10.1042/BJ20121309
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- GTPase of the immune-associated nucleotide-binding protein 5 (GIMAP5) regulates calcium influx in T-lymphocytes by promoting mitochondrial calcium accumulation
- Xi Lin Chen, Daniel Serrano, Marian Mayhue, Hans‑Joachim Wieden, Jana Stankova, Guylain Boulay, Subburaj Ilangumaran and Sheela Ramanathan..........353‑364
- Published as BJ Immediate Publication 26 October 2012, doi:10.1042/BJ20120516
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Abstract | Full text HTML | Full text PDF | Online Data | Multimedia
- The transcription factor AtDOF4.2 regulates shoot branching and seed coat formation in Arabidopsis
- Hong‑Feng Zou, Yu‑Qin Zhang, Wei Wei, Hao‑Wei Chen, Qing‑Xin Song, Yun‑Feng Liu, Ming‑Yu Zhao, Fang Wang, Bao‑Cai Zhang, Qing Lin, Wan‑Ke Zhang, Biao Ma, Yi‑Hua Zhou, Jin‑Song Zhang and Shou‑Yi Chen..........373‑388
- Published as BJ Immediate Publication 24 October 2012, doi:10.1042/BJ20110060
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- Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival
- Luke R. G. Pike, Dean C. Singleton, Francesca Buffa, Olga Abramczyk, Kanchan Phadwal, Ji‑Liang Li, Anna Katharina Simon, James T. Murray and Adrian L. Harris..........389‑400
- Published as BJ Immediate Publication 18 October 2012, doi:10.1042/BJ20120972
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- Inferring the metabolism of human orphan metabolites from their metabolic network context affirms human gluconokinase activity
- Óttar Rolfsson, Giuseppe Paglia, Manuela Magnusdóttir, Bernhard Ø. Palsson and Ines Thiele..........427‑435
- Published as BJ Immediate Publication 15 October 2012, doi:10.1042/BJ20120980
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Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner
- Lihua Jin, Christin L. Hanigan, Yu Wu, Wei Wang, Ben Ho Park, Patrick M. Woster and Robert A. Casero..........459‑468
- Published as BJ Immediate Publication 17 October 2012, doi:10.1042/BJ20121360
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- Characterization of Staphylococcus aureus EssB, an integral membrane component of the Type VII secretion system: atomic resolution crystal structure of the cytoplasmic segment
- Martin Zoltner, Paul K. Fyfe, Tracy Palmer and William N. Hunter..........469‑477
- Published as BJ Immediate Publication 25 October 2012, doi:10.1042/BJ20121209
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- AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues
- Hong Yu Wang, Serge Ducommun, Chao Quan, Bingxian Xie, Min Li, David H. Wasserman, Kei Sakamoto, Carol Mackintosh and Shuai Chen..........479‑489
- Published as BJ Immediate Publication 19 October 2012, doi:10.1042/BJ20120702
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- Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase
- Elena M. Sánchez‑Fernández, Hanna Tarhonskaya, Khalid Al‑Qahtani, Richard J. Hopkinson, James S. O. McCullagh, Christopher J. Schofield and Emily Flashman..........491‑496
- Published as BJ Immediate Publication 24 October 2012, doi:10.1042/BJ20121155
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- Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway
- Jose Félix Moruno‑Manchón, Eva Pérez‑Jiménez and Erwin Knecht..........497‑506
- Published as BJ Immediate Publication 1 November 2012, doi:10.1042/BJ20121122
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- Antibodies against the extracellular domain of human Notch1 receptor reveal the critical role of epidermal-growth-factor-like repeats 25–26in ligand binding and receptor activation
- Ankur Sharma, Annapoorni Rangarajan and Rajan R. Dighe..........519‑530
- Published as BJ Immediate Publication 17 October 2012, doi:10.1042/BJ20121153
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- Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)
- Katrina A. Hadfield, David I. Pattison, Bronwyn E. Brown, Liming Hou, Kerry‑Anne Rye, Michael J. Davies and Clare L. Hawkins..........531‑542
- Published as BJ Immediate Publication 23 October 2012, doi:10.1042/BJ20121210
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- hnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stress
- Fabrizio Damiano, Alessio Rochira, Romina Tocci, Simone Alemanno, Antonio Gnoni and Luisa Siculella..........543‑553
- Published as BJ Immediate Publication 30 October 2012, doi:10.1042/BJ20120906
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- A versatile proline/alanine transporter in the unicellular pathogen Leishmania donovani regulates amino acid homoeostasis and osmotic stress responses
- Ehud Inbar, Doreen Schlisselberg, Marianne Suter Grotemeyer, Doris Rentsch and Dan Zilberstein..........555‑566
- Published as BJ Immediate Publication 21 September 2012, doi:10.1042/BJ20121262
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- Activation of IP3 receptors requires an endogenous 1-8-14 calmodulin-binding motif
- Yi Sun, Ana M. Rossi, Taufiq Rahman and Colin W. Taylor..........39‑49
- Published as BJ Immediate Publication 26 September 2012, doi:10.1042/BJ20121034
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- Crystal structures of Cg1458 reveal a catalytic lid domain and a common catalytic mechanism for the FAH family
- Tingting Ran, Yanyan Gao, May Marsh, Wenjun Zhu, Meitian Wang, Xiang Mao, Langlai Xu, Dongqing Xu and Weiwu Wang..........51‑60
- Published as BJ Immediate Publication 10 October 2012, doi:10.1042/BJ20120913
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- Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaesthetics
- Tommy Tillman, Mary H. Cheng, Qiang Chen, Pei Tang and Yan Xu..........61‑68
- Published as BJ Immediate Publication 17 September 2012, doi:10.1042/BJ20121072
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- Ferroportin expression in haem oxygenase 1-deficient mice
- Rafał R. Starzyński, François Canonne‑Hergaux, Małgorzata Lenartowicz, Wojciech Krzeptowski, Alexandra Willemetz, Agnieszka Styś, Joanna Bierła, Piotr Pietrzak, Tomasz Dziaman and Paweł Lipiński..........69‑78
- Published as BJ Immediate Publication 20 September 2012, doi:10.1042/BJ20121139
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- Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
- Kuan Hu, Meng Zhao, Tianlong Zhang, Manwu Zha, Chen Zhong, Yu Jiang and Jianping Ding..........79‑89
- Published as BJ Immediate Publication 11 October 2012, doi:10.1042/BJ20120871
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- Design of a heterotetravalent synthetic allergen that reflects epitope heterogeneity and IgE antibody variability to study mast cell degranulation
- Michael W. Handlogten, Tanyel Kiziltepe and Basar Bilgicer..........91‑99
- Published as BJ Immediate Publication 11 October 2012, doi:10.1042/BJ20121088
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- Mind the gap: cytochrome interactions reveal electron pathways across the periplasm of Shewanella oneidensis MR-1
- Bruno M. Fonseca, Catarina M. Paquete, Sónia E. Neto, Isabel Pacheco, Cláudio M. Soares and Ricardo O. Louro..........101‑108
- Published as BJ Immediate Publication 16 October 2012, doi:10.1042/BJ20121467
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Abstract | Full text HTML | Full text PDF | Online Data | Multimedia
- Human cystathionine β-synthase (CBS) contains two classes of binding sites for S-adenosylmethionine (SAM): complex regulation of CBS activity and stability by SAM
- Angel L. Pey, Tomas Majtan, Jose M. Sanchez‑Ruiz and Jan P. Kraus..........109‑121
- Published as BJ Immediate Publication 18 September 2012, doi:10.1042/BJ20120731
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- Interdomain communication modulates the tRNA-dependent pre-transfer editing of leucyl-tRNA synthetase
- Min Tan, Bin Zhu, Ru‑Juan Liu, Xin Chen, Xiao‑Long Zhou and En‑duo Wang..........123‑131
- Published as BJ Immediate Publication 4 October 2012, doi:10.1042/BJ20121258
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Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5
- Guillermo Senisterra, Hong Wu, Abdellah Allali‑Hassani, Gregory A. Wasney, Dalia Barsyte‑Lovejoy, Ludmila Dombrovski, Aiping Dong, Kong T. Nguyen, David Smil, Yuri Bolshan, Taraneh Hajian, Hao He, Alma Seitova, Irene Chau, Fengling Li, Gennadiy Poda, Jean‑François Couture, Peter J. Brown, Rima Al‑Awar, Matthieu Schapira, Cheryl H. Arrowsmith and Masoud Vedadi..........151‑159
- Published as BJ Immediate Publication 19 September 2012, doi:10.1042/BJ20121280
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- Rezymogenation of active urokinase induced by an inhibitory antibody
- Longguang Jiang, Kenneth A. Botkjaer, Lisbeth M. Andersen, Cai Yuan, Peter A. Andreasen and Mingdong Huang..........161‑166
- Published as BJ Immediate Publication 27 September 2012, doi:10.1042/BJ20121132
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- Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum
- Shaun B. Reeksting, Ingrid B. Müller, Pieter B. Burger, Emmanuel S. Burgos, Laurent Salmon, Abraham I. Louw, Lyn‑Marie Birkholtz and Carsten Wrenger..........175‑187
- Published as BJ Immediate Publication 8 October 2012, doi:10.1042/BJ20120925
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- Haem oxygenase-1 overexpression alters intracellular iron distribution
- Lilibeth Lanceta, Chi Li, Augustine M. Choi and John W. Eaton..........189‑194
- Published as BJ Immediate Publication 19 September 2012, doi:10.1042/BJ20120936
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Abstract | Full text HTML | Full text PDF | Online Data
- Pex5p stabilizes Pex14p: a study using a newly isolated pex5 CHO cell mutant, ZPEG101
- Ryuichi Natsuyama, Kanji Okumoto and Yukio Fujiki..........195‑207
- Published as BJ Immediate Publication 26 September 2012, doi:10.1042/BJ20120911
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- Formation of high-molecular-weight angiotensinogen during pregnancy is a result of competing redox reactions with the proform of eosinophil major basic protein
- Søren Kløverpris, Louise L. Skov, Simon Glerup, Kasper Pihl, Michael Christiansen and Claus Oxvig..........209‑217
- Published as BJ Immediate Publication 4 October 2012, doi:10.1042/BJ20120801
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- Dynamic changes in genomic histone association and modification during activation of the ASNS and ATF3 genes by amino acid limitation
- Mukundh N. Balasubramanian, Jixiu Shan and Michael S. Kilberg..........219‑229
- Published as BJ Immediate Publication 17 September 2012, doi:10.1042/BJ20120958
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- Ribavirin-induced intracellular GTP depletion activates transcription elongation in coagulation Factor VII gene expression
- Atsuo Suzuki, Yuhri Miyawaki, Eriko Okuyama, Moe Murata, Yumi Ando, Io Kato, Yuki Takagi, Akira Takagi, Takashi Murate, Hidehiko Saito and Tetsuhito Kojima..........231‑239
- Published as BJ Immediate Publication 11 October 2012, doi:10.1042/BJ20121286
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- TfR1 interacts with the IKK complex and is involved in IKK–NF-κB signalling
- Niall S. Kenneth, Sharon Mudie, Sanne Naron and Sonia Rocha..........275‑284
- Published as BJ Immediate Publication 27 September 2012, doi:10.1042/BJ20120625
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- Chitin-binding proteins of Artemia diapause cysts participate in formation of the embryonic cuticle layer of cyst shells
- Wen‑Ming Ma, Hua‑Wei Li, Zhong‑Min Dai, Jin‑Shu Yang, Fan Yang and Wei‑Jun Yang..........285‑294
- Published as BJ Immediate Publication 26 September 2012, doi:10.1042/BJ20121259
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CFTR mutations altering CFTR fragmentation
- Kendra Tosoni, Michelle Stobbart, Diane M. Cassidy, Andrea Venerando, Mario A. Pagano, Simão Luz, Margarida D. Amaral, Karl Kunzelmann, Lorenzo A. Pinna, Carlos M. Farinha and Anil Mehta..........295‑305
- Published as BJ Immediate Publication 15 October 2012, doi:10.1042/BJ20121240
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Volume 448
- Structural and functional insights into the role of the N-terminal Mps1 TPR domain in the SAC (spindle assembly checkpoint)
- Philippe Thebault, Dimitri Y. Chirgadze, Zhen Dou, Tom L. Blundell, Sabine Elowe and Victor M. Bolanos‑Garcia..........321‑328
- Published as BJ Immediate Publication 16 October 2012, doi:10.1042/BJ20121448
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Erlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domain
- Jin H. Park, Yingting Liu, Mark A. Lemmon and Ravi Radhakrishnan..........417‑423
- Published as BJ Immediate Publication 29 October 2012, doi:10.1042/BJ20121513
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- Defective valyl-tRNA synthetase hampers the mitochondrial respiratory chain in Neurospora crassa
- Margarida Duarte and Arnaldo Videira..........297‑306
- Published as BJ Immediate Publication 7 September 2012, doi:10.1042/BJ20120963
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- The activation loop of PKA catalytic isoforms is differentially phosphorylated by Pkh protein kinases in Saccharomyces cerevisiae
- Steven Haesendonckx, Vanesa Tudisca, Karin Voordeckers, Silvia Moreno, Johan M. Thevelein and Paula Portela..........307‑320
- Published as BJ Immediate Publication 7 September 2012, doi:10.1042/BJ20121061
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- MpaA is a murein-tripeptide-specific zinc carboxypeptidase that functions as part of a catabolic pathway for peptidoglycan-derived peptides in γ-proteobacteria
- Abbas Maqbool, Mireille Hervé, Dominique Mengin‑Lecreulx, Anthony J. Wilkinson and Gavin H. Thomas..........329‑341
- Published as BJ Immediate Publication 12 September 2012, doi:10.1042/BJ20121164
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- The small heat-shock protein αB-crystallin uses different mechanisms of chaperone action to prevent the amorphous versus fibrillar aggregation of α-lactalbumin
- Melissa Kulig and Heath Ecroyd..........343‑352
- Published as BJ Immediate Publication 24 September 2012, doi:10.1042/BJ20121187
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- Controlled nuclear import of the transcription factor NTL6 reveals a cytoplasmic role of SnRK2.8 in the drought-stress response
- Mi Jung Kim, Mi‑Jeong Park, Pil Joon Seo, Jin‑Su Song, Hie‑Joon Kim and Chung‑Mo Park..........353‑363
- Published as BJ Immediate Publication 11 September 2012, doi:10.1042/BJ20120244
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- Glucan affinity of starch synthase IIa determines binding of starch synthase I and starch-branching enzyme IIb to starch granules
- Fushan Liu, Nadya Romanova, Elizabeth A. Lee, Regina Ahmed, Martin Evans, Elliot P. Gilbert, Matthew K. Morell, Michael J. Emes and Ian J. Tetlow..........373‑387
