Biochemical Journal 417 part 1

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Volume 417, part 1 - 1 January 2009

Published on the Internet 12 December 2008

Reviews | Online Commentaries | Research Papers |

Reviews

How mitochondria produce reactive oxygen species
M.P. Murphy..........1–13
Published on the Internet 12 December 2008, doi:10.1042/BJ20081386
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The SR protein family of splicing factors: master regulators of gene expression
J.C. Long and J.F. Caceres..........15–27
Published on the Internet 12 December 2008, doi:10.1042/BJ20081501
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Darwin, Dover, ‘Intelligent Design’ and textbooks
K. Padian and N. Matzke..........29–42
Published on the Internet 12 December 2008, doi:10.1042/BJ20081534
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Online Commentaries

Inhibitors of apoptosis catch ubiquitin
K. Rajalingam and I. Dikic..........e1–e3
Published on the Internet 12 December 2008, doi:10.1042/BJ20082215 (see accompanying paper, pp. 149–160)
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New anti-cancer role for PDK1 inhibitors: preventing resistance to tamoxifen
C. Peifer and D.R. Alessi..........e5–e7
Published on the Internet 12 December 2008, doi:10.1042/BJ20082243 (see accompanying paper, pp. 361–370)
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Research papers

Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway
R.D. Finn, C.J. Henderson, C.L. Scott and C.R. Wolf..........43–54
Published as BJ Immediate Publication 9 September 2008, doi:10.1042/BJ20080740
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Characterization of the activity and folding of the glutathione transferase from Escherichia coli and the roles of residues Cys¹⁰ and His¹⁰⁶
X.-Y. Wang, Z.-R. Zhang and S. Perrett..........55–64
Published as BJ Immediate Publication 9 September 2008, doi:10.1042/BJ20071702
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Novel haem co-ordination variants of flavocytochrome P450 BM3
H.M. Girvan, H.S. Toogood, R.E. Littleford, H.E. Seward, W.E. Smith, I.S. Ekanem, D. Leys, M.R. Cheesman and A.W. Munro..........65–76
Published as BJ Immediate Publication 22 August 2008, doi:10.1042/BJ20081133
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The crystal structure of rabbit IgG-Fc
E. Girardi, M.D. Holdom, A.M. Davies, B.J. Sutton and A.J. Beavil..........77–83
Published as BJ Immediate Publication 3 September 2008, doi:10.1042/BJ20081355
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Human D-Tyr-tRNA^Tyr deacylase contributes to the resistance of the cell to D-amino acids
G. Zheng, W. Liu, Y. Gong, H. Yang, B. Yin, J. Zhu, Y. Xie, X. Peng, B. Qiang and J. Yuan..........85–94
Published as BJ Immediate Publication 14 August 2008, doi:10.1042/BJ20080617
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Structural requirements of KTS-disintegrins for inhibition of α₁β₁integrin
M.C. Brown, J.A. Eble, J.J. Calvete and C. Marcinkiewicz..........95–101
Published as BJ Immediate Publication 5 September 2008, doi:10.1042/BJ20081403
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Characterization of coenzyme binding and selectivity determinants in Mycobacterium tuberculosis flavoprotein reductase A: analysis of Arg¹⁹⁹ and Arg²⁰⁰ mutants at the NADP(H) 2′-phosphate binding site
M. Sabri, A.J. Dunford, K.J. McLean, R. Neeli, N.S. Scrutton, D. Leys and A.W. Munro..........103–112
Published as BJ Immediate Publication 3 September 2008, doi:10.1042/BJ20080466
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Differential regulation of threonine and tyrosine phosphorylations on protein kinase Cδ by G-protein-mediated pathways in platelets
S. Murugappan, R. Chari, V.M. Palli, J. Jin and S.P. Kunapuli..........113–120
Published as BJ Immediate Publication 24 July 2008, doi:10.1042/BJ20080235
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The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors
C. Desjobert, P. Noy, T. Swingler, H. Williams, K. Gaston and P.-S. Jayaraman..........121–132
Published as BJ Immediate Publication 19 August 2008, doi:10.1042/BJ20080872
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Clioquinol targets zinc to lysosomes in human cancer cells
H. Yu, Y. Zhou, S.E. Lind and W.-Q. Ding..........133–139
Published as BJ Immediate Publication 3 September 2008, doi:10.1042/BJ20081421
