BJ ChemBio Papers
AKT-ing out: SGK kinases come to the fore
Larissa S. Moniz and Bart Vanhaesebroeck..........e11‑e13
Published on the Internet 31 May 2013, doi:10.1042/BJ20130617
Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitorsEeva M. Sommer, Hannah Dry, Darren Cross, Sylvie Guichard, Barry R. Davies and Dario R. Alessi..........499‑508
Published as BJ Immediate Publication 15 April 2013, doi:10.1042/BJ20130342
Proteolytic activation of prochemerin by kallikrein 7 breaks an ionic linkage and results in C-terminal rearrangement
Stephan Schultz, Anja Saalbach, John T. Heiker, Rene Meier, Tristan Zellmann, Jan C. Simon and Annette G. Beck‑Sickinger..........271‑280
Published as BJ Immediate Publication 18 March 2013, doi:10.1042/BJ20121880
The muscarinic M3 acetylcholine receptor exists as two differently sized complexes at the plasma membrane
Suparna Patowary, Elisa Alvarez‑Curto, Tian‑Rui Xu, Jessica D. Holz, Julie A. Oliver, Graeme Milligan and Valerică Raicu..........303‑312
Published as BJ Immediate Publication 25 March 2013, doi:10.1042/BJ20121902
Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation
Daniela Meyer, Frank Sielaff, Maya Hammami, Eva Böttcher‑Friebertshäuser, Wolfgang Garten and Torsten Steinmetzer..........331‑343
Published as BJ Immediate Publication 25 March 2013, doi:10.1042/BJ20130101
FSL-61 is a 6-nitroquinolone fluorogenic probe for one-electron reductases in hypoxic cells
Jiechuang Su, Christopher P. Guise and William R. Wilson..........79‑86
Published as BJ Immediate Publication 12 March 2013, doi:10.1042/BJ20121695
Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes
Svend Kjær, Mark Linch, Andrew Purkiss, Brenda Kostelecky, Phillip P. Knowles, Carine Rosse, Philippe Riou, Christelle Soudy, Sarah Kaye, Bhavisha Patel, Erika Soriano, Judith Murray‑Rust, Caroline Barton, Christian Dillon, Jon Roffey, Peter J. Parker and Neil Q. McDonald..........329‑342
Published as BJ Immediate Publication 18 February 2013, doi:10.1042/BJ20121871
- Inhibition of human γ-glutamyl transpeptidase: development of more potent, physiologically relevant, uncompetitive inhibitors
- Stephanie Wickham, Nicholas Regan, Matthew B. West, Justin Thai, Paul F. Cook, Simon S. Terzyan, Pui Kai Li and Marie H. Hanigan..........547‑557
- Published as BJ Immediate Publication 10 January 2013, doi:10.1042/BJ20121435
- Abstract | Full text HTML | Full text PDF
- Stephanie Wickham, Nicholas Regan, Matthew B. West, Justin Thai, Paul F. Cook, Simon S. Terzyan, Pui Kai Li and Marie H. Hanigan..........547‑557
- p-Sulfonato-calix[n]arenes inhibit staphylococcal bicomponent leukotoxins by supramolecular interactions
- Benoît‑Joseph Laventie, Cristina Potrich, Cédric Atmanène, Maher Saleh, Olivier Joubert, Gabriella Viero, Christoph Bachmeyer, Valeria Antonini, Ines Mancini, Sarah Cianferani‑Sanglier, Daniel Keller, Didier A. Colin, Tristan Bourcier, Gregor Anderluh, Alain van Dorsselaer, Mauro Dalla Serra and Gilles Prévost..........559‑571
- Published as BJ Immediate Publication 3 January 2013, doi:10.1042/BJ20121628
- Abstract | Full text HTML | Full text PDF | Online Data
- Benoît‑Joseph Laventie, Cristina Potrich, Cédric Atmanène, Maher Saleh, Olivier Joubert, Gabriella Viero, Christoph Bachmeyer, Valeria Antonini, Ines Mancini, Sarah Cianferani‑Sanglier, Daniel Keller, Didier A. Colin, Tristan Bourcier, Gregor Anderluh, Alain van Dorsselaer, Mauro Dalla Serra and Gilles Prévost..........559‑571
- A novel small-molecule screening strategy identifies mitoxantrone as a RhoGTPase inhibitor
- Aurélien Bidaud‑Meynard, Daniela Arma, Said Taouji, Michel Laguerre, Jean Dessolin, Jean Rosenbaum, Eric Chevet and Violaine Moreau..........55‑62
- Published as BJ Immediate Publication 27 November 2012, doi:10.1042/BJ20120572
- Abstract | Full text HTML | Full text PDF | Online Data
- Aurélien Bidaud‑Meynard, Daniela Arma, Said Taouji, Michel Laguerre, Jean Dessolin, Jean Rosenbaum, Eric Chevet and Violaine Moreau..........55‑62
- Tumour cells can employ extracellular Ins(1,2,3,4,5,6)P6 and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation
- Sabine Windhorst, Hongying Lin, Christine Blechner, Werner Fanick, Laura Brandt, Maria A. Brehm and Georg W. Mayr..........115‑125
- Published as BJ Immediate Publication 28 November 2012, doi:10.1042/BJ20121524