- Published as BJ Immediate Publication 10 September 2012, doi:10.1042/BJ20120573
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- The substrate/product-binding modes of a novel GH120 β-xylosidase (XylC) from Thermoanaerobacterium saccharolyticum JW/SL-YS485
- Chun‑Hsiang Huang, Yu Sun, Tzu‑Ping Ko, Chun‑Chi Chen, Yingying Zheng, Hsiu‑Chien Chan, Xuefei Pang, Juergen Wiegel, Weilan Shao and Rey‑Ting Guo..........401‑407
- Published as BJ Immediate Publication 20 September 2012, doi:10.1042/BJ20121359
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Mislocalization and inhibition of acetyl-CoA carboxylase 1 by a synthetic small molecule
- Dongju Jung, Lutfi Abu‑Elheiga, Rie Ayuzawa, Ziwei Gu, Takashi Shirakawa, Yukio Fujiki, Norio Nakatsuji, Salih J. Wakil and Motonari Uesugi..........409‑416
- Published as BJ Immediate Publication 15 October 2012, doi:10.1042/BJ20121158
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- Persulfide formation on mitochondrial cysteine desulfurase: enzyme activation by a eukaryote-specific interacting protein and Fe–S cluster synthesis
- Alok Pandey, Ramesh Golla, Heeyong Yoon, Andrew Dancis and Debkumar Pain..........171‑187
- Published as BJ Immediate Publication 28 August 2012, doi:10.1042/BJ20120951
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2-APB-potentiated channels amplify CatSper-induced Ca2+ signals in human sperm
- Linda Lefièvre, Katherine Nash, Steven Mansell, Sarah Costello, Emma Punt, Joao Correia, Jennifer Morris, Jackson Kirkman‑Brown, Stuart M. Wilson, Christopher L. R. Barratt and Stephen Publicover..........189‑200
- Published as BJ Immediate Publication 3 September 2012, doi:10.1042/BJ20120339
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- Structural insight into how Pseudomonas aeruginosa peptidoglycan-hydrolase Tse1 and its immunity protein Tsi1 function
- Guijun Shang, Xiuhua Liu, Defen Lu, Junbing Zhang, Ning Li, Chunyuan Zhu, Shiheng Liu, Qian Yu, Yanyu Zhao, Heqiao Zhang, Junqiang Hu, Huaixing Cang, Sujuan Xu and Lichuan Gu..........201‑211
- Published as BJ Immediate Publication 29 August 2012, doi:10.1042/BJ20120668
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- The proximal C-terminus of α1C subunits is necessary for junctional membrane targeting of cardiac L-type calcium channels
- Tsutomu Nakada, Bernhard E. Flucher, Toshihide Kashihara, Xiaona Sheng, Toshihide Shibazaki, Miwa Horiuchi‑Hirose, Simmon Gomi, Masamichi Hirose and Mitsuhiko Yamada..........221‑231
- Published as BJ Immediate Publication 28 August 2012, doi:10.1042/BJ20120773
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- Nocturnin in the demosponge Suberites domuncula: a potential circadian clock protein controlling glycogenin synthesis in sponges
- Werner E. G. Müller, Xiaohong Wang, Vlad A. Grebenjuk, Michael Korzhev, Matthias Wiens, Ute Schlossmacher and Heinz C. Schröder..........233‑242
- Published as BJ Immediate Publication 28 August 2012, doi:10.1042/BJ20120357
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- Regulation of the V-type ATPase by redox modulation
- Thorsten Seidel, Stefan Scholl, Melanie Krebs, Florian Rienmüller, Irene Marten, Rainer Hedrich, Miriam Hanitzsch, Patricia Janetzki, Karl‑Josef Dietz and Karin Schumacher..........243‑251
- Published as BJ Immediate Publication 4 September 2012, doi:10.1042/BJ20120976
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- Probing why trypanosomes assemble atypical cytochrome c with an AxxCH haem-binding motif instead of CxxCH
- Michael L. Ginger, Katharine A. Sam and James W. A. Allen..........253‑260
- Published as BJ Immediate Publication 28 August 2012, doi:10.1042/BJ20120757
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- Identification and characterization of a kunzeaol synthase from Thapsia garganica: implications for the biosynthesis of the pharmaceutical thapsigargin
- Benjamin Pickel, Damian P. Drew, Tom Manczak, Corinna Weitzel, Henrik T. Simonsen and Dae‑Kyun Ro..........261‑271
- Published as BJ Immediate Publication 31 August 2012, doi:10.1042/BJ20120654
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- Activation of PLC by an endogenous cytokine (GBP) in Drosophila S3 cells and its application as a model for studying inositol phosphate signalling through ITPK1
- Yixing Zhou, Shilan Wu, Huanchen Wang, Yoichi Hayakawa, Gary S. Bird and Stephen B. Shears..........273‑283
- Published as BJ Immediate Publication 29 August 2012, doi:10.1042/BJ20120730
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- Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors
- Ayaz Najafov, Natalia Shpiro and Dario R. Alessi..........285‑295
- Published as BJ Immediate Publication 3 October 2012, doi:10.1042/BJ20121287
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- Multiple isoforms of the translation initiation factor eIF4GII are generated via use of alternative promoters, splice sites and a non-canonical initiation codon
- Mark J. Coldwell, Ulrike Sack, Joanne L. Cowan, Rachel M. Barrett, Markete Vlasak, Keiley Sivakumaran and Simon J. Morley..........1‑11
- Published as BJ Immediate Publication 21 August 2012, doi:10.1042/BJ20111765
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- DNA-dependent Oct4–Sox2 interaction and diffusion properties characteristic of the pluripotent cell state revealed by fluorescence spectroscopy
- Chen Sok Lam, Tapan Kumar Mistri, Yong Hwee Foo, Thankiah Sudhaharan, Hui Theng Gan, David Rodda, Leng Hiong Lim, Chai Chou, Paul Robson, Thorsten Wohland and Sohail Ahmed..........21‑33
- Published as BJ Immediate Publication 22 August 2012, doi:10.1042/BJ20120725
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- Scar/WAVE3 contributes to motility and plasticity of lamellipodial dynamics but not invasion in three dimensions
- Heather J. Spence, Paul Timpson, Hao Ran Tang, Robert H. Insall and Laura M. Machesky..........35‑42
- Published as BJ Immediate Publication 21 August 2012, doi:10.1042/BJ20112206
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- CD36 inhibition prevents lipid accumulation and contractile dysfunction in rat cardiomyocytes
- Yeliz Angin, Laura K. M. Steinbusch, Peter J. Simons, Sabrina Greulich, Nicole T. H. Hoebers, Kim Douma, Marc A. M. J. van Zandvoort, Will A. Coumans, Wino Wijnen, Michaela Diamant, D. Margriet Ouwens, Jan F. C. Glatz and Joost J. F. P. Luiken..........43‑53
- Published as BJ Immediate Publication 10 July 2012, doi:10.1042/BJ20120060
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- Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporation
- Jonas Boehringer, Christiane Riedinger, Konstantinos Paraskevopoulos, Eachan O. D. Johnson, Edward D. Lowe, Christina Khoudian, Dominique Smith, Martin E. M. Noble, Colin Gordon and Jane A. Endicott..........55‑65
- Published as BJ Immediate Publication 20 August 2012, doi:10.1042/BJ20120542
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- A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase
- Hugh P. Morgan, Martin J. Walsh, Elizabeth A. Blackburn, Martin A. Wear, Matthew B. Boxer, Min Shen, Henrike Veith, Iain W. McNae, Matthew W. Nowicki, Paul A. M. Michels, Douglas S. Auld, Linda A. Fothergill‑Gilmore and Malcolm D. Walkinshaw..........67‑72
- Published as BJ Immediate Publication 20 August 2012, doi:10.1042/BJ20121014
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- Targeted oxidation of Torpedo californica acetylcholinesterase by singlet oxygen: identification of N-formylkynurenine tryptophan derivatives within the active-site gorge of its complex with the photosensitizer Methylene Blue
- Mathilde M. Triquigneaux, Marilyn Ehrenshaft, Esther Roth, Israel Silman, Yakov Ashani, Ronald P. Mason, Lev Weiner and Leesa J. Deterding..........83‑91
- Published as BJ Immediate Publication 13 August 2012, doi:10.1042/BJ20120992
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- Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels
- Nicole Zimmermann, Jürgen Zschocke, Tatjana Perisic, Shuang Yu, Florian Holsboer and Theo Rein..........93‑102
- Published as BJ Immediate Publication 13 August 2012, doi:10.1042/BJ20120674
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- A non-B DNA can replace heptamer of V(D)J recombination when present along with a nonamer: implications in chromosomal translocations and cancer
- Mayilaadumveettil Nishana and Sathees C. Raghavan..........115‑125
- Published as BJ Immediate Publication 15 August 2012, doi:10.1042/BJ20121031
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- BIK (NBK) is a mediator of the sensitivity of Fanconi anaemia group C lymphoblastoid cell lines to interstrand DNA cross-linking agents
- Inés Prieto‑Remón, Dámaso Sánchez‑Carrera, Mónica López‑Duarte, Carlos Richard and Carlos Pipaón..........153‑163
- Published as BJ Immediate Publication 8 August 2012, doi:10.1042/BJ20120327
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Volume 447
- Coupling of ryanodine receptor 2 and voltage-dependent anion channel 2 is essential for Ca2+ transfer from the sarcoplasmic reticulum to the mitochondria in the heart
- Choon Kee Min, Dong Rim Yeom, Kyung‑Eun Lee, Hye‑Kyeong Kwon, Moonkyung Kang, Yeon‑Soo Kim, Zee Yong Park, Hyesung Jeon and Do Han Kim..........371‑379
- Published as BJ Immediate Publication 7 August 2012, doi:10.1042/BJ20120705
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- Functional comparison of Deinococcus radiodurans Dps proteins suggests distinct in vivo roles
- Brian J. Reon, Khoa H. Nguyen, Gargi Bhattacharyya and Anne Grove..........381‑391
- Published as BJ Immediate Publication 2 August 2012, doi:10.1042/BJ20120902
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Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas Gβγ subunits exert opposing effects depending on the G-protein source
- Jia X. Shen, Sebastian Wachten, Michelle L. Halls, Katy L. Everett and Dermot M. F. Cooper..........393‑405
- Published as BJ Immediate Publication 20 August 2012, doi:10.1042/BJ20120279
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- Promoter-associated small double-stranded RNA interacts with heterogeneous nuclear ribonucleoprotein A2/B1 to induce transcriptional activation
- Jia Hu, Zhong Chen, Ding Xia, Jia Wu, Hua Xu and Zhang‑Qun Ye..........407‑416
- Published as BJ Immediate Publication 5 October 2012, doi:10.1042/BJ20120256
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- HER3 signalling is regulated through a multitude of redundant mechanisms in HER2-driven tumour cells
- Dhara N. Amin, Natalia Sergina, Lionel Lim, Andrei Goga and Mark M. Moasser..........417‑425
- Published as BJ Immediate Publication 2 August 2012, doi:10.1042/BJ20120724
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- Characterization of ML-IAP protein stability and physiological role in vivo
- Eugene Varfolomeev, Elham Moradi, Jasmin N. Dynek, Jiping Zha, Anna V. Fedorova, Kurt Deshayes, Wayne J. Fairbrother, Kim Newton, Jennifer Le Couter and Domagoj Vucic..........427‑436
- Published as BJ Immediate Publication 2 August 2012, doi:10.1042/BJ20121103
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- Regulation of hepatic insulin sensitivity by activating signal co-integrator-2
- Geun Hyang Kim, Kyung Jin Lee, Gyun‑Sik Oh, Jin Yoon, Hae Won Kim and Seung‑Whan Kim..........437‑447
- Published as BJ Immediate Publication 6 August 2012, doi:10.1042/BJ20120861
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- Multiple microRNAs induced by Cdx1 suppress Cdx2 in human colorectal tumour cells
- Takanobu Tagawa, Takeshi Haraguchi, Hiroaki Hiramatsu, Kazuyoshi Kobayashi, Kouhei Sakurai, Ken‑Ichi Inada and Hideo Iba..........449‑455
- Published as BJ Immediate Publication 31 July 2012, doi:10.1042/BJ20120434
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- Protein kinase Cϵ activity induces anti-inflammatory and anti-apoptotic genes via an ERK1/2- and NF-κB-dependent pathway to enhance vascular protection
- Odile Dumont, Hayley Mylroie, Andrea Bauer, Damien Calay, Andrea Sperone, Clare Thornton, Shahir S. Hamdulay, Nadira Ali, Joseph J. Boyle, Joan R. Choo, Allen M. Samarel, Dorian O. Haskard, Anna M. Randi, Paul C. Evans and Justin C. Mason..........193‑204
- Published as BJ Immediate Publication 31 July 2012, doi:10.1042/BJ20120574
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- Molecular structure of human GM-CSF in complex with a disease-associated anti-human GM-CSF autoantibody and its potential biological implications
- Michaela Blech, Daniel Seeliger, Barbara Kistler, Margit M. T. Bauer, Mathias Hafner, Stefan Hörer, Markus Zeeb, Herbert Nar and John E. Park..........205‑215
- Published as BJ Immediate Publication 27 July 2012, doi:10.1042/BJ20120884
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- Mapping the N-glycome of human von Willebrand factor
- Kevin Canis, Thomas A. J. McKinnon, Agata Nowak, Stuart M. Haslam, Maria Panico, Howard R. Morris, Mike A. Laffan and Anne Dell..........217‑228
- Published as BJ Immediate Publication 31 July 2012, doi:10.1042/BJ20120810
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Dedifferentiated follicular granulosa cells derived from pig ovary can transdifferentiate into osteoblasts
- Yoshinao Oki, Hiromasa Ono, Takeharu Motohashi, Nobuki Sugiura, Hiroyuki Nobusue and Koichiro Kano..........239‑248
- Published as BJ Immediate Publication 27 July 2012, doi:10.1042/BJ20120172
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- Nitric oxide inhibits the ATPase activity of the chaperone-like AAA+ ATPase CDC48, a target for S-nitrosylation in cryptogein signalling in tobacco cells
- Jéremy Astier, Angélique Besson‑Bard, Olivier Lamotte, Jean Bertoldo, Stéphane Bourque, Hernán Terenzi and David Wendehenne..........249‑260
- Published as BJ Immediate Publication 27 July 2012, doi:10.1042/BJ20120257
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- DJ-1 promotes the proteasomal degradation of Fis1: implications of DJ-1 in neuronal protection
- Qiang Zhang, Junbing Wu, Rong Wu, Jun Ma, Guiping Du, Renjie Jiao, Yong Tian, Zheng Zheng and Zengqiang Yuan..........261‑269
- Published as BJ Immediate Publication 8 August 2012, doi:10.1042/BJ20120598
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- In vitro reconstitution of RNA primer removal in Archaea reveals the existence of two pathways
- Ghislaine Henneke..........271‑280
- Published as BJ Immediate Publication 31 July 2012, doi:10.1042/BJ20120959
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Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components
- Masato Ogura, Junko Yamaki, Miwako K. Homma and Yoshimi Homma..........281‑289
- Published as BJ Immediate Publication 24 July 2012, doi:10.1042/BJ20120509
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- Characterization of Arabidopsis calcium-dependent protein kinases: activated or not by calcium?