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Marked difference in membrane-protein-binding properties of the two isoforms of protein 4.1R expressed at early and late stages of erythroid differentiation
W. Nunomura, M. Parra, M. Hebiguchi, K.-I. Sawada, N. Mohandas and Y. Takakuwa..........141–148
Published as BJ Immediate Publication 11 August 2008, doi:10.1042/BJ20081372
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Ubiquitin binding modulates IAP antagonist- stimulated proteasomal degradation of c-IAP1 and c-IAP2
J.W. Blankenship, E. Varfolomeev, T. Goncharov, A.V. Fedorova, D.S. Kirkpatrick, A. Izrael-Tomasevic, L. Phu, D. Arnott, M. Aghajan, K. Zobel, J.F. Bazan, W.J. Fairbrother, K. Deshayes and D. Vucic..........149–160
Published as BJ Immediate Publication 22 October 2008, doi:10.1042/BJ20081885
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Cell surface delivery and structural re-organization by pharmacological chaperones of an oligomerization-defective α_1b-adrenoceptor mutant demonstrates membrane targeting of GPCR oligomers
M. Canals, J.F. Lopez-Gimenez and G. Milligan..........161–172
Published as BJ Immediate Publication 3 September 2008, doi:10.1042/BJ20081227
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Phosphoregulation of human Mps1 kinase
R.K. Tyler, M.L.H. Chu, H. Johnson, E.A. McKenzie, S.J. Gaskell and P.A. Eyers..........173–181
Published as BJ Immediate Publication 5 August 2008, doi:10.1042/BJ20081310
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High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo
S.K. Mantena, D.P. Vaughn, Jr, K.K. Andringa, H.B. Eccleston, A.L. King, G.A. Abrams, J.E. Doeller, D.W. Kraus, V.M. Darley-Usmar and S.M. Bailey..........183–193
Published as BJ Immediate Publication 28 August 2008, doi:10.1042/BJ20080868
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Atp6v1c1 is an essential component of the osteoclast proton pump and in F-actin ring formation in osteoclasts
S. Feng, L. Deng, W. Chen, J. Shao, G. Xu and Y.-P. Li..........195–203
Published on the Internet 12 December 2008, doi:10.1042/BJ20081073
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An N-terminally truncated Smad2 protein can partially compensate for loss of full-length Smad2
D. Das, R.A. Randall and C.S. Hill..........205–212
Published as BJ Immediate Publication 3 September 2008, doi:10.1042/BJ20080014
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Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions
D. Barak, A. Ordentlich, D. Stein, Q.-s. Yu, N.H. Greig and A. Shafferman..........213–222
Published as BJ Immediate Publication 26 August 2008, doi:10.1042/BJ20081276
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Macrophage activation induces formation of the anti-inflammatory lipid cholesteryl-nitrolinoleate
A.M. Ferreira, M.I. Ferrari, A. Trostchansky, C. Batthyany, J.M. Souza, M.N. Alvarez, G.V. López, P.R.S. Baker, F.J. Schopfer, V. O'Donnell, B.A. Freeman and H. Rubbo..........223–234
Published as BJ Immediate Publication 1 August 2008, doi:10.1042/BJ20080701
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Cytoplasmic polyadenylation-element-binding protein (CPEB)1 and 2 bind to the HIF-1α mRNA 3′-UTR and modulate HIF-1α protein expression
S. Hägele, U. Kühn, M. Böning and D.M. Katschinski..........235–246
Published as BJ Immediate Publication 27 August 2008, doi:10.1042/BJ20081353
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Palladacycles catalyse the oxidation of critical thiols of the mitochondrial membrane proteins and lead to mitochondrial permeabilization and cytochrome c release associated with apoptosis
D.P. Santana, P.A. Faria, E.J. Paredes-Gamero, A.C.F. Caires, I.L. Nantes and T. Rodrigues..........247–256
Published as BJ Immediate Publication 28 August 2008, doi:10.1042/BJ20080972
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Identification of new protein substrates for the chloroplast ATP-dependent Clp protease supports its constitutive role in Arabidopsis
T.M. Stanne, L.L.E. Sjögren, S. Koussevitzky and A.K. Clarke..........257–268
Published as BJ Immediate Publication 29 August 2008, doi:10.1042/BJ20081146
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Enzymes or redox couples? The kinetics of thioredoxin and glutaredoxin reactions in a systems biology context
C.S. Pillay, J.-H.S. Hofmeyr, B.G. Olivier, J.L. Snoep and J.M. Rohwer..........269–275