- Abstract | Full text HTML | Full text PDF | Online Data
- Sabine Windhorst, Hongying Lin, Christine Blechner, Werner Fanick, Laura Brandt, Maria A. Brehm and Georg W. Mayr..........115‑125
- Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes
- Zoran Radić, Trevor Dale, Zrinka Kovarik, Suzana Berend, Edzna Garcia, Limin Zhang, Gabriel Amitai, Carol Green, Božica Radić, Brendan M. Duggan, Dariush Ajami, Julius Rebek and Palmer Taylor..........231‑242
- Published as BJ Immediate Publication 6 December 2012, doi:10.1042/BJ20121612
- Abstract | Full text HTML | Full text PDF | Online Data
- Zoran Radić, Trevor Dale, Zrinka Kovarik, Suzana Berend, Edzna Garcia, Limin Zhang, Gabriel Amitai, Carol Green, Božica Radić, Brendan M. Duggan, Dariush Ajami, Julius Rebek and Palmer Taylor..........231‑242
- Human cytoplasmic ProX edits mischarged tRNAPro with amino acid but not tRNA specificity
- Liang‑Liang Ruan, Xiao‑Long Zhou, Min Tan and En‑Duo Wang..........243‑252
- Published as BJ Immediate Publication 5 December 2012, doi:10.1042/BJ20121493
- Abstract | Full text HTML | Full text PDF | Online Data
- Liang‑Liang Ruan, Xiao‑Long Zhou, Min Tan and En‑Duo Wang..........243‑252
- Rapid purification of ribosomal particles assembled on histone H4 mRNA: a new method based on mRNA–DNA chimaeras
- Lydia Prongidi‑Fix, Laure Schaeffer, Angelita Simonetti, Sharief Barends, Jean‑François Ménétret, Bruno P. Klaholz, Gilbert Eriani and Franck Martin..........719‑728
- Published as BJ Immediate Publication 12 November 2012, doi:10.1042/BJ20121211
- Abstract | Full text HTML | Full text PDF
- Lydia Prongidi‑Fix, Laure Schaeffer, Angelita Simonetti, Sharief Barends, Jean‑François Ménétret, Bruno P. Klaholz, Gilbert Eriani and Franck Martin..........719‑728
- Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase
- Elena M. Sánchez‑Fernández, Hanna Tarhonskaya, Khalid Al‑Qahtani, Richard J. Hopkinson, James S. O. McCullagh, Christopher J. Schofield and Emily Flashman..........491‑496
- Published as BJ Immediate Publication 24 October 2012, doi:10.1042/BJ20121155
- Abstract | Full text HTML | Full text PDF | Online Data
- Elena M. Sánchez‑Fernández, Hanna Tarhonskaya, Khalid Al‑Qahtani, Richard J. Hopkinson, James S. O. McCullagh, Christopher J. Schofield and Emily Flashman..........491‑496
- Design of a heterotetravalent synthetic allergen that reflects epitope heterogeneity and IgE antibody variability to study mast cell degranulation
- Michael W. Handlogten, Tanyel Kiziltepe and Basar Bilgicer..........91‑99
- Published as BJ Immediate Publication 11 October 2012, doi:10.1042/BJ20121088
- Abstract | Full text HTML | Full text PDF | Online Data
- Michael W. Handlogten, Tanyel Kiziltepe and Basar Bilgicer..........91‑99
- Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum
- Shaun B. Reeksting, Ingrid B. Müller, Pieter B. Burger, Emmanuel S. Burgos, Laurent Salmon, Abraham I. Louw, Lyn‑Marie Birkholtz and Carsten Wrenger..........175‑187
- Published as BJ Immediate Publication 8 October 2012, doi:10.1042/BJ20120925
- Abstract | Full text HTML | Full text PDF | Online Data
- Shaun B. Reeksting, Ingrid B. Müller, Pieter B. Burger, Emmanuel S. Burgos, Laurent Salmon, Abraham I. Louw, Lyn‑Marie Birkholtz and Carsten Wrenger..........175‑187
- Mislocalization and inhibition of acetyl-CoA carboxylase 1 by a synthetic small molecule
- Dongju Jung, Lutfi Abu‑Elheiga, Rie Ayuzawa, Ziwei Gu, Takashi Shirakawa, Yukio Fujiki, Norio Nakatsuji, Salih J. Wakil and Motonari Uesugi..........409‑416
- Published as BJ Immediate Publication 15 October 2012, doi:10.1042/BJ20121158
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Dongju Jung, Lutfi Abu‑Elheiga, Rie Ayuzawa, Ziwei Gu, Takashi Shirakawa, Yukio Fujiki, Norio Nakatsuji, Salih J. Wakil and Motonari Uesugi..........409‑416
- An aminoquinazoline inhibitor of the essential bacterial cell wall synthetic enzyme GlmU has a unique non-protein-kinase-like binding mode
- Nicholas A. Larsen, Tory J. Nash, Marshall Morningstar, Adam B. Shapiro, Camil Joubran, Carolyn J. Blackett, Arthur D. Patten, P. Ann Boriack‑Sjodin and Peter Doig..........405‑413
- Published as BJ Immediate Publication 22 June 2012, doi:10.1042/BJ20120596
