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Latest Immediate Publications in Biochemical Journal

as at 29 November 2014

What are Biochemical Journal Immediate Publications and how should they be cited?


28 November 2014

Transmembrane Oligomeric form of Vibrio cholerae Cytolysin Triggers TLR2/TLR6-dependent Pro-inflammatory Responses in Monocytes and Macrophages
Barkha Khilwani, Arunika Mukhopadhaya and Kausik Chattopadhyay


A directed-overflow and damage-control N-glycosidase in riboflavin biosynthesis
Océane Frelin, Lili Huang, Ghulam Hasnain, James G Jeffryes, Michael J Ziemak, James R Rocca, Bing Wang, Jennifer Rice, Sanja Roje, Svetlana N Yurgel, Jesse F. Gregory, Arthur S Edison, Christopher S Henry, Valerie de Crecy-Lagard and Andrew D Hanson


Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation-contraction coupling supramolecular complex
Rubén J Lopez, Barbara Mosca, Susan Treves, Marcin Maj, Leda Bergamelli, Juan C Calderon, C Florian Bentzinger, Klaas Romanino, Michael N. Hall, Markus A. Rüegg, Osvaldo Delbono, Carlo Caputo and Francesco Zorzato


27 November 2014

HBx induces the proliferation of hepatocellular carcinoma cells via AP1 overexpressed by ER stress
Hyun Kook Cho, So Young Kim, Yi Yi Kyaw, Aye Aye Win, Seung-Hoi Koo, Hyeong-Hoe Kim and JaeHun Cheong


25 November 2014

Bombyx mori prothoracicostatic peptide receptor is allosterically activated via a Gαi/o protein-biased signaling cascade by Drosophila sex peptide
Xiaobai He, Jiashu Zang, Huipeng Yang, Haishan Huang, Ying Shi, Chenggang Zhu and Naiming Zhou


Andrographolide activates the canonical Wnt signalling pathway by a mechanism that implicates the non-ATP competitive inhibition of GSK-3β: Auto regulation of GSK-3β in vivo
Cheril Tapia-Rojas, Andreas Schüller, Carolina B. Lindsay, Roxana C. Ureta, Cristóbal Mejías-Reyes, Juan Hancke, Francisco Melo and Nibaldo C. Inestrosa


Effects of N-glycosylation on hyperpolarization-activated cyclic nucleotide-gated (HCN) channels
Mo Li, Lige Tonggu, Lan Tang and Liguo Wang


MiR-98 delays skeletal muscle differentiation by downregulating E2F5
Jeremie Kropp, Cindy Degerny, Nadezda Morozova, Julien Pontis, Annick Harel-bellan and Anna Polesskaya


24 November 2014

Steatosis inhibits liver cell store-operated Ca2+ entry and reduces ER Ca2+ through a protein kinase C dependent mechanism
Claire H Wilson, Eunus S Ali, Nathan Scrimgeour, Alyce M Martin, Jin Hua, George A Tallis, Grigori Y Rychkov and Greg J Barritt


The eukaryotic elongation factor eEF1A1 interacts with SAMHD1
Catherine Morrissey, David Schwefel, Valerie Ennis-Adeniran, Ian A Taylor, Yanick J Crow and Michelle Webb


Inositol pyrophosphates regulate RNA polymerase I-mediated rRNA transcription in Saccharomyces cerevisiae
Swarna Gowri Thota, C.p. Unnikannan, Sitalakshmi R. Thampatty, R. Manorama and Rashna Bhandari


The dimeric crystal structure of the human fertility lipocalin glycodelin reveals a protein scaffold for the presentation of complex glycans
André Schiefner, Fabian Rodewald, Irmgard Neumaier and Arne Skerra


21 November 2014

Ubiquitination profiling identifies sensitivity factors for IAP antagonist treatment
Eugene Varfolomeev, Anita Izrael-Tomasevic, Kebing Yu, Daisy Bustos, Tatiana Goncharov, Lisa D Belmont, Alexandre Masselot, Corey E Bakalarski, Donald S Kirkpatrick and Domagoj Vucic