- Marie Boudsocq, Marie‑Jo Droillard, Leslie Regad and Christiane Laurière..........291‑299
- Published as BJ Immediate Publication 24 July 2012, doi:10.1042/BJ20112072
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- Digoxin and ouabain induce the efflux of cholesterol via liver X receptor signalling and the synthesis of ATP in cardiomyocytes
- Ivana Campia, Valentina Sala, Joanna Kopecka, Christian Leo, Nico Mitro, Costanzo Costamagna, Donatella Caruso, Gianpiero Pescarmona, Tiziana Crepaldi, Dario Ghigo, Amalia Bosia and Chiara Riganti..........301‑311
- Published as BJ Immediate Publication 30 July 2012, doi:10.1042/BJ20120200
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- Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells
- Shin‑Ae Kang, Hyun‑Soo Cho, Jong Bok Yoon, In Kwon Chung and Seung‑Taek Lee..........313‑320
- Published as BJ Immediate Publication 31 July 2012, doi:10.1042/BJ20120803
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- Selective activation of Toll-like receptor 7 in activated hepatic stellate cells may modulate their profibrogenic phenotype
- Ming‑Huei Chou, Ying‑Hsien Huang, Tsun‑Mei Lin, Yung‑Ying Du, Po‑Chin Tsai, Chih‑Sung Hsieh and Jiin‑Haur Chuang..........25‑34
- Published as BJ Immediate Publication 5 July 2012, doi:10.1042/BJ20112058
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- Structural origin of polymorphism of Alzheimer's amyloid β-fibrils
- Audrey Agopian and Zhefeng Guo..........43‑50
- Published as BJ Immediate Publication 23 July 2012, doi:10.1042/BJ20120034
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- Cholesterol accumulation inhibits ER to Golgi transport and protein secretion: studies of apolipoprotein E and VSVGt
- Maaike Kockx, Donna L. Dinnes, Kuan‑Yen Huang, Laura J. Sharpe, Wendy Jessup, Andrew J. Brown and Leonard Kritharides..........51‑60
- Published as BJ Immediate Publication 2 July 2012, doi:10.1042/BJ20111891
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- From prediction to experimental validation: desmoglein 2 is a functionally relevant substrate of matriptase in epithelial cells and their reciprocal relationship is important for cell adhesion
- Vinita Wadhawan, Yogesh A. Kolhe, Nikhil Sangith, Amit Kumar Singh Gautam and Prasanna Venkatraman..........61‑70
- Published as BJ Immediate Publication 11 July 2012, doi:10.1042/BJ20111432
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- Regulation of S100A2 expression by TGF-β-induced MEK/ERK signalling and its role in cell migration/invasion
- Sarwat Naz, Prathibha Ranganathan, Priyanka Bodapati, Arun H. Shastry, Laxmi N. Mishra and Paturu Kondaiah..........81‑91
- Published as BJ Immediate Publication 2 July 2012, doi:10.1042/BJ20120014
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- Phospho-regulation of KIBRA by CDK1 and CDC14 phosphatase controls cell-cycle progression
- Ming Ji, Shuping Yang, Yuanhong Chen, Ling Xiao, Lin Zhang and Jixin Dong..........93‑102
- Published as BJ Immediate Publication 11 July 2012, doi:10.1042/BJ20120751
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- A novel pathway of ceramide metabolism in Saccharomyces cerevisiae
- Natalia S. Voynova, Christine Vionnet, Christer S. Ejsing and Andreas Conzelmann..........103‑114
- Published as BJ Immediate Publication 28 June 2012, doi:10.1042/BJ20120712
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- PDIp is a major intracellular oestrogen-storage protein that modulates tissue levels of oestrogen in the pancreas
- Xinmiao Fu, Pan Wang, Masayuki Fukui, Cheng Long, Linxiang Yin, Hye Joung Choi and Bao Ting Zhu..........115‑123
- Published as BJ Immediate Publication 2 July 2012, doi:10.1042/BJ20120868
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Selective STAT3-α or -β expression reveals spliceform-specific phosphorylation kinetics, nuclear retention and distinct gene expression outcomes
- Ivan H. W. Ng, Dominic C. H. Ng, David A. Jans and Marie A. Bogoyevitch..........125‑136
- Published as BJ Immediate Publication 17 July 2012, doi:10.1042/BJ20120941
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- A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle
- Yu‑Chiang Lai, Yang Liu, Roxane Jacobs and Mark H. Rider..........137‑147
- Published as BJ Immediate Publication 13 July 2012, doi:10.1042/BJ20120772
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- RSK phosphorylates SOS1 creating 14-3-3-docking sites and negatively regulating MAPK activation
- Madhurima Saha, Audrey Carriere, Mujeeburahiman Cheerathodi, Xiaocui Zhang, Geneviève Lavoie, John Rush, Philippe P. Roux and Bryan A. Ballif..........159‑166
- Published as BJ Immediate Publication 25 July 2012, doi:10.1042/BJ20120938
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- Thiophosphate and selenite conversely modulate cell death induced by glutathione depletion or cisplatin: effects related to activity and Sec contents of thioredoxin reductase
- Xiaoxiao Peng, Jianqiang Xu and Elias S. J. Arnér..........167‑174
- Published as BJ Immediate Publication 11 July 2012, doi:10.1042/BJ20120683
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Volume 446
- The biological roles of glutaredoxins
- Elke Ströher and A. Harvey Millar..........333‑348
- Published on the Internet 28 August 2012, doi:10.1042/BJ20112131
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- In vivo phosphorylation of FtsZ2 in Arabidopsis thaliana
- Daniela Gargano, Jodi Maple‑Grødem and Simon G. Møller..........517‑521
- Published as BJ Immediate Publication 24 July 2012, doi:10.1042/BJ20120404
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- Foxk1 recruits the Sds3 complex and represses gene expression in myogenic progenitors
- Xiaozhong Shi, David C. Seldin and Daniel J. Garry..........349‑357
- Published as BJ Immediate Publication 20 June 2012, doi:10.1042/BJ20120563
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- Quantitative proteomic analysis of induced pluripotent stem cells derived from a human Huntington's disease patient
- Jung‑Il Chae, Dong‑Wook Kim, Nayeon Lee, Young‑Joo Jeon, Iksoo Jeon, Jihye Kwon, Jumi Kim, Yunjo Soh, Dong‑Seok Lee, Kang Seok Seo, Nag‑Jin Choi, Byoung Chul Park, Sung Hyun Kang, Joohyun Ryu, Seung‑Hun Oh, Dong Ah Shin, Dong Ryul Lee, Jeong Tae Do, In‑Hyun Park, George Q. Daley and Jihwan Song..........359‑371
- Published as BJ Immediate Publication 13 June 2012, doi:10.1042/BJ20111495
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Human cells enter mitosis with damaged DNA after treatment with pharmacological concentrations of genotoxic agents
- Philip M. Kubara, Sophie Kernéis‑Golsteyn, Aurélie Studény, Brittany B. Lanser, Laurent Meijer and Roy M. Golsteyn..........373‑381
- Published as BJ Immediate Publication 11 June 2012, doi:10.1042/BJ20120385
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Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells
- Kyubo Kim, Youlia M. Petrova, Brenton L. Scott, Rupesh Nigam, Anurag Agrawal, Christopher M. Evans, Zoulikha Azzegagh, Alejandra Gomez, Elsa M. Rodarte, Vesa M. Olkkonen, Rustam Bagirzadeh, Lucia Piccotti, Binhui Ren, Joo‑Heon Yoon, James A. McNew, Roberto Adachi, Michael J. Tuvim and Burton F. Dickey..........383‑394
- Published as BJ Immediate Publication 14 June 2012, doi:10.1042/BJ20120057
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Crystal structure of the dopamine N-acetyltransferase–acetyl-CoA complex provides insights into the catalytic mechanism
- Kuo‑Chang Cheng, Jhen‑Ni Liao and Ping‑Chiang Lyu..........395‑404
- Published as BJ Immediate Publication 21 June 2012, doi:10.1042/BJ20120520
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- An aminoquinazoline inhibitor of the essential bacterial cell wall synthetic enzyme GlmU has a unique non-protein-kinase-like binding mode
- Nicholas A. Larsen, Tory J. Nash, Marshall Morningstar, Adam B. Shapiro, Camil Joubran, Carolyn J. Blackett, Arthur D. Patten, P. Ann Boriack‑Sjodin and Peter Doig..........405‑413
- Published as BJ Immediate Publication 22 June 2012, doi:10.1042/BJ20120596
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- Endoplasmic reticulum factor ERLIN2 regulates cytosolic lipid content in cancer cells
- Guohui Wang, Xuebao Zhang, Jin‑Sook Lee, Xiaogang Wang, Zeng‑Quan Yang and Kezhong Zhang..........415‑425
- Published as BJ Immediate Publication 13 June 2012, doi:10.1042/BJ20112050
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- Characterization of cytoskeletal protein 4.1R interaction with NHE1 (Na+/H+ exchanger isoform 1)
- Wataru Nunomura, Sheryl P. Denker, Diane L. Barber, Yuichi Takakuwa and Philippe Gascard..........427‑435
- Published as BJ Immediate Publication 25 June 2012, doi:10.1042/BJ20120535
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- The G-protein regulator LGN modulates the activity of the NO receptor soluble guanylate cyclase
- Swati Chauhan, Filip Jelen, Iraida Sharina and Emil Martin..........445‑453
- Published as BJ Immediate Publication 13 June 2012, doi:10.1042/BJ20111882
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- Novel atypical PKC inhibitors prevent vascular endothelial growth factor-induced blood–retinal barrier dysfunction
- Paul M. Titchenell, Cheng‑Mao Lin, Jason M. Keil, Jeffrey M. Sundstrom, Charles D. Smith and David A. Antonetti..........455‑467
- Published as BJ Immediate Publication 22 June 2012, doi:10.1042/BJ20111961
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- Dimerization is necessary for MIM-mediated membrane deformation and endocytosis
- Meng Cao, Tailan Zhan, Min Ji and Xi Zhan..........469‑475
- Published as BJ Immediate Publication 22 June 2012, doi:10.1042/BJ20120329
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- Low temperature highlights the functional role of the cell wall integrity pathway in the regulation of growth in Saccharomyces cerevisiae
- Isaac Córcoles‑Sáez, Lídia Ballester‑Tomas, Maria A. de la Torre‑Ruiz, Jose A. Prieto and Francisca Randez‑Gil..........477‑488
- Published as BJ Immediate Publication 29 June 2012, doi:10.1042/BJ20120634
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- Effect of homomeric P450–P450 complexes on P450 function
- James R. Reed, J. Patrick Connick, Dongmei Cheng, George F. Cawley and Wayne L. Backes..........489‑497
- Published as BJ Immediate Publication 28 June 2012, doi:10.1042/BJ20120636
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- Erythrocyte storage increases rates of NO and nitrite scavenging: implications for transfusion-related toxicity
- Ryan Stapley, Benjamin Y. Owusu, Angela Brandon, Marianne Cusick, Cilina Rodriguez, Marisa B. Marques, Jeffrey D. Kerby, Scott R. Barnum, Jordan A. Weinberg, Jack R. Lancaster and Rakesh P. Patel..........499‑508
- Published as BJ Immediate Publication 21 June 2012, doi:10.1042/BJ20120675
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- USP18 establishes the transcriptional and anti-proliferative interferon α/β differential
- Véronique Francois‑Newton, Mark Livingstone, Béatrice Payelle‑Brogard, Gilles Uzé and Sandra Pellegrini..........509‑516
- Published as BJ Immediate Publication 26 June 2012, doi:10.1042/BJ20120541
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- Malaria parasite type 4 equilibrative nucleoside transporters (ENT4) are purine transporters with distinct substrate specificity
- I. J. Frame, Emilio F. Merino, Vern L. Schramm, María B. Cassera and Myles H. Akabas..........179‑190
- Published as BJ Immediate Publication 6 June 2012, doi:10.1042/BJ20112220
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- A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products
- James R. Krycer, Lisa Phan and Andrew J. Brown..........191‑201
- Published as BJ Immediate Publication 1 June 2012, doi:10.1042/BJ20120545
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- Transcriptional networks driving enhancer function in the CFTR gene
- Jenny L. Kerschner and Ann Harris..........203‑212
- Published as BJ Immediate Publication 6 June 2012, doi:10.1042/BJ20120693
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- MMP proteolysis of the human extracellular matrix protein aggrecan is mainly a process of normal turnover
- André Struglics and Maria Hansson..........213‑223
- Published as BJ Immediate Publication 6 June 2012, doi:10.1042/BJ20120274
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- Acidic stress induces the formation of P-bodies, but not stress granules, with mild attenuation of bulk translation in Saccharomyces cerevisiae
- Aya Iwaki and Shingo Izawa..........225‑233
- Published as BJ Immediate Publication 12 June 2012, doi:10.1042/BJ20120583
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- Structural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphism
- Ivana Biljan, Gabriele Giachin, Gregor Ilc, Igor Zhukov, Janez Plavec and Giuseppe Legname..........243‑251
- Published as BJ Immediate Publication 8 June 2012, doi:10.1042/BJ20111940
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- Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster
- Qian Han, Howard Robinson and Jianyong Li..........253‑260
- Published as BJ Immediate Publication 12 June 2012, doi:10.1042/BJ20120416
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- The C-terminal rod 2 fragment of filamin A forms a compact structure that can be extended
- Salla Ruskamo, Robert Gilbert, Gregor Hofmann, Pengju Jiang, Iain D. Campbell, Jari Ylänne and Ulla Pentikäinen..........261‑269
- Published as BJ Immediate Publication 8 June 2012, doi:10.1042/BJ20120361
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- Determination of primary sequence specificity of Arabidopsis MAPKs MPK3 and MPK6 leads to identification of new substrates
- Carolin Sörensson, Marit Lenman, Jenny Veide‑Vilg, Simone Schopper, Thomas Ljungdahl, Morten Grøtli, Markus J. Tamás, Scott C. Peck and Erik Andreasson..........271‑278
- Published as BJ Immediate Publication 25 May 2012, doi:10.1042/BJ20111809
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- Systematic interaction analysis of human lipocalin-type prostaglandin D synthase with small lipophilic ligands
- Satoshi Kume, Young‑Ho Lee, Yuya Miyamoto, Harumi Fukada, Yuji Goto and Takashi Inui..........279‑289
- Published as BJ Immediate Publication 8 June 2012, doi:10.1042/BJ20120324
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- Interaction specificity between the chaperone and proteolytic components of the cyanobacterial Clp protease
- Anders Tryggvesson, Frida M. Ståhlberg, Axel Mogk, Kornelius Zeth and Adrian K. Clarke..........311‑320
- Published as BJ Immediate Publication 1 June 2012, doi:10.1042/BJ20120649
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- Homodimerization and isoform-specific heterodimerization of neuroligins
- Alexandros Poulopoulos, Tolga Soykan, Liam P. Tuffy, Matthieu Hammer, Frédérique Varoqueaux and Nils Brose..........321‑330
- Published as BJ Immediate Publication 6 June 2012, doi:10.1042/BJ20120808
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- A novel role for the transcription factor HIF-1α in the formation of mast cell extracellular traps
- Katja Branitzki‑Heinemann, Cheryl Y. Okumura, Lena Völlger, Yuko Kawakami, Toshiaki Kawakami, Hassan Y. Naim, Victor Nizet and Maren Von Köckritz‑Blickwede..........159‑163
- Published as BJ Immediate Publication 28 June 2012, doi:10.1042/BJ20120658
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- A functional interaction between the MAGUK protein hDlg and the gap junction protein connexin 43 in cervical tumour cells
- Alasdair I. MacDonald, Peng Sun, Hegel Hernandez‑Lopez, Trond Aasen, Malcolm B. Hodgins, Michael Edward, Sally Roberts, Paola Massimi, Miranda Thomas, Lawrence Banks and Sheila V. Graham..........9‑21
- Published as BJ Immediate Publication 1 June 2012, doi:10.1042/BJ20111144
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Myostatin is a novel tumoral factor that induces cancer cachexia
- Sudarsanareddy Lokireddy, Isuru Wijerupage Wijesoma, Sabeera Bonala, Meng Wei, Siu Kwan Sze, Craig McFarlane, Ravi Kambadur and Mridula Sharma..........23‑36
- Published as BJ Immediate Publication 23 May 2012, doi:10.1042/BJ20112024
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- The variable N-terminal region of DDX5 contains structural elements and auto-inhibits its interaction with NS5B of hepatitis C virus
- Sujit Dutta, Garvita Gupta, Yook‑Wah Choi, Masayo Kotaka, Burtram C. Fielding, Jianxing Song and Yee‑Joo Tan..........37‑46
- Published as BJ Immediate Publication 28 May 2012, doi:10.1042/BJ20120001
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- Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice
- Ozlem Guzeloglu‑Kayisli, Maria D. Lalioti, Fulya Aydiner, Isaac Sasson, Orkan Ilbay, Denny Sakkas, Katie M. Lowther, Lisa M. Mehlmann and Emre Seli..........47‑58
- Published as BJ Immediate Publication 24 May 2012, doi:10.1042/BJ20120467
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- Redox properties of the disulfide bond of human Cu,Zn superoxide dismutase and the effects of human glutaredoxin 1
- Samantha D. Bouldin, Maxwell A. Darch, P. John Hart and Caryn E. Outten..........59‑67