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Nicholas A. Larsen, Tory J. Nash, Marshall Morningstar, Adam B. Shapiro, Camil Joubran, Carolyn J. Blackett, Arthur D. Patten, P. Ann Boriack‑Sjodin and Peter Doig..........405‑413
- Novel atypical PKC inhibitors prevent vascular endothelial growth factor-induced blood–retinal barrier dysfunction
- Paul M. Titchenell, Cheng‑Mao Lin, Jason M. Keil, Jeffrey M. Sundstrom, Charles D. Smith and David A. Antonetti..........455‑467
- Published as BJ Immediate Publication 22 June 2012, doi:10.1042/BJ20111961
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Paul M. Titchenell, Cheng‑Mao Lin, Jason M. Keil, Jeffrey M. Sundstrom, Charles D. Smith and David A. Antonetti..........455‑467
- Erythrocyte storage increases rates of NO and nitrite scavenging: implications for transfusion-related toxicity
- Ryan Stapley, Benjamin Y. Owusu, Angela Brandon, Marianne Cusick, Cilina Rodriguez, Marisa B. Marques, Jeffrey D. Kerby, Scott R. Barnum, Jordan A. Weinberg, Jack R. Lancaster and Rakesh P. Patel..........499‑508
- Published as BJ Immediate Publication 21 June 2012, doi:10.1042/BJ20120675
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Ryan Stapley, Benjamin Y. Owusu, Angela Brandon, Marianne Cusick, Cilina Rodriguez, Marisa B. Marques, Jeffrey D. Kerby, Scott R. Barnum, Jordan A. Weinberg, Jack R. Lancaster and Rakesh P. Patel..........499‑508
- Revealing a natural marine product as a novel agonist for retinoic acid receptors with a unique binding mode and inhibitory effects on cancer cells
- Shanshan Wang, Zhao Wang, Shengchen Lin, Weili Zheng, Rui Wang, Shikai Jin, Jinan Chen, Lihua Jin and Yong Li..........79‑87
- Published as BJ Immediate Publication 29 May 2012, doi:10.1042/BJ20120726
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Online commentary
- Shanshan Wang, Zhao Wang, Shengchen Lin, Weili Zheng, Rui Wang, Shikai Jin, Jinan Chen, Lihua Jin and Yong Li..........79‑87
- Mutational analysis of putative phosphate- and proton-binding sites in the Saccharomyces cerevisiae Pho84 phosphate:H+ transceptor and its effect on signalling to the PKA and PHO pathways
- Dieter R. Samyn, Lorena Ruiz‑Pávon, Michael R. Andersson, Yulia Popova, Johan M. Thevelein and Bengt L. Persson..........413‑422
- Published as BJ Immediate Publication 15 May 2012, doi:10.1042/BJ20112086
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Dieter R. Samyn, Lorena Ruiz‑Pávon, Michael R. Andersson, Yulia Popova, Johan M. Thevelein and Bengt L. Persson..........413‑422
- Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor
- Ilaria Lamberto, Haina Qin, Roberta Noberini, Lakshmanane Premkumar, Caroline Bourgin, Stefan J. Riedl, Jianxing Song and Elena B. Pasquale..........47‑56
- Published as BJ Immediate Publication 10 April 2012, doi:10.1042/BJ20120408
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Ilaria Lamberto, Haina Qin, Roberta Noberini, Lakshmanane Premkumar, Caroline Bourgin, Stefan J. Riedl, Jianxing Song and Elena B. Pasquale..........47‑56
- Bax and Bcl-xL exert their regulation on different sites of the ceramide channel
- Meenu N. Perera, Shang H. Lin, Yuri K. Peterson, Alicja Bielawska, Zdzislaw M. Szulc, Robert Bittman and Marco Colombini..........81‑91
- Published as BJ Immediate Publication 11 April 2012, doi:10.1042/BJ20112103
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Meenu N. Perera, Shang H. Lin, Yuri K. Peterson, Alicja Bielawska, Zdzislaw M. Szulc, Robert Bittman and Marco Colombini..........81‑91
- The disordered N-terminal region of dengue virus capsid protein contains a lipid-droplet-binding motif
- Ivo C. Martins, Francisco Gomes‑Neto, André F. Faustino, Filomena A. Carvalho, Fabiana A. Carneiro, Patricia T. Bozza, Ronaldo Mohana‑Borges, Miguel A. R. B. Castanho, Fábio C. L. Almeida, Nuno C. Santos and Andrea T. Da Poian..........405‑415
- Published as BJ Immediate Publication 19 March 2012, doi:10.1042/BJ20112219
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Ivo C. Martins, Francisco Gomes‑Neto, André F. Faustino, Filomena A. Carvalho, Fabiana A. Carneiro, Patricia T. Bozza, Ronaldo Mohana‑Borges, Miguel A. R. B. Castanho, Fábio C. L. Almeida, Nuno C. Santos and Andrea T. Da Poian..........405‑415
- Definition of the binding mode of a new class of phosphoinositide 3-kinase α-selective inhibitors using in vitro mutagenesis of non-conserved amino acids and kinetic analysis