19 November 2014

nhr-176 regulates cyp-35d1 to control hydroxylation-dependent metabolism of thiabendazole in C. elegans
Laura Megan Jones, Anthony J Flemming and Peter Edward Urwin


A quantitative proteomics-based signature of platinum sensitivity in ovarian cancer cell lines
Gaofeng Fan, Kazimierz O. Wrzeszczynski, Cexiong Fu, Gang Su, Darryl J Pappin, Robert Lucito and Nicholas K Tonks


14 November 2014

Fe65 Ser228 is phosphorylated by ATM/ATR and inhibits Fe65–APP-mediated gene transcription
Paul A Jowsey and Peter G Blain


13 November 2014

Plasmodium falciparum mitochondria import tRNAs along with ­­­­an active phenylalanyl-tRNA synthetase­­­­
Arvind Sharma and Amit Sharma


12 November 2014

Structure-Dynamic Determinants Governing a Mode of Regulatory Response and Propagation of Allosteric Signal in Splice Variants of Na+/Ca2+ Exchange (NCX) Proteins
Moshe Giladi, Su Youn Lee, Reuben Hiller, Ka Young Chung and Daniel Khananshvili


11 November 2014

Characterization of excitation–contraction coupling components in human extraocular muscles
Marijana Sekulic-Jablanovic, Anja Palmowski-Wolfe, Francesco Zorzato and Susan Treves


C/EBP homologous protein (CHOP) contributes to hepatocyte death via the promotion of ERO1α signaling in acute liver failure
Jianhua Rao, Chuangyong Zhang, Ping Wang, Ling Lu, Xiaofeng Qian, Jianjie Qin, Xiongxiong Pan, Guoqiang Li, Xuehao Wang and Feng Zhang


Epithelial MUC1 promotes cell migration, reduces apoptosis and affects levels of mucosal modulators during acetylsalicylic acid (aspirin) -induced gastropathy
Debashish Banerjee, Harvey Robert Fernandez, Pradeep Bhatu Patil, Pushpa Premaratne, Marianne Quiding-Järbrink and Sara Katarina Lindén


7 November 2014

New aspects of the structure and mode of action of the human cathelicidin LL-37 revealed by the intrinsic probe p-cyanophenylalanine
Daniela Xhindoli, Francesca Morgera, Ursula Zinth, Roberto Rizzo, Sabrina Pacor and Alessandro Tossi


Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability
Colin J Henderson, Lesley A McLaughlin, Maria Osuna-Cabello, Malcolm Taylor, Ian Gilbert, Aileen W McLaren and C Roland Wolf


Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium
Geetha Samak, Kamaljit K Chaudhry, Ruchika Gangwar, Damodaran Narayanan, Jonathan H Jaggar and Radha Krishna Rao


Gremlin1 preferentially binds to Bone Morphogenetic Protein-2 (BMP-2) and BMP-4 over BMP-7
Rachel H Church, Arjun Krishnakumar, Annika Urbanek, Stefan Geschwindner, Julie Meneely, Alessandro Bianchi, Barbro Basta, Sean Monaghan, Christopher Elliott, Maria Stromstedt, Neil Ferguson, Finian Martin and Derek P Brazil


6 November 2014

Synthetic DAF-12 modulators with potential use in controlling the nematode life cycle
Maria Virginia Dansey, Lautaro Damian Alvarez, Gisela Samaja, Daiana S. Escudero, Adriana Silvia Veleiro, Adali Pecci, Olga Alejandra Castro and Gerardo Burton


5 November 2014

The role of Ca2+ influx in endocytic vacuole formation in pancreatic acinar cells
Svetlana Voronina, David Collier, Michael Chvanov, Ben Middlehurst, Alison J Beckett, Ian A. Prior, David N Criddle, Malcolm Begg, Katsuhiko Mikoshiba, Robert Sutton and Alexei V Tepikin