- Published as BJ Immediate Publication 31 May 2012, doi:10.1042/BJ20120075
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- Revealing a natural marine product as a novel agonist for retinoic acid receptors with a unique binding mode and inhibitory effects on cancer cells
- Shanshan Wang, Zhao Wang, Shengchen Lin, Weili Zheng, Rui Wang, Shikai Jin, Jinan Chen, Lihua Jin and Yong Li..........79‑87
- Published as BJ Immediate Publication 29 May 2012, doi:10.1042/BJ20120726
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- Upstream stimulatory factor 1 activates GATA5 expression through an E-box motif
- Bohao Chen, Rona Hsu, Zhenping Li, Paul C. Kogut, Qingxia Du, Kelly Rouser, Blanca Camoretti‑Mercado and Julian Solway..........89‑98
- Published as BJ Immediate Publication 25 May 2012, doi:10.1042/BJ20111942
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- The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation
- Iakov N. Rudenko, Alice Kaganovich, David N. Hauser, Aleksandra Beylina, Ruth Chia, Jinhui Ding, Dragan Maric, Howard Jaffe and Mark R. Cookson..........99‑111
- Published as BJ Immediate Publication 22 May 2012, doi:10.1042/BJ20120637
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- Desulfovibrio vulgaris bacterioferritin uses H2O2 as a co-substrate for iron oxidation and reveals DPS-like DNA protection and binding activities
- Cristina G. Timóteo, Márcia Guilherme, Daniela Penas, Filipe Folgosa, Pedro Tavares and Alice S. Pereira..........125‑133
- Published as BJ Immediate Publication 29 May 2012, doi:10.1042/BJ20111439
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Intestinal peptidases form functional complexes with the neutral amino acid transporter B0AT1
- Stephen J. Fairweather, Angelika Bröer, Megan L. O'Mara and Stefan Bröer..........135‑148
- Published as BJ Immediate Publication 7 June 2012, doi:10.1042/BJ20120307
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Volume 445
- A key structural domain of the Candida albicans Mdr1 protein
- Ajeet Mandal, Antresh Kumar, Ashutosh Singh, Andrew M. Lynn, Khyati Kapoor and Rajendra Prasad..........313‑322
- Published as BJ Immediate Publication 16 May 2012, doi:10.1042/BJ20120190
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- p130Cas-dependent actin remodelling regulates myogenic differentiation
- Keiko Kawauchi, Wee Wee Tan, Keigo Araki, Farhana Binte Abu Bakar, Minsoo Kim, Hideaki Fujita, Hiroaki Hirata and Yasuhiro Sawada..........323‑332
- Published as BJ Immediate Publication 15 May 2012, doi:10.1042/BJ20112169
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- Glutathionylation of cytosolic glyceraldehyde-3-phosphate dehydrogenase from the model plant Arabidopsis thaliana is reversed by both glutaredoxins and thioredoxins in vitro
- Mariette Bedhomme, Mattia Adamo, Christophe H. Marchand, Jérémy Couturier, Nicolas Rouhier, Stéphane D. Lemaire, Mirko Zaffagnini and Paolo Trost..........337‑347
- Published as BJ Immediate Publication 21 May 2012, doi:10.1042/BJ20120505
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Solution structure of the core SMN–Gemin2 complex
- Kathryn L. Sarachan, Kathleen G. Valentine, Kushol Gupta, Veronica R. Moorman, John M. Gledhill, Matthew Bernens, Cecilia Tommos, A. Joshua Wand and Gregory D. Van Duyne..........361‑370
- Published as BJ Immediate Publication 21 May 2012, doi:10.1042/BJ20120241
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Nitric oxide-dependent CYP2B degradation is potentiated by a cytokine-regulated pathway and utilizes the immunoproteasome subunit LMP2
- Haiyan Sun, Choon‑myung Lee, Shweta Tripathi, Kyung‑Bo Kim and Edward T. Morgan..........377‑382
- Published as BJ Immediate Publication 22 May 2012, doi:10.1042/BJ20120820
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- Recruitment and membrane interactions of host cell proteins during attachment of enteropathogenic and enterohaemorrhagic Escherichia coli
- Diana Munera, Eric Martinez, Svetlana Varyukhina, Arvind Mahajan, Jesus Ayala‑Sanmartin and Gad Frankel..........383‑392
- Published as BJ Immediate Publication 16 May 2012, doi:10.1042/BJ20120533
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TGF-β sensitivity is determined by N-linked glycosylation of the type II TGF-β receptor
- Young‑Woong Kim, Jinah Park, Hyun‑Ju Lee, So‑Young Lee and Seong‑Jin Kim..........403‑411
- Published as BJ Immediate Publication 10 May 2012, doi:10.1042/BJ20111923
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- Mutational analysis of putative phosphate- and proton-binding sites in the Saccharomyces cerevisiae Pho84 phosphate:H+ transceptor and its effect on signalling to the PKA and PHO pathways
- Dieter R. Samyn, Lorena Ruiz‑Pávon, Michael R. Andersson, Yulia Popova, Johan M. Thevelein and Bengt L. Persson..........413‑422
- Published as BJ Immediate Publication 15 May 2012, doi:10.1042/BJ20112086
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- Thioredoxin reductase 1 deficiency enhances selenite toxicity in cancer cells via a thioredoxin-independent mechanism
- Ryuta Tobe, Min‑Hyuk Yoo, Noelia Fradejas, Bradley A. Carlson, Soledad Calvo, Vadim N. Gladyshev and Dolph L. Hatfield..........423‑430
- Published as BJ Immediate Publication 17 May 2012, doi:10.1042/BJ20120618
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- The MEKK1 SWIM domain is a novel substrate receptor for c-Jun ubiquitylation
- Michael A. Rieger, Tyler Duellman, Christopher Hooper, Magdalene Ameka, Joanna C. Bakowska and Bruce D. Cuevas..........431‑439
- Published as BJ Immediate Publication 14 May 2012, doi:10.1042/BJ20120406
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- A key role for Mg2+ in TRPM7's control of ROS levels during cell stress
- Hsiang‑Chin Chen, Li‑Ting Su, Omayra González‑Pagán, Jeffrey D. Overton and Loren W. Runnels..........441‑448
- Published as BJ Immediate Publication 15 May 2012, doi:10.1042/BJ20120248
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- A urea channel from Bacillus cereus reveals a novel hexameric structure
- Gerard H. M. Huysmans, Nathan Chan, Jocelyn M. Baldwin, Vincent L. G. Postis, Svetomir B. Tzokov, Sarah E. Deacon, Sylvia Y. M. Yao, James D. Young, Michael J. McPherson, Per A. Bullough and Stephen A. Baldwin..........157‑166
- Published as BJ Immediate Publication 3 May 2012, doi:10.1042/BJ20120169
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- Architecture of the catalytic HPN motif is conserved in all E2 conjugating enzymes
- Benjamin W. Cook and Gary S. Shaw..........167‑174
- Published as BJ Immediate Publication 8 May 2012, doi:10.1042/BJ20120504
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- The crystal structure of human α1-microglobulin reveals a potential haem-binding site
- Winfried Meining and Arne Skerra..........175‑182
- Published as BJ Immediate Publication 19 April 2012, doi:10.1042/BJ20120448
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- Structure and activity of the cold-active and anion-activated carboxyl esterase OLEI01171 from the oil-degrading marine bacterium Oleispira antarctica
- Sofia Lemak, Anatoli Tchigvintsev, Pierre Petit, Robert Flick, Alexander U. Singer, Greg Brown, Elena Evdokimova, Olga Egorova, Claudio F. Gonzalez, Tatyana N. Chernikova, Michail M. Yakimov, Michael Kube, Richard Reinhardt, Peter N. Golyshin, Alexei Savchenko and Alexander F. Yakunin..........193‑203
- Published as BJ Immediate Publication 23 April 2012, doi:10.1042/BJ20112113
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- The saposin-like protein SPP-12 is an antimicrobial polypeptide in the pharyngeal neurons of Caenorhabditis elegans and participates in defence against a natural bacterial pathogen
- Aylin Hoeckendorf, Mareike Stanisak and Matthias Leippe..........205‑212
- Published as BJ Immediate Publication 23 April 2012, doi:10.1042/BJ20112102
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- Distinct functional roles of the two terminal halves of eukaryotic phosphofructokinase
- Oscar H. Martínez‑Costa, Valentina Sánchez, Antonio Lázaro, Eloy D. Hernández, Keith Tornheim and Juan J. Aragón..........213‑218
- Published as BJ Immediate Publication 25 April 2012, doi:10.1042/BJ20120173
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- Characterization of an acetyltransferase that detoxifies aromatic chemicals in Legionella pneumophila
- Xavier Kubiak, Delphine Dervins‑Ravault, Benjamin Pluvinage, Alain F. Chaffotte, Laura Gomez‑Valero, Julien Dairou, Florent Busi, Jean‑Marie Dupret, Carmen Buchrieser and Fernando Rodrigues‑Lima..........219‑228
- Published as BJ Immediate Publication 30 April 2012, doi:10.1042/BJ20120528
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Different molecular bases underlie the mitochondrial respiratory activity in the homoeothermic spadices of Symplocarpus renifolius and the transiently thermogenic appendices of Arum maculatum
- Yusuke Kakizaki, Anthony L. Moore and Kikukatsu Ito..........237‑246
- Published as BJ Immediate Publication 19 April 2012, doi:10.1042/BJ20111978
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- Mitochondrial stress causes increased succination of proteins in adipocytes in response to glucotoxicity
- Norma Frizzell, Sonia A. Thomas, James A. Carson and John W. Baynes..........247‑254
- Published as BJ Immediate Publication 24 April 2012, doi:10.1042/BJ20112142
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- The activation mechanism of ACK1 (activated Cdc42-associated tyrosine kinase 1)
- Qiong Lin, Jian Wang, Chandra Childress and Wannian Yang..........255‑264
- Published as BJ Immediate Publication 3 May 2012, doi:10.1042/BJ20111575
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- Deciphering the role of GLUT4 N-glycosylation in adipocyte and muscle cell models
- Nancy Zaarour, Marion Berenguer, Yannick Le Marchand‑Brustel and Roland Govers..........265‑273
- Published as BJ Immediate Publication 30 April 2012, doi:10.1042/BJ20120232
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- Cysteine biosynthesis, in concert with a novel mechanism, contributes to sulfide detoxification in mitochondria of Arabidopsis thaliana
- Hannah Birke, Florian H. Haas, Luit J. De Kok, Janneke Balk, Markus Wirtz and Rüdiger Hell..........275‑283
- Published as BJ Immediate Publication 2 May 2012, doi:10.1042/BJ20120038
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- The human NUPR1/P8 gene is transcriptionally activated by transforming growth factor β via the SMAD signalling pathway
- Roxane M. Pommier, Johann Gout, David F. Vincent, Carla E. Cano, Bastien Kaniewski, Sylvie Martel, Jonathan Rodriguez, Geneviève Fourel, Ulrich Valcourt, Julien C. Marie, Juan L. Iovanna and Laurent Bartholin..........285‑293
- Published as BJ Immediate Publication 27 June 2012, doi:10.1042/BJ20120368
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- Multidimensional epistasis and fitness landscapes in enzyme evolution
- Wei Zhang, Daniel F. A. R. Dourado, Pedro Alexandrino Fernandes, Maria João Ramos and Bengt Mannervik..........39‑46
- Published as BJ Immediate Publication 26 April 2012, doi:10.1042/BJ20120136
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- Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor
- Ilaria Lamberto, Haina Qin, Roberta Noberini, Lakshmanane Premkumar, Caroline Bourgin, Stefan J. Riedl, Jianxing Song and Elena B. Pasquale..........47‑56
- Published as BJ Immediate Publication 10 April 2012, doi:10.1042/BJ20120408
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- Neisseria meningitidis and Neisseria gonorrhoeae are differently adapted in the regulation of denitrification: single nucleotide polymorphisms that enable species-specific tuning of the aerobic–anaerobic switch
- James Edwards, Diana Quinn, Karyn‑Anne Rowbottom, Jean L. Whittingham, Melanie J. Thomson and James W. B. Moir..........69‑79
- Published as BJ Immediate Publication 18 April 2012, doi:10.1042/BJ20111984
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- Bax and Bcl-xL exert their regulation on different sites of the ceramide channel
- Meenu N. Perera, Shang H. Lin, Yuri K. Peterson, Alicja Bielawska, Zdzislaw M. Szulc, Robert Bittman and Marco Colombini..........81‑91
- Published as BJ Immediate Publication 11 April 2012, doi:10.1042/BJ20112103
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- Embryonic poly(A)-binding protein (ePAB) phosphorylation is required for Xenopus oocyte maturation
- Kyle Friend, Matthew Brook, F. Betül Bezirci, Michael D. Sheets, Nicola K. Gray and Emre Seli..........93‑100
- Published as BJ Immediate Publication 13 April 2012, doi:10.1042/BJ20120304
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- A conserved cysteine residue is involved in disulfide bond formation between plant plasma membrane aquaporin monomers
- Gerd P. Bienert, Damien Cavez, Arnaud Besserer, Marie C. Berny, Dimitri Gilis, Marianne Rooman and François Chaumont..........101‑111
- Published as BJ Immediate Publication 17 April 2012, doi:10.1042/BJ20111704
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- Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues
- Johan Vande Voorde, Federico Gago, Kristof Vrancken, Sandra Liekens and Jan Balzarini..........113‑123
- Published as BJ Immediate Publication 4 April 2012, doi:10.1042/BJ20112225
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- β2-Glycoprotein I inhibits endothelial cell migration through the nuclear factor κB signalling pathway and endothelial nitric oxide synthase activation
- Wen‑Chin Chiu, Tzeon‑Jye Chiou and An‑Na Chiang..........125‑133
- Published as BJ Immediate Publication 10 April 2012, doi:10.1042/BJ20111383
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- A novel bispecific single-chain antibody for ADAM17 and CD3 induces T-cell-mediated lysis of prostate cancer cells
- Kosuke Yamamoto, Ahmad Trad, Anja Baumgart, Linda Hüske, Inken Lorenzen, Athena Chalaris, Joachim Grötzinger, Tobias Dechow, Jürgen Scheller and Stefan Rose‑John..........135‑144
- Published as BJ Immediate Publication 17 April 2012, doi:10.1042/BJ20120433
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Volume 444
- EHD2 shuttles to the nucleus and represses transcription
- Olga Pekar, Sigi Benjamin, Hilla Weidberg, Silvia Smaldone, Francesco Ramirez and Mia Horowitz..........383‑394
- Published as BJ Immediate Publication 26 March 2012, doi:10.1042/BJ20111268
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- DNA binding by the plant-specific NAC transcription factors in crystal and solution: a firm link to WRKY and GCM transcription factors
- Ditte H. Welner, Søren Lindemose, J. Günter Grossmann, Niels Erik Møllegaard, Addie N. Olsen, Charlotte Helgstrand, Karen Skriver and Leila Lo Leggio..........395‑404
- Published as BJ Immediate Publication 29 March 2012, doi:10.1042/BJ20111742
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- The disordered N-terminal region of dengue virus capsid protein contains a lipid-droplet-binding motif
- Ivo C. Martins, Francisco Gomes‑Neto, André F. Faustino, Filomena A. Carvalho, Fabiana A. Carneiro, Patricia T. Bozza, Ronaldo Mohana‑Borges, Miguel A. R. B. Castanho, Fábio C. L. Almeida, Nuno C. Santos and Andrea T. Da Poian..........405‑415
- Published as BJ Immediate Publication 19 March 2012, doi:10.1042/BJ20112219
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- Bivalent and co-operative binding of complement Factor H to heparan sulfate and heparin
- Sanaullah Khan, Ruodan Nan, Jayesh Gor, Barbara Mulloy and Stephen J. Perkins..........417‑428
- Published as BJ Immediate Publication 3 April 2012, doi:10.1042/BJ20120183
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Glycosylation at Asn91 of H1N1 haemagglutinin affects binding to glycan receptors
- Akila Jayaraman, Xiaoying Koh, Jing Li, Rahul Raman, Karthik Viswanathan, Zachary Shriver and Ram Sasisekharan..........429‑435
- Published as BJ Immediate Publication 29 May 2012, doi:10.1042/BJ20112101
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- A glycosynthase derived from an inverting GH19 chitinase from the moss Bryum coronatum
- Takayuki Ohnuma, Tatsuya Fukuda, Satoshi Dozen, Yuji Honda, Motomitsu Kitaoka and Tamo Fukamizo..........437‑443
- Published as BJ Immediate Publication 21 March 2012, doi:10.1042/BJ20120036
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- Structure and activity of the Pseudomonas aeruginosa hotdog-fold thioesterases PA5202 and PA2801
- Claudio F. Gonzalez, Anatoli Tchigvintsev, Greg Brown, Robert Flick, Elena Evdokimova, Xiaohui Xu, Jerzy Osipiuk, Marianne E. Cuff, Susan Lynch, Andrzej Joachimiak, Alexei Savchenko and Alexander F. Yakunin..........445‑455
- Published as BJ Immediate Publication 23 March 2012, doi:10.1042/BJ20112032
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- A functional description of CymA, an electron-transfer hub supporting anaerobic respiratory flexibility in Shewanella
- Sophie J. Marritt, Thomas G. Lowe, Jordan Bye, Duncan G. G. McMillan, Liang Shi, Jim Fredrickson, John Zachara, David J. Richardson, Myles R. Cheesman, Lars J. C. Jeuken and Julea N. Butt..........465‑474
- Published as BJ Immediate Publication 29 March 2012, doi:10.1042/BJ20120197