- Zhaohua Zheng, Syazwani I. Amran, Jiuxiang Zhu, Oleg Schmidt‑Kittler, Kenneth W. Kinzler, Bert Vogelstein, Peter R. Shepherd, Philip E. Thompson and Ian G. Jennings..........529‑535
- Published as BJ Immediate Publication 13 April 2012, doi:10.1042/BJ20120499
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Zhaohua Zheng, Syazwani I. Amran, Jiuxiang Zhu, Oleg Schmidt‑Kittler, Kenneth W. Kinzler, Bert Vogelstein, Peter R. Shepherd, Philip E. Thompson and Ian G. Jennings..........529‑535
- Generation of free ubiquitin chains is up-regulated in stress and facilitated by the HECT domain ubiquitin ligases UFD4 and HUL5
- Ori Braten, Nitzan Shabek, Yelena Kravtsova‑Ivantsiv and Aaron Ciechanover..........611‑617
- Published as BJ Immediate Publication 13 April 2012, doi:10.1042/BJ20111840
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Ori Braten, Nitzan Shabek, Yelena Kravtsova‑Ivantsiv and Aaron Ciechanover..........611‑617
- Building a better sphingosine kinase-1 inhibitor
- Kevin R. Lynch..........e1‑e2
- Published on the Internet 26 April 2012, doi:10.1042/BJ20120567
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Accompanying paper
- Kevin R. Lynch..........e1‑e2
- Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1
- Mark E. Schnute, Matthew D. McReynolds, Tom Kasten, Matthew Yates, Gina Jerome, John W. Rains, Troii Hall, Jill Chrencik, Michelle Kraus, Ciaran N. Cronin, Matthew Saabye, Maureen K. Highkin, Richard Broadus, Shinji Ogawa, Kristin Cukyne, Laura E. Zawadzke, Vincent Peterkin, Kaliapan Iyanar, Jeffrey A. Scholten, Jay Wendling, Hideji Fujiwara, Olga Nemirovskiy, Arthur J. Wittwer and Marek M. Nagiec..........79‑88
- Published as BJ Immediate Publication 8 March 2012, doi:10.1042/BJ20111929
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Online commentary
- Mark E. Schnute, Matthew D. McReynolds, Tom Kasten, Matthew Yates, Gina Jerome, John W. Rains, Troii Hall, Jill Chrencik, Michelle Kraus, Ciaran N. Cronin, Matthew Saabye, Maureen K. Highkin, Richard Broadus, Shinji Ogawa, Kristin Cukyne, Laura E. Zawadzke, Vincent Peterkin, Kaliapan Iyanar, Jeffrey A. Scholten, Jay Wendling, Hideji Fujiwara, Olga Nemirovskiy, Arthur J. Wittwer and Marek M. Nagiec..........79‑88
- An activity-based probe reveals dynamic protein–protein interactions mediating IGF-1R transactivation by the GABAB receptor
- Xin Lin, Xin Li, Ming Jiang, Linhai Chen, Chanjuan Xu, Wenhua Zhang, Han Zhao, Bing Sun, Xiaoli Xu, Fajun Nan and Jianfeng Liu..........627‑634
- Published as BJ Immediate Publication 7 March 2012, doi:10.1042/BJ20120188
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Xin Lin, Xin Li, Ming Jiang, Linhai Chen, Chanjuan Xu, Wenhua Zhang, Han Zhao, Bing Sun, Xiaoli Xu, Fajun Nan and Jianfeng Liu..........627‑634
- Oxygen activation in neuronal NO synthase: resolving the consecutive mono-oxygenation steps
- Davide Papale, Chiara Bruckmann, Ben Gazur, Caroline S. Miles, Christopher G. Mowat and Simon Daff..........505‑514
- Published as BJ Immediate Publication 3 February 2012, doi:10.1042/BJ20111644
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Davide Papale, Chiara Bruckmann, Ben Gazur, Caroline S. Miles, Christopher G. Mowat and Simon Daff..........505‑514
- Green tea polyphenol EGCG induces lipid-raft clustering and apoptotic cell death by activating protein kinase Cδ and acid sphingomyelinase through a 67 kDa laminin receptor in multiple myeloma cells
- Shuntaro Tsukamoto, Keisuke Hirotsu, Motofumi Kumazoe, Yoko Goto, Kaori Sugihara, Takafumi Suda, Yukari Tsurudome, Takashi Suzuki, Shuya Yamashita, Yoonhee Kim, Yuhui Huang, Koji Yamada and Hirofumi Tachibana..........525‑534
- Published as BJ Immediate Publication 19 January 2012, doi:10.1042/BJ20111837
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Shuntaro Tsukamoto, Keisuke Hirotsu, Motofumi Kumazoe, Yoko Goto, Kaori Sugihara, Takafumi Suda, Yukari Tsurudome, Takashi Suzuki, Shuya Yamashita, Yoonhee Kim, Yuhui Huang, Koji Yamada and Hirofumi Tachibana..........525‑534
- First identification of small-molecule inhibitors of Pontin by combining virtual screening and enzymatic assay
- Judith Elkaim, Michel Castroviejo, Driss Bennani, Said Taouji, Nathalie Allain, Michel Laguerre, Jean Rosenbaum, Jean Dessolin and Patrick Lestienne..........549‑559