Identification of Leishmania donovani peroxin 14 residues required for binding the peroxin 5 receptor proteins
Hamed Hojjat and Armando Jardim


4 November 2014

AP2 suppresses osteoblast differentiation and mineralization through down-regulation of Frizzled-1
Shibing Yu, Laura M Yerges-Armstrong, Yanxia Chu, Joseph M Zmuda and Yingze Zhang


The structural basis of DNA binding by the single-stranded DNA-binding protein from Sulfolobus solfataricus
Roland Gamsjaeger, Ruvini Kariawasam, Adrian X Gimenez, Christine Touma, Elysse McIlwain, Ray E Bernardo, Nicholas E Shepherd, Sandro F Ataide, Qihan Dong, Derek J Richard, Malcolm F White and Liza Cubeddu


3 November 2014

Two-step mechanism involving active-site conformational changes regulates human telomerase DNA binding
Christopher G. Tomlinson, Aaron L Moye, Jessica K Holien, Michael W Parker, Scott B Cohen and Tracy M Bryan


31 October 2014

Circular trimers of gelatinase B/ matrix metalloproteinase-9 constitute a distinct population of functional enzyme molecules differentially regulated by tissue inhibitor of metalloproteinases-1
Jennifer Vandooren, Benjamin Born, Inna Solomonov, Ewa Zajac, Radka Saldova, Michael Senske, Estefanía Ugarte-Berzal, Erik Martens, Philippe E. Van den Steen, Jo Van Damme, Angeles García-Pardo, Matheus Froeyen, Elena I. Deryugina, James P. Quigley, Søren K Moestrup, Pauline M. Rudd, Irit Sagi and Ghislain Opdenakker


Vinculin-dependent actin bundling regulates cell migration and traction forces
Karry M Jannie, Shawn M. Ellerbroek, Dennis W. Zhou, Sophia Chen, David J. Crompton, Andres J Garcia and Kris A. DeMali


29 October 2014

Eukaryotic elongation factor 2 kinase regulates the cold stress response by slowing translation elongation
John RP Knight, Amandine Bastide, Anne Roobol, Jo Roobol, Thomas John Jackson, Wahyu Utami, David A Barrett, C Mark Smales and A E Willis


The author has paid for access to this article to be freely available The clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases
James Ozanne, Alan R Prescott and Kristopher Clark


28 October 2014

Protein intrinsic disorder in Arabidopsis NAC transcription factors: Transcriptional activation by ANAC013 and ANAC046 and their interactions with Radical Induced Cell Death1
Charlotte O'Shea, Mikael Kryger, Emil G.P. Stender, Birthe B. Kragelund, Martin Willemoës and Karen Skriver


23 October 2014

Exchange protein directly activated by cAMP (EPAC1) modulates regulatory T-cell-mediated immune suppression
Muayad Almahariq, Fang Mei, Hui Wang, Anthony T. Cao, Suxia Yao, Lynn Soong, Jiaren Sun, Yingzi Cong, Ju Chen and Xiaodong Cheng


22 October 2014

Accelerated Publication
Late stages of the synchronized macrophage fusion in osteoclast formation depend on dynamin
Santosh K Verma, Evgenia Leikina, Kamran Melikov and Leonid V Chernomordik


21 October 2014

Accelerated Publication
Disruption of integrin−fibronectin complexes by allosteric but not ligand-mimetic inhibitors
A Paul Mould, Susan E Craig, Sarah K Byron, Martin J Humphries and Thomas A Jowitt


Identification of peptides in human Hsp20 and Hsp27 that possess molecular chaperone and anti-apoptotic activities
Rooban B Nahomi, Michael A DiMauro, Benlian Wang and Ram H Nagaraj