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- The Candida albicans plasma membrane protein Rch1p, a member of the vertebrate SLC10 carrier family, is a novel regulator of cytosolic Ca2+ homoeostasis
- Linghuo Jiang, Joerg Alber, Jihong Wang, Wei Du, Xuexue Yang, Xichuan Li, Dominique Sanglard and Joachim Geyer..........497‑502
- Published as BJ Immediate Publication 24 April 2012, doi:10.1042/BJ20112166
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Interleukin-6 counteracts therapy-induced cellular oxidative stress in multiple myeloma by up-regulating manganese superoxide dismutase
- Charles O. Brown, Kelley Salem, Brett A. Wagner, Soumen Bera, Neeraj Singh, Ajit Tiwari, Amit Choudhury, Garry R. Buettner and Apollina Goel..........515‑527
- Published as BJ Immediate Publication 3 April 2012, doi:10.1042/BJ20112019
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- Definition of the binding mode of a new class of phosphoinositide 3-kinase α-selective inhibitors using in vitro mutagenesis of non-conserved amino acids and kinetic analysis
- Zhaohua Zheng, Syazwani I. Amran, Jiuxiang Zhu, Oleg Schmidt‑Kittler, Kenneth W. Kinzler, Bert Vogelstein, Peter R. Shepherd, Philip E. Thompson and Ian G. Jennings..........529‑535
- Published as BJ Immediate Publication 13 April 2012, doi:10.1042/BJ20120499
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- Effects of a glucokinase activator on hepatic intermediary metabolism: study with 13C-isotopomer-based metabolomics
- Itzhak Nissim, Oksana Horyn, Ilana Nissim, Yevgeny Daikhin, Suzanne L. Wehrli, Marc Yudkoff and Franz M. Matschinsky..........537‑551
- Published as BJ Immediate Publication 26 March 2012, doi:10.1042/BJ20120163
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- Pyruvate fuels mitochondrial respiration and proliferation of breast cancer cells: effect of monocarboxylate transporter inhibition
- Anne R. Diers, Katarzyna A. Broniowska, Ching‑Fang Chang and Neil Hogg..........561‑571
- Published as BJ Immediate Publication 30 March 2012, doi:10.1042/BJ20120294
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- DNAJB6 governs a novel regulatory loop determining Wnt/β-catenin signalling activity
- Mitchell E. Menezes, Aparna Mitra, Lalita A. Shevde and Rajeev S. Samant..........573‑580
- Published as BJ Immediate Publication 28 March 2012, doi:10.1042/BJ20120205
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- Oestrogen causes ATBF1 protein degradation through the oestrogen-responsive E3 ubiquitin ligase EFP
- Xue‑Yuan Dong, Xiaoying Fu, Songqing Fan, Peng Guo, Dan Su and Jin‑Tang Dong..........581‑590
- Published as BJ Immediate Publication 28 March 2012, doi:10.1042/BJ20111890
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Neuronal caspase 2 activity and function requires RAIDD, but not PIDD
- Elena M. Ribe, Ying Y. Jean, Rebecca L. Goldstein, Claudia Manzl, Leonidas Stefanis, Andreas Villunger and Carol M. Troy..........591‑599
- Published as BJ Immediate Publication 19 April 2012, doi:10.1042/BJ20111588
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- Synthesis of inositol phosphate ligands of plant hormone–receptor complexes: pathways of inositol hexakisphosphate turnover
- David E. Hanke, Paroo N. Parmar, Samuel E. K. Caddick, Porntip Green and Charles A. Brearley..........601‑609
- Published as BJ Immediate Publication 20 March 2012, doi:10.1042/BJ20111811
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- Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate
- Marcella Ma, Heather P. Harding, Stephen O'Rahilly, David Ron and Giles S. H. Yeo..........183‑187
- Published as BJ Immediate Publication 21 March 2012, doi:10.1042/BJ20120065
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- Construction of histidine-tagged yeast mitochondrial cytochrome c oxidase for facile purification of mutant forms
- Brigitte Meunier, Amandine Maréchal and Peter R. Rich..........199‑204
- Published as BJ Immediate Publication 7 March 2012, doi:10.1042/BJ20120116
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- Involvement of TSSA (trypomastigote small surface antigen) in Trypanosoma cruzi invasion of mammalian cells1
- Gaspar E. Cánepa, Maria Sol Degese, Alexandre Budu, Celia R. S. Garcia and Carlos A. Buscaglia..........211‑218
- Published as BJ Immediate Publication 20 March 2012, doi:10.1042/BJ20120074
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- Characterization of a novel copper-haem c dissimilatory nitrite reductase from Ralstonia pickettii
- Cong Han, Gareth S. A. Wright, Karl Fisher, Stephen E. J. Rigby, Robert R. Eady and S. Samar Hasnain..........219‑226
- Published as BJ Immediate Publication 13 March 2012, doi:10.1042/BJ20111623
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- Characterization of the evolutionarily conserved iron–sulfur cluster of sirohydrochlorin ferrochelatase from Arabidopsis thaliana
- Kaushik Saha, Michael E. Webb, Stephen E. J. Rigby, Helen K. Leech, Martin J. Warren and Alison G. Smith..........227‑237
- Published as BJ Immediate Publication 13 March 2012, doi:10.1042/BJ20111993
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- Cyanide is an adequate agonist of the plant hormone ethylene for studying signalling of sensor kinase ETR1 at the molecular level
- Melanie M. A. Bisson and Georg Groth..........261‑267
- Published as BJ Immediate Publication 5 March 2012, doi:10.1042/BJ20111447
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- Kinetics of Torpedo californica acetylcholinesterase inhibition by bisnorcymserine and crystal structure of the complex with its leaving group
- Cecilia Bartolucci, Jure Stojan, Qian‑sheng Yu, Nigel H. Greig and Doriano Lamba..........269‑277
- Published as BJ Immediate Publication 6 March 2012, doi:10.1042/BJ20111675
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- JNK- and Akt-mediated Puma expression in the apoptosis of cisplatin-resistant ovarian cancer cells
- Zhiwei Zhao, Jingjing Wang, Jingsheng Tang, Xinyu Liu, Qian Zhong, Fang Wang, Wenbin Hu, Zhu Yuan, Chunlai Nie and Yuquan Wei..........291‑301
- Published as BJ Immediate Publication 7 March 2012, doi:10.1042/BJ20111855
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- Golgi-SNARE GS28 potentiates cisplatin-induced apoptosis by forming GS28–MDM2–p53 complexes and by preventing the ubiquitination and degradation of p53
- Nian‑Kang Sun, Shang‑Lang Huang, Kun‑Yi Chien and Chuck C.‑K. Chao..........303‑314
- Published as BJ Immediate Publication 8 March 2012, doi:10.1042/BJ20112223
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- CARM1/PRMT4 is necessary for the glycogen gene expression programme in skeletal muscle cells
- Shu‑Ching Mary Wang, Dennis H. Dowhan, Natalie A. Eriksson and George E. O. Muscat..........323‑331
- Published as BJ Immediate Publication 19 March 2012, doi:10.1042/BJ20112033
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Feedback regulation by Atf3 in the endothelin-1-responsive transcriptome of cardiomyocytes: Egr1 is a principal Atf3 target
- Alejandro Giraldo, Oliver P. T. Barrett, Marcus J. Tindall, Stephen J. Fuller, Emre Amirak, Bonhi S. Bhattacharya, Peter H. Sugden and Angela Clerk..........343‑355
- Published as BJ Immediate Publication 5 March 2012, doi:10.1042/BJ20120125
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- Ligand-activated PPARδ inhibits UVB-induced senescence of human keratinocytes via PTEN-mediated inhibition of superoxide production
- Sun Ah Ham, Jung Seok Hwang, Taesik Yoo, Hanna Lee, Eun Sil Kang, Chankyu Park, Jae‑Wook Oh, Hoon Taek Lee, Gyesik Min, Jin‑Hoi Kim and Han Geuk Seo..........27‑38
- Published as BJ Immediate Publication 16 February 2012, doi:10.1042/BJ20111832
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- The role of the Snf1 kinase in the adaptive response of Saccharomyces cerevisiae to alkaline pH stress
- Antonio Casamayor, Raquel Serrano, María Platara, Carlos Casado, Amparo Ruiz and Joaquín Ariño..........39‑49
- Published as BJ Immediate Publication 28 February 2012, doi:10.1042/BJ20112099
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- Copper redistribution in murine macrophages in response to Salmonella infection
- Maud E. S. Achard, Sian L. Stafford, Nilesh J. Bokil, Jy Chartres, Paul V. Bernhardt, Mark A. Schembri, Matthew J. Sweet and Alastair G. McEwan..........51‑57
- Published as BJ Immediate Publication 28 February 2012, doi:10.1042/BJ20112180
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- The Bcl-2 proteins Noxa and Bcl-xL co-ordinately regulate oxidative stress-induced apoptosis
- Colins O. Eno, Guoping Zhao, Kristen E. Olberding and Chi Li..........69‑78
- Published as BJ Immediate Publication 1 March 2012, doi:10.1042/BJ20112023
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- Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1
- Mark E. Schnute, Matthew D. McReynolds, Tom Kasten, Matthew Yates, Gina Jerome, John W. Rains, Troii Hall, Jill Chrencik, Michelle Kraus, Ciaran N. Cronin, Matthew Saabye, Maureen K. Highkin, Richard Broadus, Shinji Ogawa, Kristin Cukyne, Laura E. Zawadzke, Vincent Peterkin, Kaliapan Iyanar, Jeffrey A. Scholten, Jay Wendling, Hideji Fujiwara, Olga Nemirovskiy, Arthur J. Wittwer and Marek M. Nagiec..........79‑88
- Published as BJ Immediate Publication 8 March 2012, doi:10.1042/BJ20111929
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Coronin 1C harbours a second actin-binding site that confers co-operative binding to F-actin
- Keefe T. Chan, David W. Roadcap, Nicholas Holoweckyj and James E. Bear..........89‑96
- Published as BJ Immediate Publication 27 February 2012, doi:10.1042/BJ20120209
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- The oligomer plasticity of the small heat-shock protein Lo18 from Oenococcus oeni influences its role in both membrane stabilization and protein protection
- Magali Maitre, Stéphanie Weidmann, Aurélie Rieu, Daphna Fenel, Guy Schoehn, Christine Ebel, Jacques Coves and Jean Guzzo..........97‑104
- Published as BJ Immediate Publication 24 February 2012, doi:10.1042/BJ20120066
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- A new validated mathematical model of the Wnt signalling pathway predicts effective combinational therapy by sFRP and Dkk
- Yuri Kogan, Karin E. Halevi‑Tobias, Gili Hochman, Anna K. Baczmanska, Luc Leyns and Zvia Agur..........115‑125
- Published as BJ Immediate Publication 22 February 2012, doi:10.1042/BJ20111887
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- Stable isotope-labelling analysis of the impact of inhibition of the mammalian target of rapamycin on protein synthesis
- Yilin Huo, Valentina Iadevaia, Zhong Yao, Isabelle Kelly, Sabina Cosulich, Sylvie Guichard, Leonard J. Foster and Christopher G. Proud..........141‑151
- Published as BJ Immediate Publication 19 March 2012, doi:10.1042/BJ20112107
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Volume 443
- Mutual co-regulation between GPI-N-acetylglucosaminyltransferase and ergosterol biosynthesis in Candida albicans
- Guiliana Soraya Victoria, Bhawna Yadav, Lalremruata Hauhnar, Priyanka Jain, Shilpi Bhatnagar and Sneha Sudha Komath..........619‑625
- Published as BJ Immediate Publication 5 March 2012, doi:10.1042/BJ20120143
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- An activity-based probe reveals dynamic protein–protein interactions mediating IGF-1R transactivation by the GABAB receptor
- Xin Lin, Xin Li, Ming Jiang, Linhai Chen, Chanjuan Xu, Wenhua Zhang, Han Zhao, Bing Sun, Xiaoli Xu, Fajun Nan and Jianfeng Liu..........627‑634
- Published as BJ Immediate Publication 7 March 2012, doi:10.1042/BJ20120188
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- Readthrough of long-QT syndrome type 1 nonsense mutations rescues function but alters the biophysical properties of the channel
- Stephen C. Harmer, Jagdeep S. Mohal, Duncan Kemp and Andrew Tinker..........635‑642
- Published as BJ Immediate Publication 6 February 2012, doi:10.1042/BJ20111912
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- Identification of the topology and functional domains of PAQR10
- Ting Jin, Daqian Xu, Qiurong Ding, Yixuan Zhang, Chenqian Mao, Yi Pan, Zhenzhen Wang and Yan Chen..........643‑653
- Published as BJ Immediate Publication 17 February 2012, doi:10.1042/BJ20112105
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- Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1
- Iain Scott, Bradley R. Webster, Jian H. Li and Michael N. Sack..........655‑661
- Published as BJ Immediate Publication 6 February 2012, doi:10.1042/BJ20120118
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- Role of individual phosphorylation sites for the 14-3-3-protein-dependent activation of yeast neutral trehalase Nth1
- Dana Veisova, Eva Macakova, Lenka Rezabkova, Miroslav Sulc, Petr Vacha, Hana Sychrova, Tomas Obsil and Veronika Obsilova..........663‑670
- Published as BJ Immediate Publication 9 February 2012, doi:10.1042/BJ20111615
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- Crystal structure of the enzyme CapF of Staphylococcus aureus reveals a unique architecture composed of two functional domains
- Takamitsu Miyafusa, Jose M. M. Caaveiro, Yoshikazu Tanaka and Kouhei Tsumoto..........671‑680
- Published as BJ Immediate Publication 9 February 2012, doi:10.1042/BJ20112049
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- Cross-talk between TGFβ1 and EGFR signalling pathways induces TM4SF5 expression and epithelial–mesenchymal transition
- Minkyung Kang, Suyong Choi, Soo‑Jin Jeong, Sin‑Ae Lee, Tae Kyoung Kwak, Hyeonjung Kim, Oisun Jung, Mi‑Sook Lee, Youra Ko, Jihye Ryu, Yoon‑Ju Choi, Doyoung Jeong, Hyo Jeong Lee, Sang‑Kyu Ye, Sung‑Hoon Kim and Jung Weon Lee..........691‑700
- Published as BJ Immediate Publication 31 January 2012, doi:10.1042/BJ20111584
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- CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells
- Ke Gong, Jia Xie, Hong Yi and Wenhua Li..........735‑746
- Published as BJ Immediate Publication 17 February 2012, doi:10.1042/BJ20111685
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- The novel function of HINFP as a co-activator in sterol-regulated transcription of PCSK9 in HepG2 cells
- Hai Li and Jingwen Liu..........757‑768
- Published as BJ Immediate Publication 31 January 2012, doi:10.1042/BJ20111645
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- Transthyretin is a metallopeptidase with an inducible active site
- Márcia A. Liz, Sérgio C. Leite, Luiz Juliano, Maria J. Saraiva, Ana M. Damas, Daniel Bur and Mónica M. Sousa..........769‑778
- Published as BJ Immediate Publication 15 February 2012, doi:10.1042/BJ20111690
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- The mouse Mageb18 gene encodes a ubiquitously expressed type I MAGE protein and regulates cell proliferation and apoptosis in melanoma B16-F0 cells
- Yuquan Lin, Ti Wen, Xianyi Meng, Zhenzhou Wu, Liqing Zhao, Puyue Wang, Zhangyong Hong and Zhinan Yin..........779‑788
- Published as BJ Immediate Publication 15 February 2012, doi:10.1042/BJ20112054
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- p53 Ser15 phosphorylation disrupts the p53–RPA70 complex and induces RPA70-mediated DNA repair in hypoxia
- Esha Madan, Rajan Gogna and Uttam Pati..........811‑820
- Published as BJ Immediate Publication 30 January 2012, doi:10.1042/BJ20111627
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Induction of NANOG expression by targeting promoter sequence with small activating RNA antagonizes retinoic acid-induced differentiation
- Xiaoling Wang, Ji Wang, Vera Huang, Robert F. Place and Long‑Cheng Li..........821‑828
- Published as BJ Immediate Publication 17 February 2012, doi:10.1042/BJ20111491
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- The ligand specificity of the G-protein-coupled receptor GPR34
- Lars Ritscher, Eva Engemaier, Claudia Stäubert, Ines Liebscher, Philipp Schmidt, Thomas Hermsdorf, Holger Römpler, Angela Schulz and Torsten Schöneberg..........841‑850
- Published as BJ Immediate Publication 20 February 2012, doi:10.1042/BJ20112090
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Isoform-selective induction of human p110δ PI3K expression by TNFα: identification of a new and inducible PIK3CD promoter
- Maria A. Whitehead, Michele Bombardieri, Costantino Pitzalis and Bart Vanhaesebroeck..........857‑867
- Published as BJ Immediate Publication 29 February 2012, doi:10.1042/BJ20112214
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A novel lectin from Agrocybe aegerita shows high binding selectivity for terminal N-acetylglucosamine
- Shuai Jiang, Yijie Chen, Man Wang, Yalin Yin, Yongfu Pan, Bianli Gu, Guojun Yu, Yamu Li, Barry Hon Cheung Wong, Yi Liang and Hui Sun..........369‑378
- Published as BJ Immediate Publication 23 January 2012, doi:10.1042/BJ20112061
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- The non-steroidal anti-inflammatory drug indomethacin activates the eIF2α kinase PKR, causing a translational block in human colorectal cancer cells
- Claudia Brunelli, Carla Amici, Mara Angelini, Chiara Fracassi, Giuseppe Belardo and M. Gabriella Santoro..........379‑386
- Published as BJ Immediate Publication 23 January 2012, doi:10.1042/BJ20111236