- Published as BJ Immediate Publication 24 January 2012, doi:10.1042/BJ20111779
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Judith Elkaim, Michel Castroviejo, Driss Bennani, Said Taouji, Nathalie Allain, Michel Laguerre, Jean Rosenbaum, Jean Dessolin and Patrick Lestienne..........549‑559
- Targeting Lyn tyrosine kinase through protein fusions encompassing motifs of Cbp (Csk-binding protein) and the SOCS box of SOCS1
- R. J. Whiting, C. J. Payne, J. Satiaputra, N. Kucera, T. W. Qiu, S. Irtegun, N. J. Gunn, N. S. Slavova‑Azmanova, T. D. Mulhern and E. Ingley..........585
- Published on the Internet 27 March 2012
- Legacy HTML | Full text PDF
- R. J. Whiting, C. J. Payne, J. Satiaputra, N. Kucera, T. W. Qiu, S. Irtegun, N. J. Gunn, N. S. Slavova‑Azmanova, T. D. Mulhern and E. Ingley..........585
- New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries
- Nunzianna Doti, Pasqualina L. Scognamiglio, Stefania Madonna, Claudia Scarponi, Menotti Ruvo, Giuseppe Perretta, Cristina Albanesi and Daniela Marasco..........231‑240
- Published as BJ Immediate Publication 14 December 2011, doi:10.1042/BJ20111647
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Nunzianna Doti, Pasqualina L. Scognamiglio, Stefania Madonna, Claudia Scarponi, Menotti Ruvo, Giuseppe Perretta, Cristina Albanesi and Daniela Marasco..........231‑240
- Fluorescence detection of GDP in real time with the reagentless biosensor rhodamine–ParM
- Simone Kunzelmann and Martin R. Webb..........43‑49
- Published as BJ Immediate Publication 3 August 2011, doi:10.1042/BJ20110349
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Simone Kunzelmann and Martin R. Webb..........43‑49
- Tissue- and paralogue-specific functions of acyl-CoA-binding proteins in lipid metabolism in Caenorhabditis elegans
- Ida C. Elle, Karina T. Simonsen, Louise C. B. Olsen, Pernille K. Birck, Sidse Ehmsen, Simon Tuck, Thuc T. Le and Nils J. Færgeman..........231‑241
- Published as BJ Immediate Publication 4 May 2011, doi:10.1042/BJ20102099
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Ida C. Elle, Karina T. Simonsen, Louise C. B. Olsen, Pernille K. Birck, Sidse Ehmsen, Simon Tuck, Thuc T. Le and Nils J. Færgeman..........231‑241
- Hexokinase II acts through UCP3 to suppress mitochondrial reactive oxygen species production and maintain aerobic respiration
- Ryan J. Mailloux, Tyler Dumouchel, Céline Aguer, Rob deKemp, Rob Beanlands and Mary‑Ellen Harper..........301‑311
- Published as BJ Immediate Publication 10 May 2011, doi:10.1042/BJ20110571
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Multimedia
- Ryan J. Mailloux, Tyler Dumouchel, Céline Aguer, Rob deKemp, Rob Beanlands and Mary‑Ellen Harper..........301‑311
- Manifold effects of palmitoylcarnitine on endoplasmic reticulum metabolism: 11β-hydroxysteroid dehydrogenase 1, flux through hexose-6-phosphate dehydrogenase and NADPH concentration
- Xudong Wang, Gail J. Mick, Edmund Maser and Kenneth McCormick..........109‑115
- Published as BJ Immediate Publication 15 April 2011, doi:10.1042/BJ20102069
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Xudong Wang, Gail J. Mick, Edmund Maser and Kenneth McCormick..........109‑115
- FAT/CD36 is located on the outer mitochondrial membrane, upstream of long-chain acyl-CoA synthetase, and regulates palmitate oxidation
- Brennan K. Smith, Swati S. Jain, Stéphanie Rimbaud, Aaron Dam, Joe Quadrilatero, Renée Ventura‑Clapier, Arend Bonen and Graham P. Holloway..........125‑134
- Published as BJ Immediate Publication 4 April 2011, doi:10.1042/BJ20101861
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Brennan K. Smith, Swati S. Jain, Stéphanie Rimbaud, Aaron Dam, Joe Quadrilatero, Renée Ventura‑Clapier, Arend Bonen and Graham P. Holloway..........125‑134
- OAT2 catalyses efflux of glutamate and uptake of orotic acid
- Christian Fork, Tim Bauer, Stefan Golz, Andreas Geerts, Jessica Weiland, Domenico Del Turco, Edgar Schömig and Dirk Gründemann..........305‑312
- Published as BJ Immediate Publication 30 March 2011, doi:10.1042/BJ20101904
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Christian Fork, Tim Bauer, Stefan Golz, Andreas Geerts, Jessica Weiland, Domenico Del Turco, Edgar Schömig and Dirk Gründemann..........305‑312
- Alternative affinity tools: more attractive than antibodies?