Structural determinants of host specificity of complement Factor H recruitment by Streptococcus pneumoniae
David Achila, Aizhuo Liu, Rahul Banerjee, Yue Li, Erik Martinez-Hackert, Jing-Ren Zhang and Honggao Yan


A cholesterol consensus motif is required for efficient intracellular transport and raft association of a group 2 HA from influenza virus
Maren de Vries, Andreas Herrmann and Michael Veit


20 October 2014

p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity
Anne Roobol, Jo Roobol, Amandine Bastide, John RP Knight, Anne E Willis and C Mark Smales


Cytoglobin ligand binding regulated by changing haem-co-ordination in response to intramolecular disulfide bond formation and lipid interaction
Penny Beckerson, Michael T Wilson, Dimitri A Svistunenko and Brandon J Reeder


15 October 2014

miR-29b modulates intestinal epithelium homoeostasis by repressing menin translation
Miao Ouyang, Weijie Su, Lan Xiao, Jaladanki N Rao, Liping Jiang, Yanwu Li, Douglas J. Turner, Myriam Gorospe and Jian-Ying Wang


Revisiting the Roco G-protein cycle
Susanne Terheyden, Franz Y Ho, Bernd Karl Gilsbach, Alfred Wittinghofer and Arjan Kortholt


13 October 2014

Osteopontin mediates mineralization and not osteogenic cell development in vitro
Erik Holm, Jared S Gleberzon, Yinyin Liao, Esben S Sørensen, Frank Beier, Graeme K Hunter and Harvey A Goldberg


9 October 2014

Trace analysis of methylated and hydroxymethylated cytosines in DNA by isotope-dilution LC–MS/MS: first evidence of DNA methylation in Caenorhabditis elegans
Chiung-Wen Hu, Jian-Lian Chen, Yu-Wen Hsu, Cheng-Chieh Yen and Mu-Rong Chao


The architecture of an Okazaki fragment-processing holoenzyme from the archaeon Sulfolobus solfataricus
Giuseppe Cannone, Yuli Xu, Thomas R. Beattie, Stephen D Bell and Laura Spagnolo


7 October 2014

Neutral sphingomyelinase-2 is a redox sensitive enzyme: role of catalytic cysteine residues in regulation of enzyme activity through changes in oligomeric state
P. Patrick Dotson II, Alexander A. Karakashian and Mariana N. Nikolova-Karakashian


Missing-in-Metastasis regulates cell motility and invasion via PTPδ-mediated changes in SRC activity
Fauzia Chaudhary, Robert Lucito and Nicholas K Tonks


Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding
Patrick R Visperas, Jonathan A Winger, Timothy M Horton, Neel H Shah, Diane J Aum, Alyssa Tao, Tiago Barros, Qingrong Yan, Chistopher G Wilson, Michelle R Arkin, Arthur Weiss and John Kuriyan


6 October 2014

Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification
Takuya Kitamura, Shuyu Takagi, Tatsuro Naganuma and Akio Kihara


3 October 2014

Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor
Vidhu Sharma, Preety Panwar, Anthony J O'Donoghue, Haoran Cui, Rafael V. C. Guido, Charles S. Craik and Dieter Bromme


Solution structures and dynamics of ADF/cofilins UNC-60A and UNC-60B from Caenorhabditis elegans
Vaibhav Kumar Shukla, Ashish Kabra, Diva Maheshwari, Rahul Yadav, Anupam Jain, Sarita Tripathi, Shoichiro Ono, Dinesh Kumar and Ashish Arora


Bioenergetic differences between MCF-7 and T47D breast cancer cells and their regulation by oestradiol and tamoxifen
Brandie N Radde, Margarita M Ivanova, Huy Xuan Mai, Joshua K Salabei, Bradford G Hill and Carolyn M Klinge


2 October 2014

Structure-based design and functional studies of novel noroviral 3C protease chimaeras offer insights into substrate specificity
Morgan R. Herod, Cynthia A. Prince, Rachel J. Skilton, Vernon K. Ward, Jonathan B. Cooper and Ian N. Clarke