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- The Golgi-associated long coiled-coil protein NECC1 participates in the control of the regulated secretory pathway in PC12 cells
- David Cruz‑García, Alberto Díaz‑Ruiz, Yoana Rabanal‑Ruiz, Juan R. Peinado, Francisco Gracia‑Navarro, Justo P. Castaño, Maité Montero‑Hadjadje, Marie‑Christine Tonon, Hubert Vaudry, Youssef Anouar, Rafael Vázquez‑Martínez and María M. Malagón..........387‑396
- Published as BJ Immediate Publication 18 January 2012, doi:10.1042/BJ20110554
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- Transforming growth factor β1 represses proximal tubular cell microRNA-192 expression through decreased hepatocyte nuclear factor DNA binding
- Robert H. Jenkins, John Martin, Aled O. Phillips, Timothy Bowen and Donald J. Fraser..........407‑416
- Published as BJ Immediate Publication 23 January 2012, doi:10.1042/BJ20111861
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- Regulation of the intersubunit ammonia tunnel in Mycobacterium tuberculosis glutamine-dependent NAD+ synthetase
- Watchalee Chuenchor, Tzanko I. Doukov, Melissa Resto, Andrew Chang and Barbara Gerratana..........417‑426
- Published as BJ Immediate Publication 26 January 2012, doi:10.1042/BJ20112210
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- Crystal structure and functional characterization of a glucosamine-6-phosphate N-acetyltransferase from Arabidopsis thaliana
- Heike Riegler, Thomas Herter, Irina Grishkovskaya, Anja Lude, Malgorzata Ryngajllo, Marie E. Bolger, Bernd Essigmann and Björn Usadel..........427‑437
- Published as BJ Immediate Publication 13 February 2012, doi:10.1042/BJ20112071
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- γ-Enolase C-terminal peptide promotes cell survival and neurite outgrowth by activation of the PI3K/Akt and MAPK/ERK signalling pathways
- Anja Hafner, Nataša Obermajer and Janko Kos..........439‑450
- Published as BJ Immediate Publication 19 January 2012, doi:10.1042/BJ20111351
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- CNGA3 is expressed in inner ear hair cells and binds to an intracellular C-terminus domain of EMILIN1
- Dakshnamurthy Selvakumar, Marian J. Drescher, Jayme R. Dowdall, Khalid M. Khan, James S. Hatfield, Neeliyath A. Ramakrishnan and Dennis G. Drescher..........463‑476
- Published as BJ Immediate Publication 17 January 2012, doi:10.1042/BJ20111255
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- A naturally occurring nonapeptide functionally compensates for the CP1 domain of leucyl-tRNA synthetase to modulate aminoacylation activity
- Min Tan, Wei Yan, Ru‑Juan Liu, Meng Wang, Xin Chen, Xiao‑Long Zhou and En‑Duo Wang..........477‑484
- Published as BJ Immediate Publication 1 February 2012, doi:10.1042/BJ20111925
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3′-5′ Phosphoadenosine phosphate is an inhibitor of PARP-1 and a potential mediator of the lithium-dependent inhibition of PARP-1 in vivo
- Elie Toledano, Vasily Ogryzko, Antoine Danchin, Daniel Ladant and Undine Mechold..........485‑490
- Published as BJ Immediate Publication 12 January 2012, doi:10.1042/BJ20111057
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- Fibulin-5 binds urokinase-type plasminogen activator and mediates urokinase-stimulated β1-integrin-dependent cell migration
- Alexander Kapustin, Victoria Stepanova, Natalia Aniol, Douglas B. Cines, Alexei Poliakov, Serge Yarovoi, Tatiana Lebedeva, Robin Wait, Grigory Ryzhakov, Yelena Parfyonova, Yaroslav Gursky, Hiromi Yanagisawa, Mikhail Minashkin, Robert Beabealashvilli, Alexander Vorotnikov, Alex Bobik and Vsevolod Tkachuk..........491‑503
- Published as BJ Immediate Publication 26 January 2012, doi:10.1042/BJ20110348
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- Oxygen activation in neuronal NO synthase: resolving the consecutive mono-oxygenation steps
- Davide Papale, Chiara Bruckmann, Ben Gazur, Caroline S. Miles, Christopher G. Mowat and Simon Daff..........505‑514
- Published as BJ Immediate Publication 3 February 2012, doi:10.1042/BJ20111644
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Calcium/calmodulin inhibition of the Arabidopsis BRASSINOSTEROID-INSENSITIVE 1 receptor kinase provides a possible link between calcium and brassinosteroid signalling
- Man‑Ho Oh, Hyoung Seok Kim, Xia Wu, Steven D. Clouse, Raymond E. Zielinski and Steven C. Huber..........515‑523
- Published as BJ Immediate Publication 7 February 2012, doi:10.1042/BJ20111871
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Novel structural arrangement of nematode cystathionine β-synthases: characterization of Caenorhabditis elegans CBS-1
- Roman Vozdek, Aleš Hnízda, Jakub Krijt, Marta Kostrouchová and Viktor Kožich..........535‑547
- Published as BJ Immediate Publication 13 January 2012, doi:10.1042/BJ20111478
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- First identification of small-molecule inhibitors of Pontin by combining virtual screening and enzymatic assay
- Judith Elkaim, Michel Castroviejo, Driss Bennani, Said Taouji, Nathalie Allain, Michel Laguerre, Jean Rosenbaum, Jean Dessolin and Patrick Lestienne..........549‑559
- Published as BJ Immediate Publication 24 January 2012, doi:10.1042/BJ20111779
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- Regulation of human microsomal prostaglandin E synthase-1 by IL-1β requires a distal enhancer element with a unique role for C/EBPβ
- Jewell N. Walters, Justin S. Bickford, Kimberly J. Newsom, Dawn E. Beachy, Sarah J. Barilovits, John‑David Herlihy and Harry S. Nick..........561‑571
- Published as BJ Immediate Publication 20 January 2012, doi:10.1042/BJ20111801
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- Ribonucleoprotein Y-box-binding protein-1 regulates mitochondrial oxidative phosphorylation (OXPHOS) protein expression after serum stimulation through binding to OXPHOS mRNA
- Shinya Matsumoto, Takeshi Uchiumi, Hiroyuki Tanamachi, Toshiro Saito, Mikako Yagi, Shinya Takazaki, Tomotake Kanki and Dongchon Kang..........573‑584
- Published as BJ Immediate Publication 27 January 2012, doi:10.1042/BJ20111728
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- n−3 polyunsaturated fatty acids suppress phosphatidylinositol 4,5-bisphosphate-dependent actin remodelling during CD4+ T-cell activation
- Tim Y. Hou, Jennifer M. Monk, Yang‑Yi Fan, Rola Barhoumi, Yong Q. Chen, Gonzalo M. Rivera, David N. McMurray and Robert S. Chapkin..........27‑37
- Published as BJ Immediate Publication 18 January 2012, doi:10.1042/BJ20111589
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Structure–function studies of a plant tyrosyl-DNA phosphodiesterase provide novel insights into DNA repair mechanisms of Arabidopsis thaliana
- Hoyeun Kim, Sang Hyeon Na, So‑Young Lee, Young‑Min Jeong, Hyun‑Ju Hwang, Jae Young Hur, Sang‑Hyun Park, Je‑Chang Woo and Sang‑Gu Kim..........49‑56
- Published as BJ Immediate Publication 3 January 2012, doi:10.1042/BJ20111308
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- Lipocalin-type prostaglandin D synthase protects against oxidative stress-induced neuronal cell death
- Ayano Fukuhara, Mao Yamada, Ko Fujimori, Yuya Miyamoto, Toshihide Kusumoto, Hidemitsu Nakajima and Takashi Inui..........75‑84
- Published as BJ Immediate Publication 16 January 2012, doi:10.1042/BJ20111889
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- Biochemical identification of the OsMKK6–OsMPK3 signalling pathway for chilling stress tolerance in rice1
- Guosheng Xie, Hideki Kato and Ryozo Imai..........95‑102
- Published as BJ Immediate Publication 16 January 2012, doi:10.1042/BJ20111792
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- Serum copper as a novel biomarker for resistance to thyroid hormone
- Jens Mittag, Thomas Behrends, Kristina Nordström, Joao Anselmo, Björn Vennström and Lutz Schomburg..........103‑109
- Published as BJ Immediate Publication 6 January 2012, doi:10.1042/BJ20111817
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- The Q43L mutant of neuregulin 2β is a pan-ErbB receptor antagonist
- Kristy J. Wilson, Christopher P. Mill, Richard M. Gallo, Elizabeth M. Cameron, Henry VanBrocklin, Jeffrey Settleman and David J. Riese..........133‑144
- Published as BJ Immediate Publication 5 January 2012, doi:10.1042/BJ20110921
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- ROCKII Ser1366 phosphorylation reflects the activation status
- Hsiang‑Hao Chuang, Chih‑Hsuan Yang, Yeou‑Guang Tsay, Chih‑Yi Hsu, Ling‑Ming Tseng, Zee‑Fen Chang and Hsiao‑Hui Lee..........145‑151
- Published as BJ Immediate Publication 24 January 2012, doi:10.1042/BJ20111839
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- The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1α
- Mark A. Barber, Annick Hendrickx, Monique Beullens, Hugo Ceulemans, David Oxley, Sylvia Thelen, Marcus Thelen, Mathieu Bollen and Heidi C. E. Welch..........173‑183
- Published as BJ Immediate Publication 16 January 2012, doi:10.1042/BJ20112078
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- AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase
- Laurent Bultot, Bruno Guigas, Alexander Von Wilamowitz‑Moellendorff, Liliane Maisin, Didier Vertommen, Nusrat Hussain, Monique Beullens, Joan J. Guinovart, Marc Foretz, Benoît Viollet, Kei Sakamoto, Louis Hue and Mark H. Rider..........193‑203
- Published as BJ Immediate Publication 11 January 2012, doi:10.1042/BJ20112026
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- Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation
- Mingzhan Xue, Naila Rabbani, Hiroshi Momiji, Precious Imbasi, M. Maqsud Anwar, Neil Kitteringham, B. Kevin Park, Tomokazu Souma, Takashi Moriguchi, Masayuki Yamamoto and Paul J. Thornalley..........213‑222
- Published as BJ Immediate Publication 22 December 2011, doi:10.1042/BJ20111648
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- New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries
- Nunzianna Doti, Pasqualina L. Scognamiglio, Stefania Madonna, Claudia Scarponi, Menotti Ruvo, Giuseppe Perretta, Cristina Albanesi and Daniela Marasco..........231‑240
- Published as BJ Immediate Publication 14 December 2011, doi:10.1042/BJ20111647
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- Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms
- Craigen R. Nes, Ujjal K. Singha, Jialin Liu, Kulothungan Ganapathy, Fernando Villalta, Michael R. Waterman, Galina I. Lepesheva, Minu Chaudhuri and W. David Nes..........267‑277
- Published as BJ Immediate Publication 19 December 2011, doi:10.1042/BJ20111849
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Catalytic residues and a predicted structure of tetrahydrobiopterin-dependent alkylglycerol mono-oxygenase
- Katrin Watschinger, Julian E. Fuchs, Vladimir Yarov‑Yarovoy, Markus A. Keller, Georg Golderer, Albin Hermetter, Gabriele Werner‑Felmayer, Nicolas Hulo and Ernst R. Werner..........279‑286
- Published as BJ Immediate Publication 6 January 2012, doi:10.1042/BJ20111509
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- A critical tyrosine residue determines the uncoupling protein-like activity of the yeast mitochondrial oxaloacetate carrier
- Luis A. Luévano‑Martínez, Carlos Barba‑Ostria, Daniela Araiza‑Olivera, Natalia Chiquete‑Félix, Sergio Guerrero‑Castillo, Eduardo Rial, Dimitris Georgellis and Salvador Uribe‑Carvajal..........317‑325
- Published as BJ Immediate Publication 11 January 2012, doi:10.1042/BJ20110992
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Volume 442
- PI3K signalling in B- and T-lymphocytes: new developments and therapeutic advances
- Lomon So and David A. Fruman..........465‑481
- Published on the Internet 24 February 2012, doi:10.1042/BJ20112092
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- Allosteric antibody inhibition of human hepsin protease
- Tobias Koschubs, Stefan Dengl, Harald Dürr, Klaus Kaluza, Guy Georges, Christiane Hartl, Stefan Jennewein, Martin Lanzendörfer, Johannes Auer, Alvin Stern, Kuo‑Sen Huang, Kathryn Packman, Ueli Gubler, Dirk Kostrewa, Stefan Ries, Silke Hansen, Ulrich Kohnert, Patrick Cramer and Olaf Mundigl..........483‑494
- Published as BJ Immediate Publication 2 December 2011, doi:10.1042/BJ20111317
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- The chromatin-binding protein HMGN3 stimulates histone acetylation and transcription across the Glyt1 gene
- Gráinne Barkess, Yuri Postnikov, Chrisanne D. Campos, Shivam Mishra, Gokula Mohan, Sakshi Verma, Michael Bustin and Katherine L. West..........495‑505
- Published as BJ Immediate Publication 12 December 2011, doi:10.1042/BJ20111502
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- Macromolecular and small-molecule modulation of intracellular Aβ42 aggregation and associated toxicity
- Sohini Chakrabortee, Yun Liu, Liao Zhang, Helena R. Matthews, Hanrui Zhang, Ni Pan, Chun‑ru Cheng, Shu‑hong Guan, De‑an Guo, Zebo Huang, Yizhi Zheng and Alan Tunnacliffe..........507‑515
- Published as BJ Immediate Publication 9 December 2011, doi:10.1042/BJ20111661
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- Structural determinants for rCNT2 sorting to the plasma membrane of polarized and non-polarized cells
- Itziar Pinilla‑Macua, F. Javier Casado and Marçal Pastor‑Anglada..........517‑525
- Published as BJ Immediate Publication 2 December 2011, doi:10.1042/BJ20110605
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- Solution structure of the Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA
- Yu Qiu, Wen Zhang, Chen Zhao, Yan Wang, Weiwei Wang, Jiahai Zhang, Zhiyong Zhang, Guohong Li, Yunyu Shi, Xiaoming Tu and Jihui Wu..........527‑538
- Published as BJ Immediate Publication 13 December 2011, doi:10.1042/BJ20111885
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Reprogramming of pancreatic exocrine cells towards a beta (β) cell character using Pdx1, Ngn3 and MafA
- Ersin Akinci, Anannya Banga, Lucas V. Greder, James R. Dutton and Jonathan M. W. Slack..........539‑550
- Published as BJ Immediate Publication 9 December 2011, doi:10.1042/BJ20111678
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- A Golgi-localized MATE transporter mediates iron homoeostasis under osmotic stress in Arabidopsis
- Pil Joon Seo, Jungmin Park, Mi‑Jeong Park, Youn‑Sung Kim, Sang‑Gyu Kim, Jae‑Hoon Jung and Chung‑Mo Park..........551‑561
- Published as BJ Immediate Publication 8 December 2011, doi:10.1042/BJ20111311
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A molten globule-to-ordered structure transition of Drosophila melanogaster crammer is required for its ability to inhibit cathepsin
- Tien‑Sheng Tseng, Chao‑Sheng Cheng, Dian‑Jiun Chen, Min‑Fang Shih, Yu‑Nan Liu, Shang‑Te Danny Hsu and Ping‑Chiang Lyu..........563‑572
- Published as BJ Immediate Publication 9 December 2011, doi:10.1042/BJ20111360
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- RCD1–DREB2A interaction in leaf senescence and stress responses in Arabidopsis thaliana
- Julia P. Vainonen, Pinja Jaspers, Michael Wrzaczek, Airi Lamminmäki, Ramesha A. Reddy, Lauri Vaahtera, Mikael Brosché and Jaakko Kangasjärvi..........573‑581
- Published as BJ Immediate Publication 12 December 2011, doi:10.1042/BJ20111739
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- Human-protein-derived peptides for intracellular delivery of biomolecules
- Alexander K. Haas, Daniela Maisel, Juliane Adelmann, Christoffer von Schwerin, Ines Kahnt and Ulrich Brinkmann..........583‑593
- Published as BJ Immediate Publication 13 December 2011, doi:10.1042/BJ20111973
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A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3)
- Stephen J. Fuller, Liam J. McGuffin, Andrew K. Marshall, Alejandro Giraldo, Sampsa Pikkarainen, Angela Clerk and Peter H. Sugden..........595‑610
- Published as BJ Immediate Publication 9 January 2012, doi:10.1042/BJ20112000
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- Targeting Lyn tyrosine kinase through protein fusions encompassing motifs of Cbp (Csk-binding protein) and the SOCS box of SOCS1
- Rhiannon J. Whiting, Christine J. Payne, Jiulia Satiaputra, Nicole Kucera, Theresa W. Qiu, Sevgi Irtegun, Natalie J. Gunn, Neli S. Lavova‑Azmanova, Terrence D. Mulhern and Evan Ingley..........611‑620
- Published as BJ Immediate Publication 24 February 2012, doi:10.1042/BJ20111485
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- Plastoquinone-9 biosynthesis in cyanobacteria differs from that in plants and involves a novel 4-hydroxybenzoate solanesyltransferase
- Radin Sadre, Christian Pfaff and Stephan Buchkremer..........621‑629
- Published as BJ Immediate Publication 14 December 2011, doi:10.1042/BJ20111796
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Inhibition of protein translocation at the endoplasmic reticulum promotes activation of the unfolded protein response
- Craig McKibbin, Alina Mares, Michela Piacenti, Helen Williams, Peristera Roboti, Marjo Puumalainen, Anna C. Callan, Karolina Lesiak‑Mieczkowska, Stig Linder, Hanna Harant, Stephen High, Sabine L. Flitsch, Roger C. Whitehead and Eileithyia Swanton..........639‑648
- Published as BJ Immediate Publication 6 December 2011, doi:10.1042/BJ20111220