- Vincent J. B. Ruigrok, Mark Levisson, Michel H. M. Eppink, Hauke Smidt and John van der Oost..........1‑13
- Published on the Internet 27 April 2011, doi:10.1042/BJ20101860
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Vincent J. B. Ruigrok, Mark Levisson, Michel H. M. Eppink, Hauke Smidt and John van der Oost..........1‑13
- Cyclic lipopeptide antibiotics bind to the N-terminal domain of the prokaryotic Hsp90 to inhibit the chaperone activity
- Shun Minagawa, Yasumitsu Kondoh, Keigo Sueoka, Hiroyuki Osada and Hitoshi Nakamoto..........237‑246
- Published as BJ Immediate Publication 7 July 2011, doi:10.1042/BJ20100743
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Shun Minagawa, Yasumitsu Kondoh, Keigo Sueoka, Hiroyuki Osada and Hitoshi Nakamoto..........237‑246
- Identification of a DNA aptamer that inhibits sclerostin's antagonistic effect on Wnt signalling
- Ka To Shum, Celine Chan, Ching‑Man Leung and Julian A. Tanner..........493‑501
- Published as BJ Immediate Publication 4 January 2011, doi:10.1042/BJ20101096
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Ka To Shum, Celine Chan, Ching‑Man Leung and Julian A. Tanner..........493‑501
- Biological signalling activity measurements using mass spectrometry
- Pedro R. Cutillas and Claus Jørgensen..........189‑199
- Published on the Internet 11 February 2011, doi:10.1042/BJ20101974
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Pedro R. Cutillas and Claus Jørgensen..........189‑199
- Optical switch probes and optical lock-in detection (OLID) imaging microscopy: high-contrast fluorescence imaging within living systems
- Yuling Yan, M. Emma Marriott, Chutima Petchprayoon and Gerard Marriott..........411‑422
- Published on the Internet 14 January 2011, doi:10.1042/BJ20100992
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Yuling Yan, M. Emma Marriott, Chutima Petchprayoon and Gerard Marriott..........411‑422
- For a PDK1 inhibitor, the substrate matters
- Zachary A. Knight..........e1‑e2
- Published on the Internet 22 December 2010, doi:10.1042/BJ20102038
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Accompanying Paper
- Zachary A. Knight..........e1‑e2
- Surprising toxicity and assembly behaviour of amyloid β-protein oxidized to sulfone
- Panchanan Maiti, Roberto Piacentini, Cristian Ripoli, Claudio Grassi and Gal Bitan..........323‑332
- Published as BJ Immediate Publication 2 November 2010, doi:10.1042/BJ20101391
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Panchanan Maiti, Roberto Piacentini, Cristian Ripoli, Claudio Grassi and Gal Bitan..........323‑332
- Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1
- Ayaz Najafov, Eeva M. Sommer, Jeffrey M. Axten, M. Phillip Deyoung and Dario R. Alessi..........357‑369
- Published as BJ Immediate Publication 18 November 2010, doi:10.1042/BJ20101732
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online commentary
- Ayaz Najafov, Eeva M. Sommer, Jeffrey M. Axten, M. Phillip Deyoung and Dario R. Alessi..........357‑369
- Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of β-arrestin-2 and activate Gα13
- Laura Jenkins, Jose Brea, Nicola J. Smith, Brian D. Hudson, Graeme Reilly, Nia J. Bryant, Marian Castro, María‑Isabel Loza and Graeme Milligan..........451‑459
- Published as BJ Immediate Publication 5 October 2010, doi:10.1042/BJ20101287
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Laura Jenkins, Jose Brea, Nicola J. Smith, Brian D. Hudson, Graeme Reilly, Nia J. Bryant, Marian Castro, María‑Isabel Loza and Graeme Milligan..........451‑459
- Erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) blocks differentiation and maintains the expression of pluripotency markers in human embryonic stem cells
- Peter Burton, David R. Adams, Achamma Abraham, Robert W. Allcock, Zhong Jiang, Angela McCahill, Jane Gilmour, John McAbney, Alexandra Kaupisch, Nicole M. Kane, George S. Baillie, Andrew H. Baker, Graeme Milligan, Miles D. Houslay and Joanne C. Mountford..........575‑584
- Published as BJ Immediate Publication 5 October 2010, doi:10.1042/BJ20100726
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Peter Burton, David R. Adams, Achamma Abraham, Robert W. Allcock, Zhong Jiang, Angela McCahill, Jane Gilmour, John McAbney, Alexandra Kaupisch, Nicole M. Kane, George S. Baillie, Andrew H. Baker, Graeme Milligan, Miles D. Houslay and Joanne C. Mountford..........575‑584
- High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules
- Paul D. Andrews, Melissa Becroft, Anders Aspegren, Jane Gilmour, Martyn J. James, Scott McRae, Robert Kime, Robert W. Allcock, Achamma Abraham, Zhong Jiang, Raimund Strehl, Joanne C. Mountford, Graeme Milligan, Miles D. Houslay, David R. Adams and Julie A. Frearson..........21‑33
- Published as BJ Immediate Publication 20 September 2010, doi:10.1042/BJ20101022
