Welcome to your Biochemical Journal for the 21st Century

Biochemical Journal awarded the
ALPSP/Charlesworth Award for Best Online Journal

To help you get the best out of your visit to the Biochemical Journal, papers are divided into seven knowledge environments: Cell, Disease, Energy, Gene, Plant, Signal, Structure

NEW KNOWLEDGE ENVIRONMENT!
We've just launched a new knowledge environment, Metabolism, covering metabolic processes and their regulation from the cellular to the organismal level. Take a look today!

NEW KNOWLEDGE ENVIRONMENT - COMING SOON
We will also be launching a further new knowledge environment shortly - ChemBio - sign up to receive further information today!

Keep up with all the latest research in your area and read expert reviews and commentaries by selecting the relevant image icon above.

Submit your next paper and find out what publishing benefits we offer...

The Biochemical Journal is now fully compliant with funding body mandates including NIH. Read our FAQs

BJ Classics opens up over 100 years of archival material by highlighting seminal papers and people. Take a look today

Create your own personal space with My BJ where search strategies and content alerts can be set up to suit you! Register today or log in

New Online Comment facility for users enables you to post a comment on a paper.
Simply select the "Add a comment" link from the box in the top right-hand corner of the paper, log in to My BJ, then submit the Comment form.

Take a look at the five reviews in our series to celebrate the bicentenary of Darwin's birth and the 150th anniversary of the publication of “On the Origin of Species”.

To order your own unique collection of these five reviews at a special rate of £20 for Biochemical Society members and £25 for non members click here

Darwin, Dover, “Intelligent Design” and textbooks

by Kevin Padian and Nicholas Matzke examines the ongoing evolution-versus-creationism controversy in American jurisprudence. This review is now freely available to all users!

Genomic and structural aspects of protein evolution

by Cyrus Chothia and Julian Gough discusses the various roles played by protein domain duplication, domain combination and divergence, three key “drivers” in the evolution of new proteins and protein superfamilies.

Insulin/IGF-like signalling, the central nervous system and aging

by Susan Broughton and Linda Partridge discusses the current knowledge about the role of the central nervous system in IIS [insulin/IGF (insulin-like growth factor)-like signalling]-related extension of lifespan in model organisms.

The origin, evolution and structure of the protein world

by Gustavo Caetano-Anollés and colleagues examines the structure of the contemporary protein world, and discusses how evolutionary genomics and structural bioinformatics have helped in delineating the origin and history of modern proteins.

Evolution of protein phosphatases in plants and animals

by Greg Moorhead, Veerle De Wever, George Templeton and David Kerk discusses comprehensively the evolution of the three major families of protein phosphatases, highlighting examples of convergent evolution and phosphatases that are unique to plants.