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Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells
- Maria N. Navarro, Linda V. Sinclair, Carmen Feijoo‑Carnero, Rosemary Clarke, Sharon A. Matthews and Doreen A. Cantrell..........649‑659
- Published as BJ Immediate Publication 10 January 2012, doi:10.1042/BJ20111700
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- A cohesin–RAD21 interactome
- Anil K. Panigrahi, Nenggang Zhang, Subhendu K. Otta and Debananda Pati..........661‑670
- Published as BJ Immediate Publication 7 December 2011, doi:10.1042/BJ20111745
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- A novel glutaredoxin domain-containing peroxiredoxin ‘All1541’ protects the N2-fixing cyanobacterium Anabaena PCC 7120 from oxidative stress
- Manisha Banerjee, Anand Ballal and Shree K. Apte..........671‑680
- Published as BJ Immediate Publication 8 December 2011, doi:10.1042/BJ20111877
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Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase
- Sébastien Pyr Dit Ruys, Xuemin Wang, Ewan M. Smith, Gaëtan Herinckx, Nusrat Hussain, Mark H. Rider, Didier Vertommen and Christopher G. Proud..........681‑692
- Published as BJ Immediate Publication 4 January 2012, doi:10.1042/BJ20111530
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Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes
- Yu Wu, Nora Steinbergs, Tracy Murray‑Stewart, Laurence J. Marton and Robert A. Casero..........693‑701
- Published as BJ Immediate Publication 2 December 2011, doi:10.1042/BJ20111271
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- Folded functional lipid-poor apolipoprotein A-I obtained by heating of high-density lipoproteins: relevance to high-density lipoprotein biogenesis
- Shobini Jayaraman, Giorgio Cavigiolio and Olga Gursky..........703‑712
- Published as BJ Immediate Publication 8 December 2011, doi:10.1042/BJ20111831
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- Selective reduction of hydroperoxyeicosatetraenoic acids to their hydroxy derivatives by apolipoprotein D: implications for lipid antioxidant activity and Alzheimer's disease
- Surabhi Bhatia, Bianca Knoch, Jenny Wong, Woojin S. Kim, Paul L. Else, Aaron J. Oakley and Brett Garner..........713‑721
- Published as BJ Immediate Publication 12 December 2011, doi:10.1042/BJ20111166
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- IκB kinase β (IKKβ) does not mediate feedback inhibition of the insulin signalling cascade
- Graeme I. Lancaster, Beata Skiba, Christine Yang, Hayley T. Nicholls, Katherine G. Langley, M. H. Stanley Chan, Clinton R. Bruce, Gordon W. Rewcastle, Peter R. Shepherd, Michael Karin and Mark A. Febbraio..........723‑732
- Published as BJ Immediate Publication 14 December 2011, doi:10.1042/BJ20112037
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- 2-Carboxy-D-arabinitol 1-phosphate (CA1P) phosphatase: evidence for a wider role in plant Rubisco regulation
- Paul John Andralojc, Pippa J. Madgwick, Yong Tao, Alfred Keys, Jane L. Ward, Michael H. Beale, Jane E. Loveland, Phil J. Jackson, Antony C. Willis, Steven Gutteridge and Martin A.J. Parry..........733‑742
- Published as BJ Immediate Publication 2 December 2011, doi:10.1042/BJ20111443
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- Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence
- Porkodi Panneerselvam, Laishram Pradeepkumar Singh, Bow Ho, Jianzhu Chen and Jeak Ling Ding..........263‑271
- Published on the Internet 13 February 2012, doi:10.1042/BJ20111653
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- The crystal structure of human UDP-glucose pyrophosphorylase reveals a latch effect that influences enzymatic activity
- Quan Yu and Xiaofeng Zheng..........283‑291
- Published as BJ Immediate Publication 1 December 2011, doi:10.1042/BJ20111598
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- Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways
- Ming‑Cheng Chang, Chi‑An Chen, Pao‑Jen Chen, Ying‑Cheng Chiang, Yu‑Li Chen, Tsui‑Lien Mao, Han‑Wei Lin, Wen‑Hsien Lin Chiang and Wen‑Fang Cheng..........293‑302
- Published as BJ Immediate Publication 14 October 2011, doi:10.1042/BJ20110282
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- Up-regulated miR-17 promotes cell proliferation, tumour growth and cell cycle progression by targeting the RND3 tumour suppressor gene in colorectal carcinoma
- Hesan Luo, Jinjin Zou, Zhongyi Dong, Qin Zeng, Dehua Wu and Li Liu..........311‑321
- Published as BJ Immediate Publication 1 December 2011, doi:10.1042/BJ20111517
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- An aspartate residue in the external vestibule of GLYT2 (glycine transporter 2) controls cation access and transport coupling
- Gonzalo Pérez‑Siles, Enrique Núñez, Antonio Morreale, Esperanza Jiménez, Alejandra Leo‑Macías, Guillermo Pita, Francesca Cherubino, Rachele Sangaletti, Elena Bossi, Ángel R. Ortíz, Carmen Aragón and Beatriz López‑Corcuera..........323‑334
- Published as BJ Immediate Publication 1 December 2011, doi:10.1042/BJ20110247
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- Lactococcus lactis HemW (HemN) is a haem-binding protein with a putative role in haem trafficking
- Helge K. Abicht, Jacobo Martinez, Gunhild Layer, Dieter Jahn and Marc Solioz..........335‑343
- Published as BJ Immediate Publication 5 December 2011, doi:10.1042/BJ20111618
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- Functional mapping of the disparate activities of the yeast moonlighting protein Hal3
- J. Albert Abrie, Asier González, Erick Strauss and Joaquín Ariño..........357‑368
- Published as BJ Immediate Publication 29 November 2011, doi:10.1042/BJ20111466
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- Hydroperoxide and peroxynitrite reductase activity of poplar thioredoxin-dependent glutathione peroxidase 5: kinetics, catalytic mechanism and oxidative inactivation
- Benjamin Selles, Martin Hugo, Madia Trujillo, Vaibhav Srivastava, Gunnar Wingsle, Jean‑Pierre Jacquot, Rafael Radi and Nicolas Rouhier..........369‑380
- Published as BJ Immediate Publication 29 November 2011, doi:10.1042/BJ20111378
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- Membrane integration of a mitochondrial signal-anchored protein does not require additional proteinaceous factors
- Elisa Merklinger, Yana Gofman, Alexej Kedrov, Arnold J. M. Driessen, Nir Ben‑Tal, Yechiel Shai and Doron Rapaport..........381‑389
- Published as BJ Immediate Publication 5 December 2011, doi:10.1042/BJ20111363
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- Inactivation of ceramide transfer protein during pro-apoptotic stress by Golgi disassembly and caspase cleavage
- Suchismita Chandran and Carolyn E. Machamer..........391‑401
- Published as BJ Immediate Publication 1 December 2011, doi:10.1042/BJ20111461
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- Inhibition of glutaminyl cyclase attenuates cell migration modulated by monocyte chemoattractant proteins
- Yi‑Ling Chen, Kai‑Fa Huang, Wen‑Chih Kuo, Yan‑Chung Lo, Yu‑May Lee and Andrew H.‑J. Wang..........403‑412
- Published as BJ Immediate Publication 8 November 2011, doi:10.1042/BJ20110535
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- MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer's disease-related mutants of amyloid β precursor protein and presenilins
- Nobuyuki Tachi, Yuichi Hashimoto and Masaaki Matsuoka..........413‑422
- Published as BJ Immediate Publication 24 November 2011, doi:10.1042/BJ20100993
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- Oxidation of Met1606 in von Willebrand factor is a risk factor for thrombotic and septic complications in chronic renal failure
- Vincenzo De Filippis, Stefano Lancellotti, Fabio Maset, Barbara Spolaore, Nicola Pozzi, Giovanni Gambaro, Laura Oggianu, Lorenzo A. Calò and Raimondo De Cristofaro..........423‑432
- Published as BJ Immediate Publication 18 November 2011, doi:10.1042/BJ20111798
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- Secreted CXCL12 (SDF-1) forms dimers under physiological conditions
- Paramita Ray, Sarah A. Lewin, Laura Anne Mihalko, Sasha‑Cai Lesher‑Perez, Shuichi Takayama, Kathryn E. Luker and Gary D. Luker..........433‑442
- Published as BJ Immediate Publication 6 December 2011, doi:10.1042/BJ20111341
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- Interfacial water molecules in SH3 interactions: a revised paradigm for polyproline recognition
- Jose M. Martin‑Garcia, Javier Ruiz‑Sanz and Irene Luque..........443‑451
- Published as BJ Immediate Publication 24 November 2011, doi:10.1042/BJ20111089
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- New insights into the structure of the reaction centre from Blastochloris viridis: evolution in the laboratory
- Aleksander W. Roszak, Vladimíra Moulisová, Adhie D. P. Reksodipuro, Alastair T. Gardiner, Ritsuko Fujii, Hideki Hashimoto, Neil W. Isaacs and Richard J. Cogdell..........27‑37
- Published as BJ Immediate Publication 4 November 2011, doi:10.1042/BJ20111540
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- Palmitoylation and trafficking of GAD65 are impaired in a cellular model of Huntington's disease
- Daniel B. Rush, Rebecca T. Leon, Mark H. McCollum, Ryan W. Treu and Jianning Wei..........39‑48
- Published as BJ Immediate Publication 21 November 2011, doi:10.1042/BJ20110679
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- Identification of two independent nucleosome-binding domains in the transcriptional co-activator SPBP
- Sagar Darvekar, Sylvia Sagen Johnsen, Agnete Bratsberg Eriksen, Terje Johansen and Eva Sjøttem..........65‑75
- Published as BJ Immediate Publication 14 November 2011, doi:10.1042/BJ20111230
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Staphylococcus aureus DinG, a helicase that has evolved into a nuclease
- Anne‑Marie McRobbie, Bjoern Meyer, Christophe Rouillon, Biljana Petrovic‑Stojanovska, Huanting Liu and Malcolm F. White..........77‑84
- Published as BJ Immediate Publication 14 December 2011, doi:10.1042/BJ20111903
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- EscI: a crucial component of the type III secretion system forms the inner rod structure in enteropathogenic Escherichia coli
- Neta Sal‑Man, Wanyin Deng and B. Brett Finlay..........119‑125
- Published as BJ Immediate Publication 17 November 2011, doi:10.1042/BJ20111620
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- Induction of group IVC phospholipase A2 in allergic asthma: transcriptional regulation by TNFα in bronchoepithelial cells
- Justin S. Bickford, Kimberly J. Newsom, John‑David Herlihy, Christian Mueller, Benjamin Keeler, Xiaolei Qiu, Jewell N. Walters, Nan Su, Shannon M. Wallet, Terence R. Flotte and Harry S. Nick..........127‑137
- Published as BJ Immediate Publication 15 November 2011, doi:10.1042/BJ20111269
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- CaMKII-γ mediates phosphorylation of BAD at Ser170 to regulate cytokine-dependent survival and proliferation
- Payman Hojabrpour, Ivan Waissbluth, Mazyar Ghaffari, Michael E. Cox and Vincent Duronio..........139‑149
- Published as BJ Immediate Publication 22 November 2011, doi:10.1042/BJ20111256
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Effects of acutely inhibiting PI3K isoforms and mTOR on regulation of glucose metabolism in vivo
- Greg C. Smith, Wee Kiat Ong, Gordon W. Rewcastle, Jackie D. Kendall, Weiping Han and Peter R. Shepherd..........161‑169
- Published as BJ Immediate Publication 5 December 2011, doi:10.1042/BJ20111913
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- Identification of 4-hydroxy-2-nonenal–histidine adducts that serve as ligands for human lectin-like oxidized LDL receptor-1
- Miyuki Kumano‑Kuramochi, Yuuki Shimozu, Chika Wakita, Mayumi Ohnishi‑Kameyama, Takahiro Shibata, Shigeru Matsunaga, Yuko Takano‑Ishikawa, Jun Watanabe, Masao Goto, Qiuhong Xie, Shiro Komba, Koji Uchida and Sachiko Machida..........171‑180
- Published as BJ Immediate Publication 11 November 2011, doi:10.1042/BJ20111029
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- A preliminary characterization of the cytosolic glutathione transferase proteome from Drosophila melanogaster
- Chonticha Saisawang, Jantana Wongsantichon and Albert J. Ketterman..........181‑190
- Published as BJ Immediate Publication 15 November 2011, doi:10.1042/BJ20111747
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- Ornithine decarboxylase mRNA is stabilized in an mTORC1-dependent manner in Ras-transformed cells
- Sofia Origanti, Shannon L. Nowotarski, Theresa D. Carr, Suzanne Sass‑Kuhn, Lan Xiao, Jian‑Ying Wang and Lisa M. Shantz..........199‑207
- Published as BJ Immediate Publication 10 November 2011, doi:10.1042/BJ20111464
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- Recruitment of the endosomal WASH complex is mediated by the extended ‘tail’ of Fam21 binding to the retromer protein Vps35
- Michael E. Harbour, Sophia Y. Breusegem and Matthew N. J. Seaman..........209‑220
- Published as BJ Immediate Publication 9 November 2011, doi:10.1042/BJ20111761
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- Ellagic acid, a new antiglycating agent: its inhibition of Nϵ-(carboxymethyl)lysine
- Puppala Muthenna, Chandrasekhar Akileshwari and G. Bhanuprakash Reddy..........221‑230
- Published as BJ Immediate Publication 8 November 2011, doi:10.1042/BJ20110846
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Volume 441
The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in co-ordinating its activities
- Matthew Brook, Lora McCracken, James P. Reddington, Zhi‑Liang Lu, Nicholas A. Morrice and Nicola K. Gray..........803‑812
- Published as BJ Immediate Publication 18 October 2011, doi:10.1042/BJ20111474
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- Identification of persulfide-binding and disulfide-forming cysteine residues in the NifS-like domain of the molybdenum cofactor sulfurase ABA3 by cysteine-scanning mutagenesis
- Markus Lehrke, Steffen Rump, Torsten Heidenreich, Josef Wissing, Ralf R. Mendel and Florian Bittner..........823‑832
- Published as BJ Immediate Publication 17 October 2011, doi:10.1042/BJ20111170
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- The full-length Streptococcus pneumoniae major pilin RrgB crystallizes in a fibre-like structure, which presents the D1 isopeptide bond and provides details on the mechanism of pilus polymerization
- Lamya El Mortaji, Carlos Contreras‑Martel, Monica Moschioni, Ilaria Ferlenghi, Clothilde Manzano, Thierry Vernet, Andrea Dessen and Anne Marie Di Guilmi..........833‑841
- Published as BJ Immediate Publication 21 October 2011, doi:10.1042/BJ20111397
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- α-Haemoglobin regulates sympathoadrenal cell metabolism to maintain a catecholaminergic phenotype
- María T. Marcos‑Almaraz, José A. Rodríguez‑Gómez, José López‑Barneo and Alberto Pascual..........843‑850
- Published as BJ Immediate Publication 8 November 2011, doi:10.1042/BJ20111640
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- Large T-antigen up-regulates Kv4.3 K+ channels through Sp1, and Kv4.3 K+ channels contribute to cell apoptosis and necrosis through activation of calcium/calmodulin-dependent protein kinase II
- Qi Li, Ying Zhang, Yue Sheng, Rong Huo, Bo Sun, Xue Teng, Na Li, Jiu‑Xin Zhu, Bao‑Feng Yang and De‑Li Dong..........859‑867
- Published as BJ Immediate Publication 25 October 2011, doi:10.1042/BJ20111604
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- Detection of Rho GEF and GAP activity through a sensitive split luciferase assay system
- Erik L. Anderson and Michael J. Hamann..........869‑879
- Published as BJ Immediate Publication 17 October 2011, doi:10.1042/BJ20111111
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- Abi-1-bridged tyrosine phosphorylation of VASP by Abelson kinase impairs association of VASP to focal adhesions and regulates leukaemic cell adhesion
- Masahiro Maruoka, Mizuho Sato, Yunfeng Yuan, Masayoshi Ichiba, Ryosuke Fujii, Takuya Ogawa, Norihiro Ishida‑Kitagawa, Tatsuo Takeya and Naoki Watanabe..........889‑899
- Published as BJ Immediate Publication 20 October 2011, doi:10.1042/BJ20110951
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- Platelet-derived growth factor-C (PDGF-C) activation by serine proteases: implications for breast cancer progression
- Newton J. Hurst, Abdo J. Najy, Carolyn V. Ustach, Lisa Movilla and Hyeong‑Reh Choi Kim..........909‑918
- Published as BJ Immediate Publication 28 October 2011, doi:10.1042/BJ20111020
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- BRCA1-mediated repression of mutagenic end-joining of DNA double-strand breaks requires complex formation with BACH1
- Lisa Dohrn, Daniela Salles, Simone Y. Siehler, Julia Kaufmann and Lisa Wiesmüller..........919‑926
- Published as BJ Immediate Publication 28 October 2011, doi:10.1042/BJ20110314
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- Ubiquitin-specific protease 4 (USP4) targets TRAF2 and TRAF6 for deubiquitination and inhibits TNFα-induced cancer cell migration
- Ning Xiao, Hui Li, Jian Luo, Rui Wang, Haiquan Chen, Jiquan Chen and Ping Wang..........979‑986
- Published as BJ Immediate Publication 27 October 2011, doi:10.1042/BJ20111358