Published as BJ Immediate Publication 12 August 2008, doi:10.1042/BJ20080690
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Increased tyrosine phosphorylation of PSD-95 by Src family kinases after brain ischaemia
C.-P. Du, J. Gao, J.-M. Tai, Y. Liu, J. Qi, W. Wang and X.-Y. Hou..........277–285
Published as BJ Immediate Publication 22 August 2008, doi:10.1042/BJ20080004
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β-Arrestin1 interacts with the G-protein subunits β1γ2 and promotes β1γ2-dependent Akt signalling for NF-κB activation
M. Yang, R.L. He, J.L. Benovic and R.D. Ye..........287–296
Published as BJ Immediate Publication 27 August 2008, doi:10.1042/BJ20081561
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A single channel for nitrate uptake, nitrite export and nitrite uptake by Escherichia coli NarU and a role for NirC in nitrite export and uptake
W. Jia, N. Tovell, S. Clegg, M. Trimmer and J. Cole..........297–304
Published as BJ Immediate Publication 11 August 2008, doi:10.1042/BJ20080746
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The cytotoxic effect of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells is modulated by the expression level of MRP1 but not MDR1
L. Corich, A. Aranda, L. Carrassa, C. Bellarosa, J.D. Ostrow and C. Tiribelli..........305–312
Published as BJ Immediate Publication 19 August 2008, doi:10.1042/BJ20080918
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KLF5 enhances SREBP-1 action in androgen-dependent induction of fatty acid synthase in prostate cancer cell lines
M.-Y. Lee, J.-S. Moon, S.W. Park, Y.-k. Koh, Y.-H. Ahn and K.-S. Kim..........313–322
Published as BJ Immediate Publication 5 September 2008, doi:10.1042/BJ20080762
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Arabidopsis thaliana GLX2-1 contains a dinuclear metal binding site, but is not a glyoxalase 2
P. Limphong, M.W. Crowder, B. Bennett and C.A. Makaroff..........323–330
Published as BJ Immediate Publication 9 September 2008, doi:10.1042/BJ20081151
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When expressed in yeast, mammalian mitogen-activated protein kinases lose proper regulation and become spontaneously phosphorylated
V. Levin-Salomon, I. Maayan, L. Avrahami-Moyal, I. Marbach, O. Livnah and D. Engelberg..........331–340
Published as BJ Immediate Publication 8 September 2008, doi:10.1042/BJ20081335
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Cu,Zn-superoxide dismutase-driven free radical modifications: copper- and carbonate radical anion-initiated protein radical chemistry
D.C. Ramirez, S.E. Gomez-Mejiba, J.T. Corbett, L.J. Deterding, K.B. Tomer and R.P. Mason..........341–353
Published as BJ Immediate Publication 2 September 2008, doi:10.1042/BJ20070722
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The catalytic role of INCENP in Aurora B activation and the kinetic mechanism of Aurora B/INCENP
J. Yang, F. Zappacosta, R.S. Annan, K. Nurse, P.J. Tummino, R.A. Copeland and Z. Lai..........355–360
Published as BJ Immediate Publication 4 September 2008, doi:10.1042/BJ20081365
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Parallel RNAi and compound screens identify the PDK1 pathway as a target for tamoxifen sensitization
E. Iorns, C.J. Lord and A. Ashworth..........361–370
Published as BJ Immediate Publication 3 November 2008, doi:10.1042/BJ20081682
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A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family
A. Eberth, R. Lundmark, L. Gremer, R. Dvorsky, K.T. Koessmeier, H.T. McMahon and M.R. Ahmadian..........371–377
Published as BJ Immediate Publication 27 October 2008, doi:10.1042/BJ20081535
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Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3
M. Thangaraju, K.N. Carswell, P.D. Prasad and V. Ganapathy..........379–389
Published as BJ Immediate Publication 12 September 2008, doi:10.1042/BJ20081132
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Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains
M.B. Protty, N.A. Watkins, D. Colombo, S.G. Thomas, V.L. Heath, J.M.J. Herbert, R. Bicknell, Y.A. Senis, L.K. Ashman, F. Berditchevski, W.H. Ouwehand, S.P. Watson and M.G. Tomlinson..........391–400
Published as BJ Immediate Publication 16 September 2008, doi:10.1042/BJ20081126
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