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Paul D. Andrews, Melissa Becroft, Anders Aspegren, Jane Gilmour, Martyn J. James, Scott McRae, Robert Kime, Robert W. Allcock, Achamma Abraham, Zhong Jiang, Raimund Strehl, Joanne C. Mountford, Graeme Milligan, Miles D. Houslay, David R. Adams and Julie A. Frearson..........21‑33
- A new tool to dissect the function of p70 S6 kinase
- Benoit Bilanges and Bart Vanhaesebroeck..........e1‑e3
- Published on the Internet 28 September 2010, doi:10.1042/BJ20101445
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Accompanying paper
- Benoit Bilanges and Bart Vanhaesebroeck..........e1‑e3
- Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase
- Lloyd T. Morgan, Christopher P. Thomas, Hartmut Kühn and Valerie B. O'Donnell..........141‑148
- Published as BJ Immediate Publication 23 July 2010, doi:10.1042/BJ20100415
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Lloyd T. Morgan, Christopher P. Thomas, Hartmut Kühn and Valerie B. O'Donnell..........141‑148
- Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)
- Laura R. Pearce, Gordon R. Alton, Daniel T. Richter, John C. Kath, Laura Lingardo, Justin Chapman, Catherine Hwang and Dario R. Alessi..........245‑255
- Published as BJ Immediate Publication 12 August 2010, doi:10.1042/BJ20101024
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Online Commentary
- Laura R. Pearce, Gordon R. Alton, Daniel T. Richter, John C. Kath, Laura Lingardo, Justin Chapman, Catherine Hwang and Dario R. Alessi..........245‑255
- Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localization
- Nicolas Dzamko, Maria Deak, Faycal Hentati, Alastair D. Reith, Alan R. Prescott, Dario R. Alessi and R. Jeremy Nichols..........405‑413
- Published as BJ Immediate Publication 21 July 2010, doi:10.1042/BJ20100784
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Nicolas Dzamko, Maria Deak, Faycal Hentati, Alastair D. Reith, Alan R. Prescott, Dario R. Alessi and R. Jeremy Nichols..........405‑413
- Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S β5-subunit
- Christopher Blackburn, Kenneth M. Gigstad, Paul Hales, Khristofer Garcia, Matthew Jones, Frank J. Bruzzese, Cynthia Barrett, Jane X. Liu, Teresa A. Soucy, Darshan S. Sappal, Nancy Bump, Edward J. Olhava, Paul Fleming, Lawrence R. Dick, Christopher Tsu, Michael D. Sintchak and Jonathan L. Blank..........461‑476
- Published as BJ Immediate Publication 15 July 2010, doi:10.1042/BJ20100383
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Christopher Blackburn, Kenneth M. Gigstad, Paul Hales, Khristofer Garcia, Matthew Jones, Frank J. Bruzzese, Cynthia Barrett, Jane X. Liu, Teresa A. Soucy, Darshan S. Sappal, Nancy Bump, Edward J. Olhava, Paul Fleming, Lawrence R. Dick, Christopher Tsu, Michael D. Sintchak and Jonathan L. Blank..........461‑476
- Identification of broad-based HIV-1 protease inhibitors from combinatorial libraries
- Max W. Chang, Michael J. Giffin, Rolf Muller, Jeremiah Savage, Ying C. Lin, Sukwon Hong, Wei Jin, Landon R. Whitby, John H. Elder, Dale L. Boger and Bruce E. Torbett..........527‑532
- Published as BJ Immediate Publication 27 May 2010, doi:10.1042/BJ20091645
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Max W. Chang, Michael J. Giffin, Rolf Muller, Jeremiah Savage, Ying C. Lin, Sukwon Hong, Wei Jin, Landon R. Whitby, John H. Elder, Dale L. Boger and Bruce E. Torbett..........527‑532
- Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents
- Emily Flashman, Sarah L. Davies, Kar Kheng Yeoh and Christopher J. Schofield..........135‑142
- Published as BJ Immediate Publication 8 January 2010, doi:10.1042/BJ20091609
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Emily Flashman, Sarah L. Davies, Kar Kheng Yeoh and Christopher J. Schofield..........135‑142
- Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation<
- Philip Cohen..........53‑54
- Published on the Internet 14 December 2009, doi:10.1042/BJ20091428
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Philip Cohen..........53‑54
- Novel compound with potential of an antibacterial drug targets FtsZ protein
- Dipak Dasgupta..........e1‑e3
- Published on the Internet 14 September 2009, doi:10.1042/BJ20091226
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Accompanying paper
- Dipak Dasgupta..........e1‑e3
- Promoting assembly and bundling of FtsZ as a strategy to inhibit bacterial cell division: a new approach for developing novel antibacterial drugs
- Tushar K. Beuria, Parminder Singh, Avadhesha Surolia and Dulal Panda..........61‑69
- Published as BJ Immediate Publication 7 July 2009, doi:10.1042/BJ20090817
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data | Online commentary
- Tushar K. Beuria, Parminder Singh, Avadhesha Surolia and Dulal Panda..........61‑69