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Re-examination of the dimerization state of leucine-rich repeat kinase 2: predominance of the monomeric form
- Genta Ito and Takeshi Iwatsubo..........987‑994
- Published as BJ Immediate Publication 2 November 2011, doi:10.1042/BJ20111215
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- The adaptor protein 14-3-3 binds to the calcium-sensing receptor and attenuates receptor-mediated Rho kinase signalling
- Ajanthy Arulpragasam, Aaron L. Magno, Evan Ingley, Suzanne J. Brown, Arthur D. Conigrave, Thomas Ratajczak and Bryan K. Ward..........995‑1006
- Published as BJ Immediate Publication 19 October 2011, doi:10.1042/BJ20111277
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Homo- and hetero-dimeric architecture of the human liver Na+-dependent taurocholate co-transporting protein
- Ingrid T. G. W. Bijsmans, Rianne A. M. Bouwmeester, Joachim Geyer, Klaas Nico Faber and Stan F. J. van de Graaf..........1007‑1015
- Published as BJ Immediate Publication 26 October 2011, doi:10.1042/BJ20111234
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni2+ and Zn2+ reveals a role for the disordered C-terminal arm in metal trafficking
- Katarzyna Banaszak, Vlad Martin‑Diaconescu, Matteo Bellucci, Barbara Zambelli, Wojciech Rypniewski, Michael J. Maroney and Stefano Ciurli..........1017‑1026
- Published as BJ Immediate Publication 20 October 2011, doi:10.1042/BJ20111659
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Visualization of co-localization in Aβ42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death
- Violetta Soura, Maris Stewart‑Parker, Thomas L. Williams, Arjuna Ratnayaka, Joe Atherton, Kirsti Gorringe, Jack Tuffin, Elisabeth Darwent, Roma Rambaran, William Klein, Pascale Lacor, Kevin Staras, Julian Thorpe and Louise C. Serpell..........579‑590
- Published as BJ Immediate Publication 29 September 2011, doi:10.1042/BJ20110749
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Structure of the mRNA splicing complex component Cwc2: insights into RNA recognition
- Peilong Lu, Guifeng Lu, Chuangye Yan, Li Wang, Wenqi Li and Ping Yin..........591‑597
- Published as BJ Immediate Publication 30 September 2011, doi:10.1042/BJ20111385
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Biochemical insight into physiological effects of H2S: reaction with peroxynitrite and formation of a new nitric oxide donor, sulfinyl nitrite
- Milos R. Filipovic, Jan Miljkovic, Andrea Allgäuer, Ricardo Chaurio, Tatyana Shubina, Martin Herrmann and Ivana Ivanovic‑Burmazovic..........609‑621
- Published as BJ Immediate Publication 28 September 2011, doi:10.1042/BJ20111389
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Metallothioneins protect cytosolic creatine kinases against stress induced by nitrogen-based oxidants
- Zhe Chen, Jie Li, Tong‑Jin Zhao, Xu‑Hui Li, Fan‑Guo Meng, Hang Mu, Yong‑Bin Yan and Hai‑Meng Zhou..........623‑632
- Published as BJ Immediate Publication 3 October 2011, doi:10.1042/BJ20111565
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
ADP-ribose polymers localized on Ctcf–Parp1–Dnmt1 complex prevent methylation of Ctcf target sites
- Michele Zampieri, Tiziana Guastafierro, Roberta Calabrese, Fabio Ciccarone, Maria G. Bacalini, Anna Reale, Mariagrazia Perilli, Claudio Passananti and Paola Caiafa..........645‑652
- Published as BJ Immediate Publication 11 October 2011, doi:10.1042/BJ20111417
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Hypoxia-inducible factor-1 (HIF-1) promotes LDL and VLDL uptake through inducing VLDLR under hypoxia
- Guo‑Min Shen, Ying‑Ze Zhao, Ming‑Tai Chen, Feng‑Lin Zhang, Xiao‑Ling Liu, Yi Wang, Chang‑Zheng Liu, Jia Yu and Jun‑Wu Zhang..........675‑683
- Published as BJ Immediate Publication 4 October 2011, doi:10.1042/BJ20111377
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Chondroitin 4-O-sulfotransferase-2 regulates the number of chondroitin sulfate chains initiated by chondroitin N-acetylgalactosaminyltransferase-1
- Tomomi Izumikawa, Toshiyasu Koike and Hiroshi Kitagawa..........697‑705
- Published as BJ Immediate Publication 27 September 2011, doi:10.1042/BJ20111472
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Regulation by mitochondrial superoxide and NADPH oxidase of cellular formation of nitrated cyclic GMP: potential implications for ROS signalling
- Khandaker Ahtesham Ahmed, Tomohiro Sawa, Hideshi Ihara, Shingo Kasamatsu, Jun Yoshitake, Md. Mizanur Rahaman, Tatsuya Okamoto, Shigemoto Fujii and Takaaki Akaike..........719‑730
- Published as BJ Immediate Publication 4 October 2011, doi:10.1042/BJ20111130
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- SRP-35, a newly identified protein of the skeletal muscle sarcoplasmic reticulum, is a retinol dehydrogenase
- Susan Treves, Raphael Thurnheer, Barbara Mosca, Mirko Vukcevic, Leda Bergamelli, Rebecca Voltan, Vitus Oberhauser, Michel Ronjat, Laszlo Csernoch, Peter Szentesi and Francesco Zorzato..........731‑741
- Published as BJ Immediate Publication 14 October 2011, doi:10.1042/BJ20111457
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Glu106 in the Orai1 pore contributes to fast Ca2+-dependent inactivation and pH dependence of Ca2+ release-activated Ca2+ (CRAC) current
- Nathan R. Scrimgeour, David P. Wilson and Grigori Y. Rychkov..........743‑753
- Published as BJ Immediate Publication 3 October 2011, doi:10.1042/BJ20110558
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease
- Rohan D. Teasdale and Brett M. Collins..........39‑59
- Published on the Internet 14 December 2011, doi:10.1042/BJ20111226
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Multimedia
- Data-driven modelling of receptor tyrosine kinase signalling networks quantifies receptor-specific potencies of PI3K- and Ras-dependent ERK activation
- Murat Cirit and Jason M. Haugh..........77‑85
- Published as BJ Immediate Publication 26 September 2011, doi:10.1042/BJ20110833
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Absence of ABCG2-mediated mucosal detoxification in patients with active inflammatory bowel disease is due to impeded protein folding
- J. Jasper Deuring, Colin de Haar, Chantal L. Koelewijn, Ernst J. Kuipers, Maikel P. Peppelenbosch and C. Janneke van der Woude..........87‑93
- Published as BJ Immediate Publication 25 August 2011, doi:10.1042/BJ20111281
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Multimedia
- Dissecting structure–function–stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168
- Camila R. Santos, Joice H. Paiva, Maurício L. Sforça, Jorge L. Neves, Rodrigo Z. Navarro, Júnio Cota, Patrícia K. Akao, Zaira B. Hoffmam, Andréia N. Meza, Juliana H. Smetana, Maria L. Nogueira, Igor Polikarpov, José Xavier‑Neto, Fábio M. Squina, Richard J. Ward, Roberto Ruller, Ana C. Zeri and Mário T. Murakami..........95‑104
- Published as BJ Immediate Publication 1 September 2011, doi:10.1042/BJ20110869
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Determinants of the enzymatic activity and the subcellular localization of aspartate N-acetyltransferase
- Gaëlle Tahay, Elsa Wiame, Donatienne Tyteca, Pierre J. Courtoy and Emile Van Schaftingen..........105‑112
- Published as BJ Immediate Publication 21 September 2011, doi:10.1042/BJ20111179
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4
- Xi Wang, Likun Wang, Xi'e Wang, Fei Sun and Chih‑chen Wang..........113‑118
- Published as BJ Immediate Publication 15 September 2011, doi:10.1042/BJ20110380
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response
- Jing‑Wen Shih, Wei‑Ting Wang, Tsung‑Yuan Tsai, Chu‑Yun Kuo, Hao‑Kang Li and Yan‑Hwa Wu Lee..........119‑129
- Published as BJ Immediate Publication 1 September 2011, doi:10.1042/BJ20110739
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism
- Silvia Garavaglia, Santina Bruzzone, Camilla Cassani, Laura Canella, Gianna Allegrone, Laura Sturla, Elena Mannino, Enrico Millo, Antonio De Flora and Menico Rizzi..........131‑141
- Published as BJ Immediate Publication 20 September 2011, doi:10.1042/BJ20111263
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Multimedia
- Length of the active-site crossover loop defines the substrate specificity of ubiquitin C-terminal hydrolases for ubiquitin chains
- Zi‑Ren Zhou, Yu‑Hang Zhang, Shuai Liu, Ai‑Xin Song and Hong‑Yu Hu..........143‑149
- Published as BJ Immediate Publication 19 August 2011, doi:10.1042/BJ20110699
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Insights into subtle conformational differences in the substrate-binding loop of fungal 17β-hydroxysteroid dehydrogenase: a combined structural and kinetic approach
- Alberto Cassetta, Ivet Krastanova, Katja Kristan, Mojca Brunskole Švegelj, Doriano Lamba, Tea Lanišnik Rižner and Jure Stojan..........151‑160
- Published as BJ Immediate Publication 19 September 2011, doi:10.1042/BJ20110567
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- A novel class of PTEN protein in Arabidopsis displays unusual phosphoinositide phosphatase activity and efficiently binds phosphatidic acid
- Anne Pribat, Rodnay Sormani, Mathieu Rousseau‑Gueutin, Magdalena M. Julkowska, Christa Testerink, Jerôme Joubès, Michel Castroviejo, Michel Laguerre, Christian Meyer, Véronique Germain and Christophe Rothan..........161‑171
- Published as BJ Immediate Publication 24 August 2011, doi:10.1042/BJ20110776
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2
- Christian Krintel, Karla Frydenvang, Lars Olsen, Maria T. Kristensen, Oriol de Barrios, Peter Naur, Pierre Francotte, Bernard Pirotte, Michael Gajhede and Jette S. Kastrup..........173‑178
- Published as BJ Immediate Publication 7 September 2011, doi:10.1042/BJ20111221
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Revealing the structural origin of the redox-Bohr effect: the first solution structure of a cytochrome from Geobacter sulfurreducens
- Leonor Morgado, Vítor B. Paixão, Marianne Schiffer, P. Raj Pokkuluri, Marta Bruix and Carlos A. Salgueiro..........179‑187
- Published as BJ Immediate Publication 24 August 2011, doi:10.1042/BJ20111103
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt
- Ruomin Di, Xiangqi Wu, Zai Chang, Xia Zhao, Qiuting Feng, Shuangshuang Lu, Qing Luan, Brian A. Hemmings, Xinli Li and Zhongzhou Yang..........199‑207
- Published as BJ Immediate Publication 9 September 2011, doi:10.1042/BJ20110033
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- A global survey of CRM1-dependent nuclear export sequences in the human deubiquitinase family
- Iraia García‑Santisteban, Sonia Bañuelos and Jose A. Rodríguez..........209‑217
- Published as BJ Immediate Publication 2 September 2011, doi:10.1042/BJ20111300
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Adaptive evolution of drug targets in producer and non-producer organisms
- Bjarne G. Hansen, Xin E. Sun, Hans J. Genee, Christian S. Kaas, Jakob B. Nielsen, Uffe H. Mortensen, Jens C. Frisvad and Lizbeth Hedstrom..........219‑226
- Published as BJ Immediate Publication 15 September 2011, doi:10.1042/BJ20111278
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Targeted polyubiquitylation of RASSF1C by the Mule and SCFβ-TrCP ligases in response to DNA damage
- Xin Zhou, Ting‑Ting Li, Xu Feng, Esther Hsiang, Yue Xiong, Kun‑Liang Guan and Qun‑Ying Lei..........227‑236
- Published as BJ Immediate Publication 12 September 2011, doi:10.1042/BJ20111500
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Translation of a minigene in the 5′ leader sequence of the enterohaemorrhagic Escherichia coli LEE1 transcription unit affects expression of the neighbouring downstream gene
- Md. Shahidul Islam, Robert K. Shaw, Gad Frankel, Mark J. Pallen and Stephen J. W. Busby..........247‑253
- Published as BJ Immediate Publication 6 October 2011, doi:10.1042/BJ20110912
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice
- Paul J. Meakin, Alex J. Harper, D. Lee Hamilton, Jennifer Gallagher, Alison D. McNeilly, Laura A. Burgess, Lobke M. Vaanholt, Kirsten A. Bannon, Judy Latcham, Ishrut Hussain, John R. Speakman, David R. Howlett and Michael L.J. Ashford..........285‑296
- Published as BJ Immediate Publication 31 August 2011, doi:10.1042/BJ20110512
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- BAG-1 diversely affects steroid receptor activity
- Regina T. Knapp, Andrea Steiner, Ulrike Schmidt, Kathrin Hafner, Florian Holsboer and Theo Rein..........297‑303
- Published as BJ Immediate Publication 15 September 2011, doi:10.1042/BJ20111456
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
Domain assembly of NAADP-gated two-pore channels
- Dev Churamani, Robert Hooper, Eugen Brailoiu and Sandip Patel..........317‑323
- Published as BJ Immediate Publication 12 October 2011, doi:10.1042/BJ20111617
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SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation
- Jacob O. Thastrup, Fatema H. Rafiqi, Alberto C. Vitari, Eulalia Pozo‑Guisado, Maria Deak, Youcef Mehellou and Dario R. Alessi..........325‑337
- Published as BJ Immediate Publication 28 October 2011, doi:10.1042/BJ20111879
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- Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system
- Eddy T. H. Goh, J. Simon C. Arthur, Peter C. F. Cheung, Shizuo Akira, Rachel Toth and Philip Cohen..........339‑346
- Published as BJ Immediate Publication 18 October 2011, doi:10.1042/BJ20111415
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- Aldehyde stress and up-regulation of Nrf2-mediated antioxidant systems accompany functional adaptations in cardiac mitochondria from mice fed n−3 polyunsaturated fatty acids
- Ethan J. Anderson, Kathleen Thayne, Mitchel Harris, Kristen Carraway and Saame Raza Shaikh..........359‑366
- Published as BJ Immediate Publication 31 August 2011, doi:10.1042/BJ20110626
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- PTEN interacts with metal-responsive transcription factor 1 and stimulates its transcriptional activity
- Meng‑Chieh Lin, Ya‑Chuan Liu, Ming F. Tam, Yu‑Ju Lu, Ya‑Ting Hsieh and Lih‑Yuan Lin..........367‑377
- Published as BJ Immediate Publication 1 September 2011, doi:10.1042/BJ20111257
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- Thr90 phosphorylation of Hsp90α by protein kinase A regulates its chaperone machinery
- Xiaofeng Wang, Xin‑an Lu, Xiaomin Song, Wei Zhuo, Lin Jia, Yushan Jiang and Yongzhang Luo..........387‑397
- Published as BJ Immediate Publication 15 September 2011, doi:10.1042/BJ20110855
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Phospholipase D1 mediates bFGF-induced Bcl-2 expression leading to neurite outgrowth in H19-7 cells
- Sung Nyo Yoon, Kang Sik Kim, Ju Hwan Cho, Weina Ma, Hye‑Jin Choi, Sung‑Joon Kwon and Joong‑Soo Han..........407‑416
- Published as BJ Immediate Publication 14 September 2011, doi:10.1042/BJ20110302
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Inhibition of polyglutamine-mediated proteotoxicity by Astragalus membranaceus polysaccharide through the DAF-16/FOXO transcription factor in Caenorhabditis elegans
- Hanrui Zhang, Ni Pan, Siqin Xiong, Shenglong Zou, Haifeng Li, Lingyun Xiao, Zhijian Cao, Alan Tunnacliffe and Zebo Huang..........417‑424
- Published as BJ Immediate Publication 5 September 2011, doi:10.1042/BJ20110621
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Identification of novel small molecules that elevate Klotho expression
- Gwendalyn D. King, CiDi Chen, Mickey M. Huang, Ella Zeldich, Patricia L. Brazee, Eli R. Schuman, Maxime Robin, Gregory D. Cuny, Marcie A. Glicksman and Carmela R. Abraham..........453‑461
- Published as BJ Immediate Publication 22 September 2011, doi:10.1042/BJ20101909
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Directed evolution of a temperature-, peroxide- and alkaline pH-tolerant versatile peroxidase
- Eva Garcia‑Ruiz, David Gonzalez‑Perez, Francisco J. Ruiz‑Dueñas, Angel T. Martínez and Miguel Alcalde..........487‑498
- Published as BJ Immediate Publication 7 October 2011, doi:10.1042/BJ20111199
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Connective tissue growth factor antagonizes transforming growth factor-β1/Smad signalling in renal mesangial cells
- Helen C. O'Donovan, Fionnuala Hickey, Derek P. Brazil, David H. Kavanagh, Noelynn Oliver, Finian Martin, Catherine Godson and John Crean..........499‑510
- Published as BJ Immediate Publication 26 August 2011, doi:10.1042/BJ20110910
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Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Characterization of a novel peripheral pro-lipolytic mechanism in mice: role of VGF-derived peptide TLQP-21
- Roberta Possenti, Giampiero Muccioli, Pamela Petrocchi, Cheryl Cero, Aderville Cabassi, Lucy Vulchanova, Maureen S. Riedl, Monia Manieri, Andrea Frontini, Antonio Giordano, Saverio Cinti, Paolo Govoni, Gallia Graiani, Federico Quaini, Corrado Ghè, Elena Bresciani, Ilaria Bulgarelli, Antonio Torsello, Vittorio Locatelli, Valentina Sanghez, Bjarne D. Larsen, Jorgen S. Petersen, Paola Palanza, Stefano Parmigiani, Anna Moles, Andrea Levi and Alessandro Bartolomucci..........511‑522
- Published as BJ Immediate Publication 31 August 2011, doi:10.1042/BJ20111165
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Online data published in 2011