1 October 2014

The SARS-coronavirus membrane protein induces apoptosis via interfering with PDK1–PKB/Akt signalling
Ho Tsoi, Li Li, Zhefan S Chen, Kwok-Fai Lau, Stephen Kwok-Wing Tsui and Ho-Yin Edwin Chan


Inpp5e increases the Rab5 association and phosphatidylinositol 3-phosphate accumulation at the phagosome through an interaction with Rab20
Tomohiro Segawa, Kaoru Hazeki, Kiyomi Nigorikawa, Shin Morioka, Ying Guo, Shunsuke Takasuga, Ken Asanuma and Osamu Hazeki


The disease-associated mutation of the mitochondrial thiol oxidase Erv1 impairs cofactor binding during its catalytic reaction
Efrain Ceh-Pavia, Swee Kim Ang, Michael P Spiller and Hui Lu


30 September 2014

DNA polymerase η is regulated by poly(rC)-binding protein 1 via mRNA stability
Cong Ren, Seong-Jun Cho, Yong-Sam Jung and Xinbin Chen


Aminoacetone oxidase from Streptococcus oligofermentans belongs to a new three-domain family of bacterial flavoproteins
Gianluca Molla, Marco Nardini, Paolo Motta, Paola D’Arrigo, Walter Panzeri and Loredano Pollegioni


25 September 2014

Identification of NOX2 regions for normal biosynthesis of cytochrome b558 in phagocytes highlighting essential residues for p22phox binding
Sylvain Beaumel, Didier Grunwald, Franck Fieschi and Marie José Stasia


A protein kinase screen of Neurospora crassa mutant strains reveals that the SNF1 protein kinase promotes glycogen synthase phosphorylation
Thiago De Souza Candido, Rodrigo Duarte Gonçalves, Ana Paula Felicio, Fernanda Zanolli Freitas, Fernanda Barbosa Cupertino, Ana Carolina Gomes Vieira De Carvalho and Maria Celia Bertolini


24 September 2014

The author has paid for access to this article to be freely available A context-independent N-glycan signal targets the misfolded extracellular domain of Arabidopsis STRUBBELIG to endoplasmic-reticulum-associated degradation
Silvia Hüttner, Christiane Veit, Ulrike Vavra, Jennifer Schoberer, Martina Dicker, Daniel Maresch, Friedrich Altmann and Richard Strasser


23 September 2014

Structural characterization of spinach ribulose-1,5-bisphosphate carboxylase/oxygenase activase isoforms reveals hexameric assemblies with increased thermal stability
Jeremy R Keown and Frederick Grant Pearce


Identification of amino acid determinants in CYP4B1 for optimal catalytic processing of 4-ipomeanol
Constanze Wiek, Eva Maria Schmidt, Katharina Röllecke, Marcel Freund, Mariko Nakano, Edward J Kelly, Wolfgang Kaisers, Vladimir Yarov-Yarovoy, Christof M Kramm, Allan E Rettie and Helmut Hanenberg


22 September 2014

The author has paid for access to this article to be freely available Comparisons of subunit 5A and 5B isoenzymes of yeast cytochrome c oxidase
Raksha Dodia, Brigitte Meunier, Christopher W.M. Kay and Peter R Rich


19 September 2014

Sulphonylurea receptors regulate the channel pore in ATP-sensitive potassium channels via an intersubunit salt bridge
David Lodwick, Richard D Rainbow, Hussein N Rubaiy, Mohammed Al Johi, Geerten W Vuister and Robert I Norman


29 September 2008

Curcumin, a dietary polyphenol, emerges as a novel inhibitor of DNA topoisomerase I of kinetoplastid parasite Leishmania donovani
Rakhee Das, Amit Roy, Agneyo Ganguly, Neeta Datta and Hemanta K Majumder