- 8-Bromo-cyclic inosine diphosphoribose: towards a selective cyclic ADP-ribose agonist
- Tanja Kirchberger, Christelle Moreau, Gerd K. Wagner, Ralf Fliegert, Cornelia C. Siebrands, Merle Nebel, Frederike Schmid, Angelika Harneit, Francesca Odoardi, Alexander Flügel, Barry V. L. Potter and Andreas H. Guse..........139‑149
- Published as BJ Immediate Publication 3 June 2009, doi:10.1042/BJ20082308
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- Tanja Kirchberger, Christelle Moreau, Gerd K. Wagner, Ralf Fliegert, Cornelia C. Siebrands, Merle Nebel, Frederike Schmid, Angelika Harneit, Francesca Odoardi, Alexander Flügel, Barry V. L. Potter and Andreas H. Guse..........139‑149
- Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases
- Daniel J. Sexton, Ting Chen, Diana Martik, Petr Kuzmic, Guannan Kuang, Jie Chen, Andrew E. Nixon, Bruce L. Zuraw, Rosanna M. Forteza, William M. Abraham and Clive R. Wood..........383‑392
- Published as BJ Immediate Publication 16 June 2009, doi:10.1042/BJ20090010
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Daniel J. Sexton, Ting Chen, Diana Martik, Petr Kuzmic, Guannan Kuang, Jie Chen, Andrew E. Nixon, Bruce L. Zuraw, Rosanna M. Forteza, William M. Abraham and Clive R. Wood..........383‑392
- Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2
- Giorgio Cozza, Marco Mazzorana, Elena Papinutto, Jenny Bain, Matthew Elliott, Giovanni di Maira, Alessandra Gianoncelli, Mario A. Pagano, Stefania Sarno, Maria Ruzzene, Roberto Battistutta, Flavio Meggio, Stefano Moro, Giuseppe Zagotto and Lorenzo A. Pinna..........387‑395
- Published as BJ Immediate Publication 11 May 2009, doi:10.1042/BJ20090069
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Giorgio Cozza, Marco Mazzorana, Elena Papinutto, Jenny Bain, Matthew Elliott, Giovanni di Maira, Alessandra Gianoncelli, Mario A. Pagano, Stefania Sarno, Maria Ruzzene, Roberto Battistutta, Flavio Meggio, Stefano Moro, Giuseppe Zagotto and Lorenzo A. Pinna..........387‑395
- Artificial β-defensin based on a minimal defensin template
- Nikolinka Antcheva, Francesca Morgera, Luisa Creatti, Lisa Vaccari, Ulrike Pag, Sabrina Pacor, Yechiel Shai, Hans‑Georg Sahl and Alessandro Tossi..........435‑447
- Published as BJ Immediate Publication 19 May 2009, doi:10.1042/BJ20082242
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Data
- Nikolinka Antcheva, Francesca Morgera, Luisa Creatti, Lisa Vaccari, Ulrike Pag, Sabrina Pacor, Yechiel Shai, Hans‑Georg Sahl and Alessandro Tossi..........435‑447
- Drug screening by crossing membranes: a novel approach to identification of trypanocides
- M. C. Field..........e1–e3
- Published on the Internet 27 March 2009, doi:10.1042/BJ20090283
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Accompanying paper
- M. C. Field..........e1–e3
- Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities
- B. Patham, J. Duffy, A. Lane, R.C. Davis, P. Wipf, S.W. Fewell, J.L. Brodsky and K. Mensa-Wilmot..........507–517
- Published as BJ Immediate Publication 5 February 2009, doi:10.1042/BJ20081787
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF | Online Commentary
- B. Patham, J. Duffy, A. Lane, R.C. Davis, P. Wipf, S.W. Fewell, J.L. Brodsky and K. Mensa-Wilmot..........507–517
- Development of an insect-cell-based assay for detection of kinase inhibition using NF-κB-inducing kinase as a paradigm
- N.J. Hassan, S. Gul, F. Flett, E. Hollingsworth, A.A. Dunne, A.J. Emmons, J.P. Hutchinson, M.J. Hibbs, S. Dyos, J.D. Kitson, E. Hiley, M. Rüdiger, D.G. Tew, D.J. Powell and M.A. Morse..........65–73
- Published as BJ Immediate Publication 8 December 2008, doi:10.1042/BJ20081646
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- N.J. Hassan, S. Gul, F. Flett, E. Hollingsworth, A.A. Dunne, A.J. Emmons, J.P. Hutchinson, M.J. Hibbs, S. Dyos, J.D. Kitson, E. Hiley, M. Rüdiger, D.G. Tew, D.J. Powell and M.A. Morse..........65–73
- A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition
- N.E. Torbett, A. Luna-Moran, Z.A. Knight, A. Houk, M. Moasser, W. Weiss, K.M. Shokat and D. Stokoe..........97–110
- Published as BJ Immediate Publication 22 May 2008, doi:10.1042/BJ20080639
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- N.E. Torbett, A. Luna-Moran, Z.A. Knight, A. Houk, M. Moasser, W. Weiss, K.M. Shokat and D. Stokoe..........97–110
- Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling
- C. Chaussade, G.W. Rewcastle, J.D. Kendall, W.A. Denny, K. Cho, L.M. Grønning, M.L. Chong, S.H. Anagnostou, S.P. Jackson, N. Daniele and P.R. Shepherd..........449–458
- Published as BJ Immediate Publication 16 March 2007, doi:10.1042/BJ20070003
- Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
- C. Chaussade, G.W. Rewcastle, J.D. Kendall, W.A. Denny, K. Cho, L.M. Grønning, M.L. Chong, S.H. Anagnostou, S.P. Jackson, N. Daniele and P.R. Shepherd..........449–458
